A5086656145- Coronary Interventions and Diagnostics
- Angiogenesis and VEGF in Cancer
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Peripheral Artery Disease Management
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Nitric Oxide and Endothelin Effects
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Hormonal Regulation and Hypertension
- Heart Rate Variability and Autonomic Control
- Lymphatic System and Diseases
- Circular RNAs in diseases
- Cardiac Structural Anomalies and Repair
- Ultrasound and Hyperthermia Applications
- FOXO transcription factor regulation
- Receptor Mechanisms and Signaling
- Cardiovascular Disease and Adiposity
- Mechanical Circulatory Support Devices
- Advanced MRI Techniques and Applications
University of Miyazaki Hospital
2016-2023
Gifu University
2021-2023
Foundation of Cardiac Surgery Development
2022
Japan Medical Association
2016-2022
Yazaki (United States)
2016-2021
Louisiana State University Health Sciences Center New Orleans
2017-2018
Kurume University
2010-2017
Mayo Clinic
2016
Mayo Clinic in Arizona
2016
Previously published evidence on ischemic mitral regurgitation (IMR) and its adverse prognosis after myocardial infarction has been based the severity of IMR in subacute or chronic period infarction. However, state can vary from early stage to as a result various responses myocardium primary percutaneous coronary intervention (PCI).Standard echocardiography was serially performed 546 consecutive patients with first-onset acute (1) immediately their arrival (pre-PCI), (2) before discharge...
There is a paucity of data about the mechanisms by which sacubitril/valsartan (also known as LCZ696) improves outcomes in patients with heart failure. Specifically, effects on vascular function and NO bioavailability have not been investigated. We hypothesized that therapy increases circulating levels setting failure.Male spontaneously hypertensive rats underwent myocardial ischemia/reperfusion surgery to induce failure were followed for up 12 weeks serial echocardiography. Rats received (68...
Frailty is characterized by reduced biological reserves and weakened resistance to stressors, common in older adults. This study evaluated the prognostic implications of frailty at hospitalization elderly patients with acute myocardial infarction (AMI) who undergo percutaneous coronary intervention (PCI).We prospectively analysed 546 AMI aged ≥80 years undergoing PCI from 2009 2017. was classified based on impairment walking (unassisted, assisted, wheelchair/non-ambulatory), cognition...
To evaluate the clinical implications of additional pedal artery angioplasty (PAA) for patients with critical limb ischemia (CLI).Twenty-nine (mean age 77.8±8.6 years; 21 men) CLI (32 limbs) presenting de novo infrapopliteal and (Kawarada type 2/3) disease were reviewed. The need PAA was based on existence sufficient wound blush (WB) around target wounds after conventional above-the-ankle revascularization. Fourteen insufficient WB in 14 limbs received PAA, while 15 18 did not. groups...
AimsUnsatisfactory effects of therapeutic angiogenesis in critical limb ischaemia may be ascribed to use circulating angiogenic cells (CACs) derived from atherosclerotic patients with impaired neovascularization-related capacities. We tested whether ultrasound cell stimulation can restore the
The effects of therapeutic angiogenesis by intramuscular injection early pro-angiogenic cells (EPCs) to ischemic limbs are unsatisfactory. Oxidative stress in the may accelerate apoptosis injected EPCs, leading less neovascularization. Forkhead transcription factor 4 (FOXO4) was reported play a pivotal role signaling EPCs response oxidative stress. Accordingly, we assessed whether FOXO4-knockdown (FOXO4KD-EPCs) could suppress stress-induced and augment neovascularization capacity limbs. We...
Abstract Hyperuricemia is related to an increased risk of cardiovascular events from a meta-analysis and antihyperuricemia agents may influence cardiac function. We evaluated the effect febuxostat on echocardiographic parameters diastolic function in patients with asymptomatic hyperuricemia as prespecified endpoint subanalysis PRIZE study. Patients study were assigned randomly either add-on treatment group or control only appropriate lifestyle modification. Of 514 overall study, 65 (31 34...
A 77-year-old man with hypertension presented to the emergency department fever and cardiogenic shock 8 days after receiving first dose of BNT16B2b2 mRNA COVID-19 vaccine (Pfizer-BioNTech). Nucleic acid amplification via polymerase chain reaction a nasopharyngeal swab sample was negative for SARS-CoV-2. Electrocardiography showed atrial fibrillation poor R progression ST depressions in precordial leads (Panel A). Chest radiography cardiomegaly pulmonary congestion B). Echocardiography...
Background:Although paclitaxel-coated balloon (PCB) angioplasty is an effective procedure for in-stent restenosis (ISR) after coronary stenting, recurrent ISR PCB still occurs. The aim of this study was to evaluate the predictors ISR.
Background: As life expectancy rises, percutaneous coronary intervention (PCI) is being performed more frequently, even in elderly patients with acute myocardial infarction (AMI). This study evaluated outcomes of AMI complicated by heart failure (AMIHF), as defined Killip Class ≥2 at admission, who undergo PCI.
Background: Little is known regarding the postprocedural management of coronary artery perforation (CAP).
Abstract Hyperuricemia is reportedly associated with the progression of carotid intima-media thickness (IMT), a surrogate cardiovascular risks and events. However, factors IMT in patients asymptomatic hyperuricemia are largely unknown. In this post-hoc analysis multicenter, randomized PRIZE study, we analyzed data from total 326 who underwent ultrasonography blind manner at baseline 24 months to evaluate IMT. Mean maximum common artery (CCA) were measured central core laboratory. Factors...