- Anesthesia and Sedative Agents
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Oral and Maxillofacial Pathology
- Atrial Fibrillation Management and Outcomes
- Bone Tumor Diagnosis and Treatments
- Atomic and Subatomic Physics Research
- Dental Implant Techniques and Outcomes
- Neurological Disorders and Treatments
- Acute Ischemic Stroke Management
- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
- Complex Systems and Time Series Analysis
- Cardiac Arrhythmias and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Cerebrovascular and Carotid Artery Diseases
- Chaos control and synchronization
- Traffic and Road Safety
- Optical Imaging and Spectroscopy Techniques
- Herpesvirus Infections and Treatments
- Sexual function and dysfunction studies
- Automotive and Human Injury Biomechanics
- Time Series Analysis and Forecasting
- Sarcoma Diagnosis and Treatment
University Hospital of Basel
2016-2025
Technical University of Munich
2008-2024
Emory University
2020
Klinikum rechts der Isar
2008-2020
Danube Private University
2017-2020
University of Michigan
2016
Zero to Three
2013
University of California, San Diego
1990
Ludwig-Maximilians-Universität München
1990
Universitätskinderklinik
1988
In imaging functional connectivity (FC) analyses of the resting brain, alterations FC during unconsciousness have been reported. These results are in accordance with recent electroencephalographic studies observing impaired top-down processing anesthesia. this study, simultaneous records magnetic resonance (fMRI) and electroencephalogram were performed to investigate causality neural mechanisms propofol-induced loss consciousness by correlating fMRI directional (DC)...
The neural correlates of anesthetic-induced unconsciousness have yet to be fully elucidated. Sedative and anesthetic states induced by propofol been studied extensively, consistently revealing a decrease frontoparietal thalamocortical connectivity. There is, however, less understanding the effects halogenated ethers on functional brain networks.The authors recorded simultaneous resting-state magnetic resonance imaging electroencephalography in 16 artificially ventilated volunteers during...
Recent modeling and empirical studies support the hypothesis that large-scale brain networks function near a critical state. Similar functional connectivity patterns derived from resting state data network models at criticality provide further support. However, despite strong implication of relationship, there has been no principled explanation how shapes characteristic in networks. Here, we hypothesized science concept partial phase locking is underlying mechanism optimal We provides...
Abstract Background Preexisting factors such as age and cognitive performance can influence the electroencephalogram (EEG) during general anesthesia. Specifically, spectral EEG power is lower in elderly, compared to younger, subjects. Here, authors investigate age-related changes architecture patients undergoing anesthesia through a detailed examination of entropic measures. Methods The retrospectively studied 180 frontal recordings from anesthesia, induced with propofol/fentanyl maintained...
Permutation entropy (PeEn) is a complexity measure that originated from dynamical systems theory. Specifically engineered to be robustly applicable real-world data, the quantity has since been utilised for multitude of time series analysis tasks. In electroencephalogram (EEG) analysis, value changes PeEn correlate with clinical observations, among them onset epileptic seizures or loss consciousness induced by anaesthetic agents. Regarding this field application, present work suggests...
A large majority of tumors the reproductive system express gonadotropin releasing hormone receptor (GnRHR). Blockade and activation this with various antagonistic agonistic analogues native GnRH-I (pGlu1-His2-Trp3-Ser4-Tyr5-Gly6-Leu7-Arg8-Pro9-Gly10-NH2), respectively, has shown efficient suppression tumor growth. In study, GnRH-receptor been evaluated respect to its suitability as a target for in vivo peptide targeting using radiolabeled GnRH-analogues, parallel, new 18F- 68Ga-labeled GnRH...
Abstract Introduction Changes in neural activity induce changes functional magnetic resonance ( fMRI ) blood oxygenation level dependent BOLD signal. Commonly, increases signal are ascribed to cellular excitation. Objective The relationship between electrical and the human brain was probed on basis of burst suppression EEG . This condition includes two distinct states high low activity. Methods Resting‐state simultaneous measurements were acquired during deep sevoflurane anesthesia with...
Bone and soft tissue calcifications can often be visualized on panoramic radiographs, thus leading to presumptive diagnoses requiring further examinations. This cross-sectional study determined the prevalence of suspected carotid artery calcifications, tonsilloliths, calcified submandibular lymph nodes, sialoliths glands, idiopathic osteosclerosis in a Lower Austrian subpopulation.
Ordinal patterns are the common basis of various techniques used in study dynamical systems and nonlinear time series analysis. The present article focusses on computational problem turning into sequences ordinal patterns. In a first step, numerical encoding scheme for is proposed. Utilising classical Lehmer code, it enumerates by consecutive non-negative integers, starting from zero. This compact representation considerably simplifies working with digital domain. Subsequently, three...
Fatal and nonfatal drowning are among the leading causes of death lifelong severe neurological impairment children adolescents. This study aimed to complement research from Leipzig 1994–2008 seek trends within risk factors, treatments, outcomes throughout last decade. We retrospectively investigated data 47 inpatients aged 0–18 admitted University Department Pediatrics who matched ICD-10 code T75.1 2008 2020 compared them a preceding at same institution. also examined prognostic value...
Cemento-ossifying fibromas are rare, benign lesions of the head and neck regions. The origin these can be traced to periodontal ligament, because its cells able form cement, lamellar bone, or fibrous tissue. A rare case report a young Caucasian female with COF is described including follow-ups. She remained untreated for several years despite early radiographic findings lesion without definitive diagnosis. patient ultimately underwent radical surgery whole was removed. subsequent...
Lower birthweight is associated with an increased risk of cardiovascular diseases and diabetes. We hypothesized that inflammation body fat may be potential mediators for these inverse relationships.Healthy adults aged 25-41 years were enrolled in a prospective population-based cohort study the Principality Liechtenstein. Main exclusion criteria diabetes, overt disease or mass index > 35 kg/m(2) . Birthweight was self-reported by participants. White blood cell (WBC) count high-sensitivity...
Dental implants present an advanced technique for the rehabilitation of partial or edentulous patients. Tooth loss caused by caries, periodontal disease systemic factors often results in a decline bucco-lingual alveolar ridge dimension. Within one year initial bone width can be resorbed up to 50%. As consequence dental may limited and cannot performed conventional manner because risk dehiscence fenestrations. Bone blocks, guided regeneration (GBR), horizontal osteogenic distraction grafts...
Abstract Electroencephalogram (EEG)-based monitoring during general anesthesia may help prevent harmful effects of high or low doses anesthetics. There is currently no convincing evidence in this regard for the proprietary algorithms commercially available monitors. The purpose study was to investigate whether a more mechanism-based parameter EEG analysis (symbolic transfer entropy, STE) can separate responsive from unresponsive patients better than strictly probabilistic (permutation PE)...
We give a semantics to iterated update by preference relation on possible developments. An is sequence of formulas, giving (incomplete) information about successive states the world. A development models, describing trajectory through time. assume principle inertia and prefer those developments which are compatible with avoid unnecessary changes. The logical properties updates defined in this way considered, representation result proved.
Central odontogenic fibroma (COF) is a rare, benign, slow-growing intraosseous tumor, and accounts for 0.1% of all tumors. It often confused with other entities, such as keratocysts, ameloblastomas, myxomas. Complete enucleation followed by curettage the treatment choice COF to ensure lowest possible chance recurrence.We report case young Caucasian woman that went undiagnosed several years despite repeated radiologic examinations. Finally, massive tumor was surgically removed wound curetted....