- Osteomyelitis and Bone Disorders Research
- Infectious Diseases and Tuberculosis
- Orthopedic Infections and Treatments
- Sarcoma Diagnosis and Treatment
- Inflammatory Myopathies and Dermatomyositis
- Radiomics and Machine Learning in Medical Imaging
- Bone Tumor Diagnosis and Treatments
- Glioma Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Radiology practices and education
- Advanced MRI Techniques and Applications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Renal cell carcinoma treatment
- Medical Imaging Techniques and Applications
- Lymphoma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Genetic Neurodegenerative Diseases
- Meningioma and schwannoma management
- Gastric Cancer Management and Outcomes
- IgG4-Related and Inflammatory Diseases
- Blood Coagulation and Thrombosis Mechanisms
- Advanced X-ray and CT Imaging
- Neurosurgical Procedures and Complications
- Epilepsy research and treatment
- Fetal and Pediatric Neurological Disorders
University of Iowa Hospitals and Clinics
2013-2025
University of Iowa Stead Family Children’s Hospital
2020-2024
Tokyo Metropolitan Children's Medical Center
2024
Boston Children's Hospital
2024
University of Iowa
2008-2023
The Cancer Institute Hospital
2021
Okayama University
1998-2016
Yokohama City University
2009-2014
Aichi Cancer Center
2014
Yokohama City University Medical Center
2009
We performed interictal FDG-PET- and MRI-based hippocampal volumetric measurements on 18 adult patients with complex partial epilepsy of temporal lobe origin in whom we had identified their ictal focus by video-telemetry EEG. Sixteen (89%) regional hypometabolism, 11 (61%) focal 1.5-tesla T2-weighted MRI (two structural abnormalities, nine formation [HF] increased T2 signal), (50%) absolute HF atrophy ipsilateral to the focus. Ten (55%) abnormal L/R ratios, EEG All studies PET abnormalities....
We used positron emission tomography (PET) with 18F-2-deoxyglucose (FDG) and 15O water in 20 patients complex partial seizures to compare glucose metabolism blood flow temporal lobe epileptic foci identified by ictal scalp-sphenoidal video-EEG telemetry. Glucose was measured minutes after without moving the patient from scanner. also studied 11 99mTc-HMPAO single-photon computed (SPECT). Both local cerebral metabolic rate of (LCMRGlc) regional (rCBF) were significantly decreased cortex...
Objective. Serial magnetic resonance imaging (MRI) examinations are often needed in chronic nonbacterial osteomyelitis (CNO) to determine the objective response treatment. Our objectives this study were (1) develop a consensus-based MRI scoring tool for clinical and research use CNO; (2) evaluate interrater reliability agreement using whole-body (WB)-MRI from children with CNO. Methods. Eleven pediatric radiologists discussed definitions grading of signal intensity, size abnormality within...
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Perinatal venous infarcts are underrecognized clinically and at imaging. Neonates may be susceptible to because of hypercoagulable state, compressibility the dural sinuses superficial veins due patent sutures, immature cerebral drainage pathways, drastic physiologic changes brain circulation in perinatal period. About 43% cases pediatric sinovenous thrombosis occur neonatal Venous can recognized by ischemia or hemorrhage that does not respect an arterial territory. Knowledge pathways...
The neural crest is an important transient structure that develops during embryogenesis in vertebrates. Neural cells are multipotent progenitor migrate and develop into a diverse range of tissues throughout the body. Although originate from ectoderm, they can differentiate mesodermal-type or endodermal-type tissues. Some these include peripheral, autonomic, enteric nervous systems; chromaffin adrenal medulla; smooth muscles intracranial blood vessels; melanocytes skin; cartilage bones face;...
The association of diverticula with bowel habits is unclear. We therefore analyzed the between and in over 1000 Japanese individuals.Japanese subjects who underwent total colonoscopies at seven centers Japan from June to September 2013 were analyzed. Bowel evaluated using Gastrointestinal Symptom Rating Scale, stool form was assessed a part Bristol Scale Rome ΙΙΙ criteria. Diverticula diagnosed by colonoscopy transparent soft-short hood.The study 1066 subjects, 648 males 418 females (ratio,...
Abstract Neurofibromatosis type 1 (NF1) is a rare, autosomal dominant disease with variable clinical presentations. Large animal models are useful to help dissect molecular mechanisms, determine relevant biomarkers, and develop effective therapeutics. Here, we studied NF1 minipig model ( +/ex42del ) for the first 12 months of life evaluate phenotype development, track progression, provide comparison human subjects. Through systematic evaluation, have shown that compared littermate controls,...
Abdominal pain is a frequent problem encountered in the emergency department, and acute appendicitis well-recognized diagnosis. Laparoscopic appendectomy has become one of most common surgical procedures United States. Patients with history may experience recurrent right lower quadrant abdominal from an infrequently complication that occur when residual appendix becomes obstructed inflamed. We describe two cases stump pediatric patients review clinical imaging findings management.
RASopathies are a heterogeneous group of genetic syndromes caused by germline mutations in genes that encode components or regulators the Ras/mitogen-activated protein kinase (MAPK) signaling pathway. include neurofibromatosis type 1, Legius syndrome, Noonan Costello cardiofaciocutaneous central conducting lymphatic anomaly, and capillary malformation-arteriovenous malformation syndrome. These disorders grouped together as based on our current understanding Ras/MAPK Abnormal activation...
<b>SUMMARY:</b> We report a rare and unique complication of ventriculoperitoneal (VP) shunt malfunction. A progressively expansile, CSF-containing occipital intradiploic cyst developed in 15-year-old boy at the site cystoperitoneal draining Dandy-Walker cyst; was placed when 4 years old. proposed pathogenesis lesion is discussed.
<h3>BACKGROUND AND PURPOSE:</h3> Diffusion-weighted imaging may aid in distinguishing aggressive chordoma from nonaggressive chordoma. This study explores the prognostic role of apparent diffusion coefficient chordomas. <h3>MATERIALS METHODS:</h3> Sixteen patients with residual or recurrent were divided postoperatively into those an tumor, defined as a growing tumor having doubling time <1 year, and on follow-up MR images. The ability ADC to predict phenotype was investigated by receiver...