A5044748271- Radioactive contamination and transfer
- Nuclear and radioactivity studies
- Advanced Surface Polishing Techniques
- Radioactivity and Radon Measurements
- Graphite, nuclear technology, radiation studies
- Epigenetics and DNA Methylation
- Risk and Safety Analysis
- Advanced Data Storage Technologies
- Traditional Chinese Medicine Studies
- Advanced machining processes and optimization
- Marine and Coastal Research
- 3D IC and TSV technologies
- Radiation Detection and Scintillator Technologies
- Healthcare and Venom Research
- DNA and Nucleic Acid Chemistry
- Caching and Content Delivery
- Atmospheric and Environmental Gas Dynamics
- Diffusion and Search Dynamics
- RNA modifications and cancer
- Nutrition, Health and Food Behavior
- Parallel Computing and Optimization Techniques
- Monoclonal and Polyclonal Antibodies Research
- VLSI and Analog Circuit Testing
- Integrated Circuits and Semiconductor Failure Analysis
- Interconnection Networks and Systems
Boston University
2024
University of Massachusetts Boston
2024
Korea Atomic Energy Research Institute
2014-2023
Korea Energy Economics Institute
2015-2022
Korea Advanced Institute of Science and Technology
2020-2022
Gyeongsang National University
2020
Seoul Medical Center
2018
Catholic University of Korea
2018
Yonsei University
2005-2017
Korea Institute for Advanced Study
2012-2015
Among various nanoparticles, mesoporous silica nanoparticles (MSNs) have attracted extensive attention for developing efficient drug-delivery systems, mostly due to their high porosity and biocompatibility. However, the small pore size, generally below 5 nm in diameter, potential drugs that are loaded into been limited molecules. Herein, a interfering RNA (siRNA) delivery strategy based on MSNs possessing pores with an average diameter of 23 is presented. The siRNA regarded as powerful gene...
Virtually all patients with BRAF-mutant melanoma develop resistance to MAPK inhibitors largely through nonmutational events. Although the epigenetic landscape is shown be altered in therapy-resistant melanomas and other cancers, a specific targetable mechanism has not been validated. Here, we evaluated corepressor for element 1-silencing transcription factor (CoREST) repressor complex recently developed bivalent inhibitor corin within context of phenotype plasticity therapeutic resistance....
Co-immunoprecipitation (co-IP) has become a standard technique, but its protein-band output provides only static, qualitative information about protein-protein interactions. Here we demonstrate real-time single-molecule co-IP technique that generates videos of individual interactions as they occur in unpurified cell extracts. By analysing single Ras-Raf with 50-ms time resolution, have observed transient intermediates the interaction and determined all essential kinetic rates. Using this...
We recently developed a marine environment exposure dose assessment model to evaluate the radiological doses public following accidents. The six pathways were considered: external through beach activity, swimming, and boating internal inhalation via sea spray, ingestion of seawater during swimming seafood. A for estimating radionuclide concentration in organisms present was based on equilibrium model, taking into account realistic aspects related food intake data availability input...
The environmental and health effects of the transport diffusion pollutants released into atmosphere ocean due to a nuclear accident must be evaluated rapidly accurately ensure safety surrounding population ecosystem. Since Fukushima in 2011, web-based emergency support system named Radiological Accident Preparedness System Korea (RAPS-K) has been developed predict dispersion radioactive materials environment estimate dose assessment for humans. is composed atmospheric dispersion, marine...
Accurate, rapid, and cost-effective screening tests for hepatitis B virus (HBV) C (HCV) infection may be useful in laboratories that cannot afford automated chemiluminescent immunoassays (CLIAs). We evaluated the diagnostic performance of a novel rapid fluorescent lateral flow immunoassay (LFIA).A LFIA using small bench-top fluorescence reader, Automated Fluorescent Immunoassay System (AFIAS; Boditech Med Inc., Chuncheon, Korea), was developed qualitative detection surface antigen (HBsAg),...
This study was conducted to investigate the efficacy of black cohosh (Cimicifuga racemosa) and St. John's wort (Hypericum perforatum) in women with climacteric symptoms, assess their effects on vaginal atrophy, hormone levels, lipid profiles.In this double-blind randomized, placebo-controlled, multicenter study, 89 peri- or postmenopausal experiencing symptoms were treated extract (Gynoplus), Jin-Yang Pharm., Seoul, Korea) a matched placebo for 12 weeks. Climacteric complaints evaluated by...
This study was performed to develop questionnaire of cold-heat pattern identification(PI) based on usual symptoms for general people, and we analyzed reliability the questionnaire. We reviewed PI advanced research selected twenty-three items through three time experts meeting. Three hundred fifty nine healthy subjects were joined in this study. As a results, Cronbach’s α 0.79 0.83. According factor analysis about fifteen-chosen questionnaires, each consisted two factors Convergence 56.46%...
The aims of this study were to evaluate the reliability and validity cold heat pattern identification questionnaire (CHPIQ). From July 2015 December 2015, 120 participants, university faculties, filled out CHPIQ by way self-reporting. Then two Korean medical doctors independently diagnosed them whether they belonged (CP) or not, (HP) not. We evaluated internal consistency using Cronbach's alpha coefficient, sensitivity specificity through receiver operating characteristic-curve. (Cronbach's...
The facilitated diffusion effect on protein-DNA binding is studied. A rigorous theoretical approach presented to deal with the coupling between one-dimensional and three-dimensional diffusive motions. For a simplified model, present can provide numerically exact results, which are confirmed by lattice-based Monte Carlo simulations.
Demographic changes have a profound impact on residential energy consumption. The number of single-person households is rapidly increasing around the world and percentages elderly individuals in populations almost all countries are expanding. objective our research was to analyze how intensity, defined as annual consumption per capita unit finished area household’s house, those impacts interact with each other using South Korea case study. Our findings suggest that rise solo living an ageing...
Excited-state reversible geminate recombination with two different lifetimes and quenching is investigated in dimensions. From the exact Green function Laplace domain, analytic expressions of two-dimensional survival binding probabilities are obtained at short long times. We find that a new pattern kinetic transition occurs The long-time effective show (ln t)−1→constant→et depending on rate constants while t−1(ln t)−2→t−1→et.
This research aims to design a new phase-change RAM (PRAM)-based main memory structure, supporting the advantages of PRAM while providing performance similar that conventional DRAM memory. To replace DRAMs with non-volatile PRAMs as components, comparable access latency, overall cost, power dissipation, and cell endurance should be supported. For these goals, we propose system consisting converter an array single-level (SLC)/multi-level (MLC) PRAMs. The consists aggressive fetching...
A machine learning technique using image patterns has been proposed to predict the concentrations of particulate matter with an aerodynamic diameter <10 μm (PM10) originating from on-road vehicles. The analysis process included measurements PM10 concentrations, data collection on vehicle transportation and convolutional neural network (CNN). Preprocessing procedures involving high-pass filtering were used remove outliers measured PM10, multi-neuron components modeled by connecting estimated...
Abstract The reversible geminate transfer reaction, A*+B↔C*+D, has been studied in two dimensions. For the excited‐state reaction with different lifetimes and quenching, exact analytical Green functions have generalized for an arbitrary initial condition Laplace domain. Long‐time asymptotic behaviors of survival probabilities analyzed time domain as well short‐time expressions. two‐dimensional found to show logarithmic decay ${\left( {\ln t} \right)^{ - 1} }$ or ${t^{ \left( 2} at long...
In recent years, the halloysite (Al₂Si₂O5(OH)₄ · 2H₂O) has been highlighted owing to its naturally occurring one-dimensionalmicrostructure that enables versatile applications. Due demand for enhancing surface interaction, several types of research such as acid/base treatments have conducted on nanotubes. The objective this study is investigate structural and properties thermally treated halloysites under reducing atmosphere. heat treatment carried out in a gas-flow furnace at 400-800 °C...
A novel built-in redundancy analysis (BIRA) is proposed for embedded memories. The BIRA algorithm has two phases. In the first phase, detected faults are collected to area-efficient fault storing content addressable memory (CAM). order determine a correct repair solution, spare memories allocated in second phase using linear feedback shift register (LFSR) with fast analyzing speed. Experimental results show that achieves optimal rate and very low area overhead.
Accidentally released radionuclides are dispersed into the environment and cause human exposure through various pathways. Concerns about radiological impacts of a possible Nuclear power plant (NPP) accident in neighboring countries, especially China, increasing Korea. Dose assessments for hypothetical nuclear accidents Korea (Hanbit Wolsong NPPs) China (Tianwan NPP) were conducted using developed Korean code system. The results show that there is possibility Tianwan NPP could have slightly...
A large amount of radioactive material was released from the Fukushima Daiichi Nuclear Power Plant (FDNPP) in 2011 and dispersed into environment. Though seven years have passed since accident, some parts Japan are still under influence radionuclide contamination, especially Prefecture prefectures neighboring Prefecture. The long-term effective doses contributions each exposure pathway (5 pathways) (131I, 134Cs, 137Cs) were evaluated for people living regions using a developed dose...