Amelia Grosso
- Asthma and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory and Cough-Related Research
- Pulmonary Hypertension Research and Treatments
- Inhalation and Respiratory Drug Delivery
- COVID-19 Clinical Research Studies
- Cystic Fibrosis Research Advances
- Tracheal and airway disorders
- Vitamin D Research Studies
- COVID-19 diagnosis using AI
- Allergic Rhinitis and Sensitization
- Delphi Technique in Research
- Environmental Toxicology and Ecotoxicology
- Connective tissue disorders research
- Bone health and osteoporosis research
- Eosinophilic Esophagitis
- Pregnancy and Medication Impact
- Esophageal and GI Pathology
- SARS-CoV-2 and COVID-19 Research
- Air Quality and Health Impacts
- Respiratory viral infections research
- Physiological and biochemical adaptations
- Insect and Pesticide Research
- COVID-19 epidemiological studies
- Airway Management and Intubation Techniques
Istituti di Ricovero e Cura a Carattere Scientifico
2013-2024
Policlinico San Matteo Fondazione
2011-2024
University of Pavia
2013-2024
University Hospital Foundation
2015-2016
<i>Background:</i> The prevalence rates of smoking in subjects with asthma have frequently been reported as similar to those the general population; however, available data are not up-to-date. There is only limited and somewhat conflicting information on long-term effects health outcomes among population-based cohorts asthma. We aimed investigate changes habits their forced expiratory volume 1 s (FEV<sub>1</sub>) comparison rest population, focusing healthy smoker...
There is, so far, no universal definition of severe asthma. This usually relies on: number exacerbations, inhaled therapy, need for oral corticosteroids, and respiratory function. The use such parameters varies in the different definitions used. Thus, according to chosen, each patient may result having asthma or not. aim this study was evaluate how choice a specific can change allocation patients.Data collected from Severe Asthma Network Italy (SANI) registry were analyzed. All patients...
Background Only few longitudinal studies on the course of asthma among adults have been carried out. Objective The aim present prospective study, out between 2000 and 2009 in Italy, is to assess remission control with asthma, as well their determinants. Methods All subjects current (21–47 years) identified Italian Study Asthma Young Adults 6 centres were followed up. was assessed at follow-up 2008–2009 (n = 214), baseline follow-up. related potential determinants by a binomial logistic...
Over the years it has been widely stated that approximately one-third of asthmatic women experience worsening disease during pregnancy. However, literature not reviewed systematically and meta-analytic reviews include old studies. This study aimed to examine whether prevalence asthma pregnancy is still consistent with prior estimate or reduced.A detailed Clinical Questionnaire on respiratory symptoms, medical history, medication, use services, occupation, social status, home environment...
Summary Background Fat intake has been associated with respiratory diseases, conflicting results. Objective We studied the association between asthma and rhinitis dietary fats, their food sources in an Italian population. Methods Clinical nutritional information was collected for 871 subjects (aged 20‐84) from population‐based multi‐case‐control study Genes Environment Interaction Respiratory Diseases ( GEIRD ): 145 current CA ), 77 past PA 305 344 controls. Food using EPIC (European...
Asthma guidelines from the Global Initiative for (GINA) and National Heart, Lung, Blood Institute provide conflicting definitions of airflow obstruction, suggesting a fixed forced expiratory volume in 1 s (FEV(1))/forced vital capacity (FVC) cut-off point lower limit normality (LLN), respectively. The LLN was recommended by recent American Thoracic Society/European Respiratory Society on lung function testing. problem using points is that they are set regardless age sex an attempt to...
Background: Early identification of patients with COPD and prone to more rapid decline in lung function is particular interest from both a prognostic therapeutic point view. The aim this study was identify the clinical, functional imaging characteristics associated FEV1 COPD. Methods: Between 2001 2005, 131 outpatients moderate stable condition under maximum inhaled therapy underwent clinical interview, pulmonary tests HRCT chest were followed for at least 3 years. Results: Twenty-six...
Cardiovascular and respiratory diseases can frequently coexist. Understanding their link may improve disease management. We aimed at assessing the associations of chronic bronchitis (CB), asthma rhinitis with cardiovascular risk factors in general population.We used data collected Gene Environment Interactions Respiratory Diseases study, an Italian multicentre, multicase-control study. Among 2463 participants (age 21-86, female 50%) who underwent standardized interviews, skin prick lung...
Personal air formaldehyde (air-FA) was measured as risk factor of airways inflammation and oxidative stress (SO) induction. Overall, 154 police officers were enrolled from two differently urbanised Italian cities, Turin Pavia. Urinary F2t-isoprostane (15-F2t-IsoP), a prostaglandin-like compound, quantified biomarker general OS in vivo fractional exhaled nitric oxide (FeNO) for monitoring local inflammatory processes. cotinine tobacco smoking exposure. Traffic living showed an increased level...
After successful pulmonary endoarterectomy (PEA), patients may still suffer from exercise limitation, despite normal vascular resistance. We sought to assess the proportion of these after extension PEA frail patients, and determinants limitation. Out 553 treated with 2008 2016 at our institution, a cohort 261 was followed up 12 months. They underwent clinical, haemodynamic, echocardiographic, respiratory function tests treadmill testing. A reduced capacity defined as Bruce test distance <...
<b><i>Background:</i></b> It is not clear whether mepolizumab differently effective in allergic and nonallergic severe eosinophilic asthmatics (SEA) real life. <b><i>Objective:</i></b> We tested effectiveness allergic/nonallergic SEA A strict criterion to identify the 2 phenotypes was used. <b><i>Method:</i></b> retrospectively considered 134 consecutive patients divided into allergic, with a positivity at least 1...
Background: Double aortic arch is a rare congenital and complete vascular ring around trachea esophagus. It usually diagnosed during infancy. The symptoms are generally related to respiratory gastroesophageal tracts. Case presentation: A 20-year-old female patient was referred our outpatient clinic for persistent dry cough. She had history of an episode inhalation food bolus as infant recurrent bronchitis, anorexia allergic bronchial asthma since the childhood. Since beginning, intrathoracic...
COVID-19 modified the healthcare system. Nasal-pharyngeal swab (NPS), with real-time reverse transcriptase-polymerase (PCR), is gold standard for diagnosis; however, there are difficulties related to procedure that may postpone it. The study aims evaluate whether other elements than PCR-NPS reliable and confirm diagnosis of COVID-19. This a cross-sectional on data from Lung Unit Pavia (confirmed) at Emergency Palermo (suspected). was confirmed by positive NPS, suspected tested negative. We...