Alan Kastner
A5078465570- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Retinal Imaging and Analysis
- Magnesium in Health and Disease
- Long-Term Effects of COVID-19
- Cancer-related Molecular Pathways
- Infective Endocarditis Diagnosis and Management
- Retinal and Macular Surgery
- Toxin Mechanisms and Immunotoxins
- Blood Pressure and Hypertension Studies
- Ocular Oncology and Treatments
- Corneal Surgery and Treatments
- Plant tissue culture and regeneration
- Cardiovascular and exercise physiology
- Retinal and Optic Conditions
- Transgenic Plants and Applications
- Cardiac Valve Diseases and Treatments
- Muscle metabolism and nutrition
- COVID-19 and healthcare impacts
- Viral Infections and Immunology Research
- Intraocular Surgery and Lenses
- Sodium Intake and Health
- COVID-19 Clinical Research Studies
- Alcohol Consumption and Health Effects
University College London
2020-2023
Moorfields Eye Hospital NHS Foundation Trust
2020-2023
National Institute for Health Research
2023
Moorfields Eye Hospital
2023
National Health Service
2023
Pontificia Universidad Católica de Chile
2016-2022
Ophthalmology Associates (United States)
2021
Theresian Military Academy
2018-2019
Carol I National Defence University
2018-2019
Nottingham University Hospitals NHS Trust
2019
ABSTRACT OBJECTIVES To identify the sociodemographic, lifestyle, comorbidity and antihypertensive medication associations with development of hospitalisation covid-19 in an English population. DESIGN Prospective cohort study SETTING The population-based UK Biobank was linked to test results. PARTICIPANTS Individuals resident England alive 2020. MAIN OUTCOME MEASURES Cases (n=605) were defined by a positive result conducted between 16 th March April 2020, during restricted testing policy for...
Serum lipids are modifiable, routinely collected blood test features associated with cardiovascular health. We examined the association of commonly serum lipid measures (total cholesterol [TC], high-density lipoprotein [HDL-C], low-density [LDL-C], and triglycerides) intraocular pressure (IOP).Cross-sectional study in UK Biobank European Prospective Investigation into Cancer Nutrition (EPIC)-Norfolk cohorts.We included 94 323 participants from (mean age, 57 years) 6230 EPIC-Norfolk 68...
To examine the associations of alcohol consumption with glaucoma and related traits, to assess whether a genetic predisposition modified these associations, perform Mendelian randomization (MR) experiments probe causal effects. Cross-sectional observational gene–environment interaction analyses in UK Biobank. Two-sample MR using summary statistics from large consortia. Biobank participants data on intraocular pressure (IOP) (n = 109 097), OCT-derived macular inner retinal layer thickness...
Excessive dietary sodium intake has known adverse effects on intravascular fluid volume and systemic blood pressure, which may influence intraocular pressure (IOP) glaucoma risk. This study aimed to assess the association of urinary excretion, a biomarker intake, with related traits, determine whether this relationship is modified by genetic susceptibility disease. Cross-sectional observational gene-environment interaction analyses in population-based UK Biobank study. Up 103 634 individuals...
The aim of this study was to validate the Glaucoma Risk Stratification Tool (GLAUC-STRAT-fast) currently recommended by Royal College Ophthalmologists for risk stratification patients with glaucoma in UK National Health Service Hospital Eye Service.GLAUC-STRAT fast applied LiGHT trial participants risk-stratifying worse eye each patient at baseline and after 3 years treatment. Metrics disease severity or treatment intensity used validation were: increased number monitoring visits...
Objectives: Mitral valve repair in patients with acute endocarditis is still controversially discussed, although improvements techniques of MVRep have extended its feasibility complex lesions, but experience limited. In this report we aim to evaluate the durability repairs.
Objective: Disorders in sports or mental stress concerning electolytes, metabolism and blood pressure values are of recent interest under the aspect cardiovascular disease. In this context these parameters were investigated both running bungee sports. Design method: At Austrian Military Academy Wiener Neustadt, capillary 20 officer trainees (run) 34 (bungee jump) has been sampled 10 minutes before after respiratory contest, whereby BE, magnesium ionized, lactate, glucose, Ca/Mg ratio (Phox-M...
Objective: A pathogenetic role of decreased magnesium concentrations has been described in the development primary hypertension.Ionized is only electrolyte sensible enough to change - this case decrease already along with mentally induced CO2. Physically changes after a run proper, include correlative ionized calcium decreasing HCO3 and base excess at same time increasing ioniozed concentrations.This means, that moderate exertion not severe transfer appreciable amounts into blood remove much...