A5024500541- Nutritional Studies and Diet
- Diet and metabolism studies
- Obesity, Physical Activity, Diet
- Nutrition and Health in Aging
- Consumer Attitudes and Food Labeling
- Fatty Acid Research and Health
- Nutrition, Genetics, and Disease
- Bone health and osteoporosis research
- Alcohol Consumption and Health Effects
- Magnesium in Health and Disease
- Cancer Risks and Factors
- Sodium Intake and Health
- Antioxidant Activity and Oxidative Stress
- Vitamin D Research Studies
- Diet, Metabolism, and Disease
- Parathyroid Disorders and Treatments
- Folate and B Vitamins Research
- Dietary Effects on Health
- Glaucoma and retinal disorders
- Colorectal Cancer Screening and Detection
- Vitamin C and Antioxidants Research
- Liver Disease Diagnosis and Treatment
- Tea Polyphenols and Effects
- Retinal Diseases and Treatments
- Phytoestrogen effects and research
Örebro University
2019-2025
University of East Anglia
2010-2024
University of Cambridge
2013-2022
Vision Eye Institute
2022
Atrium Health Wake Forest Baptist
2022
Medical Research Council
2010-2019
Cambridge School
2013
MRC Epidemiology Unit
2010-2012
MRC Biostatistics Unit
2010
Addenbrooke's Hospital
2010
The association between quantity of fruit and vegetable (F&V) intake risk type 2 diabetes (T2D) is not clear, the relationship with variety unknown. current study examined both F&V T2D.
High dietary saturated fat intake is associated with higher blood concentrations of low-density lipoprotein cholesterol (LDL-C), an established risk factor for coronary heart disease. However, there increasing interest in whether various oils or fats different fatty acid profiles such as extra virgin coconut oil may have metabolic effects but trials reported inconsistent results. We aimed to compare changes lipid profile, weight, distribution and markers after four weeks consumption 50 g...
The Oxford WebQ is a web-based 24-h dietary assessment method which has been used in UK Biobank and other large prospective studies. food composition table to calculate nutrient intakes recently replaced with the Nutrient Databank, data closer time when participants completed questionnaire, new variables were incorporated. Here we describe updated version of questionnaire calculation, compare previous used.207,144 ≥ 1 WebQs, means standard deviations averaged for all assessments. Spearman...
Abstract Background The identification of effective dementia prevention strategies is a major public health priority, due to the enormous and growing societal cost this condition. Consumption Mediterranean diet (MedDiet) has been proposed reduce risk. However, current evidence inconclusive typically derived from small cohorts with limited cases. Additionally, few studies have explored interaction between genetic risk dementia. Methods We used Cox proportional hazard regression models explore...
The aim of this study was to investigate the association between total and types dairy product intake risk developing incident type 2 diabetes, using a food diary.A nested case-cohort within EPIC-Norfolk Study examined, including random subcohort (n = 4,000) cases diabetes 892, 143 in subcohort) followed-up for 11 years. Diet assessed prospective 7-day diary. Total (g/day) estimated categorised into high-fat (≥3.9%) low-fat (<3.9% fat) dairy, by subtype yoghurt, cheese milk. Combined...
Background Flavonoids are a group of phenolic secondary plant metabolites that ubiquitous in plant-based diets. Data from anthropological, observational and intervention studies have shown many flavonoids bioactive. For this reason, there is an increasing interest investigating the potential health effects these compounds. The translation findings into context general public requires detailed information on habitual dietary intake. However, only limited data currently available for European...
This study aimed to evaluate the association of types sugar-sweetened beverages (SSB) (soft drinks, sweetened-milk beverages, sweetened tea/coffee), artificially (ASB) and fruit juice with incident type 2 diabetes determine effects substituting non-SSB for SSB population-attributable fraction due total sweet beverages.Beverage consumption 25,639 UK-resident adults without at baseline (1993-1997) in European Prospective Investigation into Cancer Nutrition (EPIC)-Norfolk was assessed using...
Dietary interventions with flavan-3-ols have shown beneficial effects on vascular function. The translation of these findings into the context health general public requires detailed information habitual dietary intake. However, only limited data are currently available for European populations. Therefore, in present study, we assessed intake flavan-3-ol monomers, proanthocyanidins (PA) and theaflavins Union (EU) determined their main food sources using EFSA (European Food Safety Authority)...
In the past, vitamins and minerals were used to cure deficiency diseases. Supplements nowadays are with aim of reducing risk chronic diseases which origins complex. Dietary supplement use has increased in UK over recent decades, contributing nutrient intake population, but not necessarily proportion population that is sub-optimally nourished; therefore, below estimated average requirement potentially increasing number at an above safety limits. The may be objectively monitored using...
Abstract Purpose The UK Biobank study collected detailed dietary data using a web-based self-administered 24 h assessment tool, the Oxford WebQ. We aimed to describe comprehensive food grouping system for this questionnaire and report intakes key sources of selected nutrients by sex education. Methods Participants with at least one valid 24-h were included ( n = 208,200). Dietary grouped based on presence as well culinary use, processing, plant/animal origin. For each group, we calculated...
BackgroundThe American Heart Association has prioritised seven cardiovascular health metrics to reduce the burden, including: body mass index, healthy diet, physical activity, smoking status, blood pressure, glycated haemoglobin A1c and total cholesterol. The aim of current study was assess association between Association-defined risk events in EPIC-Norfolk prospective study.
We examined the association of habitual caffeine intake with intraocular pressure (IOP) and glaucoma whether genetic predisposition to higher IOP modified these associations. also assessed coffee consumption was related IOP.Cross-sectional study in UK Biobank.We included 121 374 participants (baseline ages, 39-73 years) data on tea (collected 2006-2010) corneal-compensated measurements 2009. In a subset 77 906 up 5 web-based 24-hour-recall food frequency questionnaires (2009-2012), we...
Serum lipids are modifiable, routinely collected blood test features associated with cardiovascular health. We examined the association of commonly serum lipid measures (total cholesterol [TC], high-density lipoprotein [HDL-C], low-density [LDL-C], and triglycerides) intraocular pressure (IOP).Cross-sectional study in UK Biobank European Prospective Investigation into Cancer Nutrition (EPIC)-Norfolk cohorts.We included 94 323 participants from (mean age, 57 years) 6230 EPIC-Norfolk 68...
Abstract Carotenoids are found in abundance fruit and vegetables, may be involved the positive association of these foods with bone health. This study aimed to explore associations dietary carotenoid intakes plasma concentrations density status osteoporotic fracture risk a European population. Cross-sectional analyses ( n 14 803) status, using calcaneal broadband ultrasound attenuation (BUA) longitudinal 25 439) cases were conducted on data from prospective Prospective Investigation into...
The objective of the present study was to investigate associations between sugar intake and overweight using dietary biomarkers in Norfolk cohort European Prospective Investigation into Cancer Nutrition (EPIC-Norfolk).
Loneliness has been associated with adverse health outcomes, including age-related diseases an inflammatory etiology such as cardiovascular disease. We aimed to identify potential biological pathways linking loneliness morbidity and mortality by examining associations of biomarkers. Participants in the English Longitudinal Study Ageing (n = 3239) aged 50 years or older average age 64 years, provided data waves 4 (2008/2009) 6 (2012/2013). Linear regression conditional change models had three...
Abstract Background Measures of abdominal adiposity are strongly associated with all-cause mortality and cardiovascular disease (CVD). However, data limited conflicting regarding the consequences changes in body fat distribution. The main aims this paper to investigate association between waist circumference (WC) CVD examine these relation concurrent weight. Methods European Prospective Investigation into Cancer Nutrition (EPIC-Norfolk) study recruited 25,639 participants 1993 1997, aged...