A5003771494- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Respiratory Support and Mechanisms
- Liver Disease Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
- Renal Diseases and Glomerulopathies
- Nanoparticle-Based Drug Delivery
- Cardiac Ischemia and Reperfusion
- Ultrasound in Clinical Applications
- Pediatric Hepatobiliary Diseases and Treatments
- Airway Management and Intubation Techniques
- Cardiovascular Function and Risk Factors
- Anesthesia and Neurotoxicity Research
- Characterization and Applications of Magnetic Nanoparticles
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Erythropoietin and Anemia Treatment
- Functional Brain Connectivity Studies
- COVID-19 Clinical Research Studies
- Mitochondrial Function and Pathology
- Vasculitis and related conditions
- Diet, Metabolism, and Disease
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Lipid metabolism and disorders
- Metal-Organic Frameworks: Synthesis and Applications
Wannan Medical College
2010-2024
First Affiliated Hospital of Wannan Medical College
2010-2024
Peking Union Medical College Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Southeast University
2024
Suzhou Research Institute
2024
China Three Gorges University
2021-2023
Nanjing Agricultural University
2022-2023
Zhejiang Pharmaceutical College
2023
Sun Yat-sen University
2021-2023
Anemia commonly aggravates the severity of respiratory diseases, whereas thus far, few studies have elucidated impact anemia on coronavirus disease 2019 (COVID-19). The aim this study was to evaluate clinical characteristics patients with anemia, and further explore relationship between COVID-19. In single-center, retrospective, observational study, a total 222 confirmed admitted Wuhan Ninth Hospital from 1 December 20 March 2020 were recruited, including 79 143 without anemia. Clinical...
The incidence of hypertriglyceridemia-associated acute pancreatitis (HTG-AP) is increasing. Plasmapheresis theoretically effective in removing triglyceride from plasma, but whether it confers clinical benefits unclear.To assess the association between plasmapheresis and duration organ failure among patients with HTG-AP.This an a priori analysis data multicenter, prospective cohort study enrolled 28 sites across China. Patients HTG-AP were admitted within 72 hours disease onset. first patient...
The coprecipitation method is widely recognized as a green, biocompatible, and low-cost synthetic pathway. However, the conventional approach used for generating iron oxide nanoparticles (IONPs) yields particles with inadequate crystallinity magnetism challenges in controlling their morphology. These limitations restrict potential uses of IONPs magnetic resonance imaging (MRI). This study introduces technique called hydrocooling magnetically internal heating (HMIHC) to address these enhance...
No specific triglyceride-lowering therapy is recommended in patients with hypertriglyceridemia-associated acute pancreatitis (HTG-AP), primarily because of the lack quality evidence. This study aimed to describe practice variations therapies for early HTG-AP and assess whether more rapid triglyceride decline associated improving organ failure. a multicentre, prospective cohort recruiting elevated plasma (> 11.3 mmol/L) admitted within 72 h from onset symptoms. Patients were dichotomised on...
Objective We aimed to describe the trends and influence factors in prevalence, awareness, treatment, control of hypertension among US Adults from 1999 2018. Methods utilized data National Health Nutrition Examination Survey (NHANES) spanning ten survey cycles (n = 53,496). Prevalence, were calculated using weights. Joinpoint regression survey-weighted generalized linear models used analyze factors, respectively. Results The estimated prevalence increased significantly 33.53% 40.58% (AAPC...
A drug carrier featuring ZIF-8 on the surface of carboxy-functionalized Fe 3 O 4 was synthesized and impregnated with CUR by SSI to achieve distinguished DLC.
Sepsis and sepsis-associated intestinal barrier dysfunction are common in intensive care units, with high mortality. The aim of this study is to investigate whether Polo-like kinase 1 (PLK1) ameliorates sepsis-induced the epithelium. mouse was disrupted after Lipopolysaccharide (LPS) injection due epithelial cell apoptosis proliferation inhibition, accompanied by decreased PLK1. In HT-29 cells, LPS stimulation induced inhibited proliferation. Overexpression PLK1 partly rescued inhibition...
Abstract Background Social anxiety disorder (SAD) is a prevalent mental diagnosed in childhood and adolescence. Theories regarding brain development SAD suggest close link between neurodevelopmental dysfunction at the adolescent juncture SAD, but direct evidence rare. This study aims to examine structural abnormalities adolescents with SAD. Methods High-resolution T1-weighted images were obtained from 31 (15–17 years) 42 matching healthy controls (HC). We evaluated symptom severity Anxiety...
Introduction: The pathological progression of non-alcoholic fatty liver disease (NAFLD) is driven by multiple factors, and steatohepatitis (NASH) represents its progressive form. In our previous studies, we found that bicyclol had beneficial effects on NAFLD/ NASH. Here aim to investigate the underlying molecular mechanisms effect NAFLD/NASH induced high-fat diet (HFD) feeding. Methods: A mice model HFD-feeding for 8 weeks was used. As a pretreatment, (200 mg/kg) given oral gavage twice...
Introduction Infected pancreatic necrosis (IPN) and its related septic complications are the major causes of death in patients with acute necrotising pancreatitis (ANP). Therefore, prevention IPN is great clinical value, immunomodulatory therapy thymosin alpha 1 may be beneficial. This study was designed to test hypothesis that administration during phase ANP will result a reduced incidence IPN. Methods analysis randomised, multicentre, double-blind, placebo-controlled study. 520 eligible...
Gu‑Ben‑Fang‑Xiao‑Tang (GBFXT) is a traditional Chinese medicine formula consisting of 11 medicinal plants, which has been used in the treatment asthma. The present study aimed to determine protective effects and underlying mechanisms GBFXT on ovalbumin (OVA)‑induced allergic inflammation mouse model A total 50 mice were randomly assigned following five experimental groups: Normal, model, montelukast (2.6 mg/kg), 12 g/kg 36 groups. Airway responsiveness was measured using forced oscillation...
Abstract Background and objective: Anaemia commonly aggravates the severity of respiratory diseases, whereas thus far, no study has elucidated impact anaemiaonCorona Virus Disease 2019(COVID-19). The aim this was to evaluate clinical characteristics patients with anaemia, further explore relationship between anaemiaand COVID-19. METHODS: In single-center, retrospective, observational study, a total 222 were recruited, including 79 anaemia 143 without anaemia. Clinical characteristics,...
Background: This study aimed to summarize the clinicopathological features and prognostic risk factors of primary antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in children. Methods: Clinical data for children admitted our center with AAV between September 2003 2020 were studied retrospectively. The incidence end-stage renal disease (ESRD) calculated analyzed. Results: Thirty-four enrolled; 28 female, a median onset age 10 years. Except one case negative ANCA, other...
Abstract: Although inflammation plays an important role in myocardial ischemia/reperfusion injury (MI/RI), anti-inflammatory treatment with a single target has little clinical efficacy because of the multifactorial disorders involved MI/RI. MicroRNAs (miR-24) can achieve multitarget regulation several diseases, suggesting that this factor may have ideal effects on alleviation In present study, bioinformatics method was used to screen potential therapeutic targets miR-24 associated Three days...
Background: A transcutaneous bilirubin meter has been regarded as an effective screening tool for neonatal hyperbilirubinemia, even in pigmented neonates. Objectives: This study is designed to evaluate the accuracy of a meter, namely Konica Minolta Air-Shields JM-103, Taiwanese neonates, and examine effectiveness JM-103 reducing frequency blood sampling necessary newborn babies. Method: Transcutaneous (TcB) measurements via were performed within one hour before or after total serum (TsB)....