A5101990222- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Lipid metabolism and disorders
- Liver Disease Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Clinical Nutrition and Gastroenterology
- Pediatric Hepatobiliary Diseases and Treatments
- Electrolyte and hormonal disorders
- Dermatological and COVID-19 studies
- Hip and Femur Fractures
- Esophageal and GI Pathology
- Appendicitis Diagnosis and Management
- Diabetes and associated disorders
- Bone fractures and treatments
- Esophageal Cancer Research and Treatment
- Renal function and acid-base balance
- Pituitary Gland Disorders and Treatments
- Diet, Metabolism, and Disease
- Abdominal Trauma and Injuries
- Sepsis Diagnosis and Treatment
- Respiratory and Cough-Related Research
- Antifungal resistance and susceptibility
- Nutrition and Health in Aging
- Liver Disease and Transplantation
- Gastric Cancer Management and Outcomes
Southern Medical University
2021-2025
Nanjing Medical University
2020-2025
Nanjing General Hospital of Nanjing Military Command
2010-2025
Nanjing University
2020-2025
Baoding People's Hospital
2022-2024
Baoding No.1 Central Hospital
2023-2024
Soochow University
2024
Renmin Hospital of Wuhan University
2024
First Affiliated Hospital of Soochow University
2024
Wuhan University
2024
Metabolic associated fatty liver disease (MAFLD) is diagnosed in patients with hepatic steatosis when they have the following three metabolic conditions: obesity/overweight, diabetes and dysregulation, either alone or combination. There no clarity whether subtypes of MAFLD by different conditions carry levels risk for intra- extra-hepatic organs. This study aims to depict characteristics these a large population.The data were retrieved from third National Health Nutrition Examination Surveys...
The incidence of hypertriglyceridemia-associated acute pancreatitis (HTG-AP) is increasing. Plasmapheresis theoretically effective in removing triglyceride from plasma, but whether it confers clinical benefits unclear.To assess the association between plasmapheresis and duration organ failure among patients with HTG-AP.This an a priori analysis data multicenter, prospective cohort study enrolled 28 sites across China. Patients HTG-AP were admitted within 72 hours disease onset. first patient...
Non-invasive hepatic steatosis algorithms are recommended in detecting metabolic-associated fatty liver disease (MAFLD) epidemiological studies. However, the diagnostic accuracy of these models is unclear. This study aimed to evaluate efficiency five common a national survey population.The Third National Health and Nutrition Examination Survey (NHANES III) datasets were used this study. The index (FLI), (HSI), non-alcoholic disease-liver fat score (NAFLD-LFS), steato text (ST), visceral...
An effective and safe treatment for nausea vomiting of pregnancy (NVP) is lacking.
No specific triglyceride-lowering therapy is recommended in patients with hypertriglyceridemia-associated acute pancreatitis (HTG-AP), primarily because of the lack quality evidence. This study aimed to describe practice variations therapies for early HTG-AP and assess whether more rapid triglyceride decline associated improving organ failure. a multicentre, prospective cohort recruiting elevated plasma (> 11.3 mmol/L) admitted within 72 h from onset symptoms. Patients were dichotomised on...
Abstract This study investigated the genetic basis of spontaneous intraabdominal hemorrhage (SIH) in severe acute pancreatitis (SAP) to facilitate development more effective treatments for this life‐threatening complication. A four‐phase was conducted with a large cohort (AP) patients ( n = 600). In first phase, whole‐exome sequencing identified specific exonic variant (rs1326680184) human Fc gamma binding protein FCGBP ) gene consistently associated SIH. The second phase employed serum...
Abstract Background Malnutrition due to interruption of enteral nutrition remains a prevalent issue in the intensive care unit (ICU). Aim This study aimed determine frequency and causes (ENI)and its impact on implementing nutrition. Study Design is secondary analysis multicentre, cluster‐randomized controlled trial ( N = 2772). included patients ICU for at least 72 h receiving total The ENI were defined as (1) feeding intolerance, (2) diagnostic therapeutic procedures (3) others. Multiple...
The relationship between vitamin D levels and non-alcoholic fatty liver disease (NAFLD) remains unestablished. In this study, we aimed to explore the NAFLD based on population survey data. This cross-sectional study was conducted data from National Health Nutrition Examination Survey. Liver steatosis diagnosed by ultrasonography. Binary logistic regression analyses were performed determine status NAFLD. A total of 9,782 participants identified in analysis, with 46.8% male an average age...
Previous studies have shown that minimally invasive treatment for infected necrotizing pancreatitis (INP) may be safer and more effective than open necrosectomy (ON), but ON is still irreplaceable in a portion of INP patients. Furthermore, there lack tools to identify patients at risk step-up approach failure (eventually received or died), which enable appropriate them. Our study aims factors can predict develop nomogram early prediction. Multivariate logistic regression was performed...
To compare the effect of balanced multielectrolyte solutions (BMESs) versus normal saline (NS) for intravenous fluid on chloride levels and clinical outcomes in patients with predicted severe acute pancreatitis (pSAP). Isotonic crystalloids are recommended initial therapy pancreatitis, but whether use BMES preference to NS confers benefits is unknown. In this multicenter, stepped-wedge, cluster-randomized trial, we enrolled pSAP (acute physiology chronic health evaluation II score ≥8...
Background Coronary CT-derived fractional flow reserve (CT-FFR) has been used in patients with suspected coronary artery disease (CAD); however, whether it decreases invasive angiography (ICA) use and affects prognosis remains insufficiently evidenced. Purpose To explore the effectiveness of adding CT-FFR to routine CT (CCTA) on short-term ICA rate major adverse cardiovascular events (MACE) a Chinese setting. Materials Methods A multicenter randomized controlled trial was conducted 17...
Invasive pulmonary aspergillosis (IPA) is increasingly reported in chronic obstructive disease (COPD) patients. These patients often have poor clinical outcomes. Early recognition of IPA COPD always challenging. We aimed to develop and validate a risk model using readily available parameters predict for acute exacerbation (AECOPD) patients.We performed retrospective cohort study. AECOPD who were admitted Jinling Hospital between January 2012 December 2017 included. 880 randomly divided into...
Background: Acute pancreatitis (AP) is a potentially life-threatening inflammatory disease with multiple etiologies. The prevalence of hypertriglyceridemia-induced acute (HTG-AP) has been increasing in recent years. It reported that early triglyceride (TG) levels were associated the severity disease, and TG- lowering therapies, including medical treatment blood purification, may impact clinical outcomes. However, there no consensus regarding optimal TG-lowering therapy, practice varies...
This study aimed to compare the biomechanical performance of various cage positions in stand-alone lateral lumbar interbody fusion(SA LLIF).An intact finite element model L3-L5 was reconstructed. The verified and analyzed. Through changing position cage, SA LLIF established four directions: anterior placement(AP), middle placement(MP), posterior placement(PP), oblique placement(OP). A 400 N vertical axial pre-load imposed on superior surface L3 a 10 N/m moment applied along radial direction...
Abstract Objectives Infected pancreatic necrosis (IPN) is a significant complication of acute necrotizing pancreatitis (ANP). Early identification patients at high risk IPN would enable appropriate treatment, but there lack valid tools. This study aimed to assess the performance Pancreatitis Activity Scoring System (PASS) and its modifications (by removing or reducing weight opioid usage) in predicting cohort predicted severe ANP patients. Methods Data was prospectively collected TRACE trial...
Abstract Background Plasmapheresis is widely used for severe hypertriglyceridemia-associated acute pancreatitis (HTG-AP) to remove excessive triglycerides from plasma. This study aimed evaluate whether plasmapheresis could improve the duration of organ failure in HTG-AP patients. Methods We analyzed a cohort patients multicenter, prospective, long-running registry (the PERFORM) collecting admitted sites within 72 h onset symptoms. was based on data collected November 2020 March 2023....
Abstract Background As an innovative internal fixation system, FNS (femoral neck system) is increasingly being utilized by surgeons for the treatment of femoral fractures. At present, there have been numerous finite element analysis experiments studying immediate stability and CSS in treating However, scarce mechanical available regarding effects post removal. This study aimed to investigate alterations parameters proximal femur before after removal system), assess potential distinctions...
<title>Abstract</title> Severe Acute Pancreatitis (SAP) is an acute, severe, and high-mortality special type of pancreatitis, often accompanied by gut microbiota disorders. Gut its derived metabolites are involved in SAP progression, but microbial metabolism their roles remain unclear. In this study, we found that homeostasis was imbalanced SAP, especially the increase lipids decrease carbohydrate & amino acid metabolism, which were reversed depleting microbiota. Trehalose significantly...