A5101755798- Liver Disease Diagnosis and Treatment
- Traditional Chinese Medicine Studies
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Disease and Adiposity
- Liver Disease and Transplantation
- Neurological Disease Mechanisms and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Acupuncture Treatment Research Studies
- Blood Pressure and Hypertension Studies
- Cardiovascular Function and Risk Factors
- Lipoproteins and Cardiovascular Health
- Diabetes Management and Research
- Cardiac electrophysiology and arrhythmias
- Hepatitis B Virus Studies
- Metabolism, Diabetes, and Cancer
- Anesthesia and Sedative Agents
- Diabetes and associated disorders
- MicroRNA in disease regulation
- Coronary Interventions and Diagnostics
- Cancer-related molecular mechanisms research
- Venous Thromboembolism Diagnosis and Management
- Heart Rate Variability and Autonomic Control
- Adipokines, Inflammation, and Metabolic Diseases
- Organ Transplantation Techniques and Outcomes
- Thyroid and Parathyroid Surgery
First Affiliated Hospital of Wannan Medical College
2023-2025
Shanghai Jiao Tong University
2009-2025
Shanghai First People's Hospital
2025
First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
2016-2024
Sichuan University
2010-2024
Nanjing University of Chinese Medicine
2020-2024
Institute of Geographic Sciences and Natural Resources Research
2024
West China Second University Hospital of Sichuan University
2023-2024
Ningbo Institute of Industrial Technology
2024
Chinese Academy of Sciences
2024
Tanshinone IIA (Tan IIA) is effective in the treatment of inflammation and atherosclerosis. The adhesion inflammatory cells to vascular endothelium plays important role atherogenic processes. This study examined effects Tan on expression molecules tumor necrosis factor-α (TNF-α)-induced endothelial progenitor (EPCs).EPCs were pretreated with stimulated TNF-α. Mononuclear cell (MNC) assay was performed assess TNF-α-induced MNC adhesion. Expression molecule-1 (VCAM-1)/intracellular (ICAM-1)...
Gestational diabetes mellitus (GDM) is associated with an increased risk of metabolic disorders in offspring later life. Although mounting evidence suggests that therapy for GDM could improve neonatal health, whether the confers long-term benefits to their adult lives not known. Here, using a mouse model latter half pregnancy mimic human GDM, we find efficient insulin significant protection against glucose intolerance and obesity fed normal chow diet. However, fails protect when challenged...
Abstract Globally, cases of myopia have reached epidemic levels. High and pathological (PM) are the leading cause visual impairment blindness in China, demanding a large volume screening tasks to control rapid growing myopic prevalence. It is desirable develop automatically intelligent system facilitate these time- labor- consuming tasks. In this study, we designed series deep learning systems detect PM macular lesions according recent international photographic classification (META-PM)...
Abstract Terrestrial ecosystems play a pivotal role in the global carbon sequestration process, and their photosynthetic capacity is highly susceptible to fluctuations climate conditions. In 2022, Yangtze River Basin (YRB) China experienced an extensive severe compounded heat drought event. Compared with past two decades, our results revealed that temperature increased by approximately 0.78 ± 0.45 °C precipitation decreased about 45.20 30.10 mm from July October 2022 over whole YRB. Region I...
Osteoporosis, a prevalent metabolic bone disease affecting millions worldwide. Although MS-275 has been reported to inhibit oxidative stress, its ability protect osteoblasts from stress damage yet be clarified. This study investigated whether can and promote osteogenesis by activating the miRNA-200a/Keap1/Nrf2 signaling pathway. In vitro, MC3T3-E1 cells underwent induction with carbonyl cyanide 3-chlorophenylhydrazone, leading establishment of an model, investigating underlying mechanism....
Serum neurofilament light chain (sNfL) is one of the most sensitive diagnostic biomarkers for a variety neurodegenerative pathologies. Potassium, an essential electrolyte, plays critical role in maintaining neuronal health and proper functioning central nervous system (CNS). The aim our research was to investigate association between serum potassium level sNfL levels. Based on National Health Nutrition Examination Survey (NHANES) database, we analyzed data from 2013 2014 NHANES....
The purpose of the present study was to evaluate technical feasibility and safety sharp recanalization for central venous occlusive disease (CVOD) in patients requiring hemodialysis.Patients with CVOD hemodialysis who had undergone endovascular using devices, including stiff end a guidewire, Chiba needle, or RUS-100 cross occluded segments after conventional techniques failed were included. needle guided toward target placed at opposite occlusion. Although guidewire passed though occlusion,...
Determine the serum levels of endogenous secretory receptor for advanced glycation end products (esRAGEs) in patients with type 2 diabetes and mild cognitive impairment (MCI) control but no MCI, examine relationship esRAGE MCI other clinical factors.A total 101 who were hospitalized Department Endocrinology at Fujian Provincial Hospital between January 2010 2011 enrolled. There 58 43 without (control). Serum measured using an enzyme-linked immunosorbent assay (ELISA). Other parameters also...
Abstract One of pathological hallmarks Alzheimer's disease (AD) is neurofibrillary tangles (NFTs) consisting abnormally hyperphosphorylated tau. The molecular mechanisms underlying the regulation tau hyperphosphorylation remain largely unclear. phosphoinositide 3‐kinase (PI3K)/Akt pathway has been implicated in pathogenesis AD, however, potential functions and role tumor suppressor phosphatase tensin homologue deleted on chromosome 10 (PTEN) AD have not fully explored. Here, we report that...
Modern lifestyles have altered diet and metabolic homeostasis, with increased sugar intake, glycemic index, prediabetes. A strong positive correlation between consumption diabetic incidence is revealed, but the underlying mechanisms remain obscure. Here we show that oral intake of long-term oscillating glucose (LOsG) (4 times/day) for 38 days, which produces physiological variability in rats, can lead to β-cells gaining memory reactive oxygen species (ROS) stress. This stress leads...
Abstract A novel compact microstrip second‐order lossy bandpass filter (BPF) based on an improved simplified composite right‐/left‐handed zeroth‐order resonator (ISZOR) is presented in this paper. The ISZOR (MISZOR) features miniature topology and ample adjustable physical parameters accompanied by its easily controllable base mode first harmonic. Its layout can be quickly generated applying the implicit space mapping technique. By virtue of coupling matrix synthesis method, finite unloaded...
Hypertension is the most prevalent cardiovascular disease, and various risk factors are known to be involved in it. Cervical spondylotic myelopathy (CSM) common non-traumatic cause of myelopathy, which displays neurological symptoms may induce systemic symptoms. To date, it still unknown whether CSM associated with hypertension, if so, decompression operations can attenuate hypertension. Here, a total 309 patients who received anterior or posterior surgery were enrolled as subjects. Blood...