Weiwei Xiao

ORCID: 0000-0002-5547-3943
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About
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Research Areas
  • Fiber-reinforced polymer composites
  • Polymer crystallization and properties
  • Recycling and Waste Management Techniques
  • Acute Kidney Injury Research
  • Sepsis Diagnosis and Treatment
  • Nanoplatforms for cancer theranostics
  • Hemoglobinopathies and Related Disorders
  • Epoxy Resin Curing Processes
  • Advanced ceramic materials synthesis
  • Metal-Organic Frameworks: Synthesis and Applications
  • Polymer Nanocomposites and Properties
  • Dendrimers and Hyperbranched Polymers
  • Natural Fiber Reinforced Composites
  • MXene and MAX Phase Materials
  • Oral microbiology and periodontitis research
  • Retinoids in leukemia and cellular processes
  • Polymer Nanocomposite Synthesis and Irradiation
  • Inflammatory Biomarkers in Disease Prognosis
  • Alkaloids: synthesis and pharmacology
  • Sulfur-Based Synthesis Techniques
  • Bone Metabolism and Diseases
  • Graphene and Nanomaterials Applications
  • Viral gastroenteritis research and epidemiology
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Ocular Infections and Treatments

Xinjiang Institute of Materia Medica
2024

Xinjiang University
2024

Southwest Medical University
2024

Stomatology Hospital
2024

Hengshui University
2024

Hunan Provincial People's Hospital
2019-2023

General Department of Preventive Medicine
2023

Yuhuangding Hospital
2019-2023

Shenzhen Children's Hospital
2018-2023

Hunan Normal University
2019-2022

Ginsenoside-Rg1 (G-Rg1), a saponin that is primary component of ginseng, effective against inflammatory diseases. The P2X purinoceptor 7 (P2X7) receptor an ATP-gated ion channel predominantly expressed in immune cells and plays key role processes. We investigated the G-Rg1 sepsis-related cardiac dysfunction underlying mechanism involving regulation P2X7 receptor. detected cell viability, cytotoxicity, cellular reactive oxygen species (ROS) levels, mitochondrial membrane potential (MMP) with...

10.1002/jbt.22885 article EN Journal of Biochemical and Molecular Toxicology 2021-12-02

ObjectiveSepsis is the leading course of morbidity and mortality in critically ill patients. This study aimed to evaluate predictive value platelet aggregation for patients with sepsis. In addition, relationship between impaired mitochondria was explored.MethodThis a prospective, observational cohort study. The rate response adenosine diphosphate (ADP) assessed. primary outcome 28-day mortality. Platelet mitochondrial parameters, including triphosphate(ATP), membrane potential (MMP)...

10.1016/j.jinf.2022.02.004 article EN cc-by-nc-nd Journal of Infection 2022-02-09

Abstract The aim of the present study was to identify functional role galectin‐3 (Gal‐3) in lipopolysaccharide (LPS)‐induced injury ATDC5 cells and explore probable molecular mechanisms. Here, we identified that LPS is sufficient enhance expression Gal‐3 cells. In addition, repression obviously impeded LPS‐stimulated inflammation damage as exemplified by a reduction release inflammatory mediators interleukin (IL)‐1β, IL‐6, tumor necrosis factor‐α, well production nitric oxide prostaglandin...

10.1002/jcb.28304 article EN Journal of Cellular Biochemistry 2018-12-19

The curing reactions and formation mechanism of 3D GO network.

10.1039/c6ra16335a article EN RSC Advances 2016-01-01

1,8-Naphthyridone-3-carboxyl is the core structure of several on-market antibacterial drugs. It has prompted significant interest from synthetic community. Here, we report a practical synthesis diversely functionalized 1,8-naphthyridone-3-carboxylic acid derivatives starting readily available and inexpensive nicotinic derivatives. All key steps have been optimized. Furthermore, usefulness this protocol exemplified by first amfonelic acid.

10.1021/acs.joc.4c00415 article EN The Journal of Organic Chemistry 2024-04-11

Glioblastoma multiforme (GBM) is a malignant and aggressive central nervous system (CNS) tumor with high mortality low survival rate. Effective treatment of GMB challenge worldwide. Temozolomide (TMZ) drug used to treat GBM, while the period GBM patients positive remains less than 15 months. Reactivating p53 Inducing Tumor Apoptosis (RITA) novel potential anti-cancer small molecular drug. Thus, it essential discover targets or develop effective drugs combination strategy GBM.The U87 cells...

10.1159/000495923 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2018-01-01

The discovery of broadly neutralizing monoclonal antibodies against influenza viruses has raised hope for the successful development new antiviral drugs. However, due to speed and variety mutations in viruses, single-component that recognize specific epitopes are susceptible viral escape have limited efficacy when administration is delayed. Hence, it necessary develop alternative strategies with better activity. Influenza B virus infection can cause severe illness children elderly. Commonly...

10.1002/jmv.28106 article EN Journal of Medical Virology 2022-08-30

Thyroxine-binding globulin (TBG; the gene product of SERPINA7) is main transporter thyroid hormones in humans. Mutations TBG may lead to inherited deficiency. There have been 28 reported mutations that associate with complete deficiency (TBG-CD). Here we identified a novel frameshift mutation causing early termination protein and TBG-CD Chinese family.A 46-year-old man was referred our hospital normal free thyroxine, triiodothyronine, thyrotropin, but lower total thyroxine undetectable serum...

10.12998/wjcc.v7.i22.3887 article EN World Journal of Clinical Cases 2019-11-26

Abstract Background Peri-implantitis (PI) is a common complication of dental implants that can result in implant failure. The study aims to identify genes related PI and Ferroptosis, analyze relevant molecules pathways, perform immune infiltration analysis, with the goal investigating classification creating diagnostic model using its genes. Methods first identified Ferroptosis-related (FRGs) by downloading datasets GSE33774 GSE57631 intersecting them FRGs set. Enrichment including Gene Set...

10.21203/rs.3.rs-3782755/v1 preprint EN cc-by Research Square (Research Square) 2024-01-09

The development of students' character in higher education is intertwined with the guidance provided by Civic Teachers on values, and school's policy plays a crucial role carrying out essential task building morality fostering individuals. deep integration party bu

10.4108/eai.13-10-2023.2341313 article EN 2024-01-01

Abstract The relationship between spinnability and composition of poly(vinyl alcohol)/polyacrylonitrile block copolymer emulsions prepared by an ultrasonic technique is presented. Theoretical analysis experimental investigation multiple techniques show that the micellar structure characteristics behavior emulsion in shear flowing coagulating spinning process are key factors affecting spinnability. mechanical properties final fibers related to composition, molecular weight, copolymers,...

10.1002/pen.760341205 article EN Polymer Engineering and Science 1994-06-01

To analyze the genotype and hematological characteristics of children with αβ-thalassemia in Shenzhen area China.The erythrocyte parameters hemoglobin components were determined by blood routine examination capillary electrophoresis (CE). Reverse dot blot (RDB) -polymerase chain reaction (PCR) was used to determine gene mutations α- β-thalassemia children. The Gap-PCR deletion α-thalassemia children,while specimens suspected HKαα nested PCR.Total 29 complex genotypes detected from 74 cases...

10.19746/j.cnki.issn.1009-2137.2019.04.039 article EN PubMed 2019-08-01

Typical p-type semiconductor MnO<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mrow><mml:mi>x</mml:mi></mml:mrow></mml:math> codoped with n-type semiconductors such as CeO 2 and V O 5 was reported to achieve high efficiency in catalytic NO<mml:math id="M2"><mml:mrow><mml:mi>x</mml:mi></mml:mrow></mml:math> removal by NH 3 . In this paper, we present novel Mn-Ce /TiO catalyst which exhibited an excellent NO conversion of 90% at 140°C. By using catalyst, the best...

10.1155/2017/7901686 article EN Journal of Nanomaterials 2017-01-01

Abstract Polypropylene/poly(vinyl acetate) (PP/PVAc) (30/70) blend possesses higher thermal stability than PVAc and is stable below 300°C. The viscosity of the lower that PP at 220°C. fibers have sheath‐core morphology; core composed fibrils because has reasonably PVAc. Due to reinforcement fibrils, tensile strength modulus were increased. drawn 50°C possess better mechanical properties those 90°C. © 1994 John Wiley &amp; Sons, Inc.

10.1002/app.1994.070520803 article EN Journal of Applied Polymer Science 1994-05-23

Abstract The moisture content of poly(vinyl alcohol‐ b ‐acrylonitrile) fibers decreases with an increasing hydrophobic AN and crystallinity the fibers; however, copolymer fiber 26.94% AN, drawn × 5, heat‐treated at 200°C has a value slightly lower than that commercial PVA fiber, but much higher PAN fiber. block have water‐retention owing to presence voids in these fibers, stronger wicking ability PVA, wool cotton mainly due grooved surface bulk porous morphology fibers. tensile strength...

10.1002/app.1181 article EN Journal of Applied Polymer Science 2001-03-02

To explore the coincidence rate of G-banding karyotype analysis and fluorescence in situ hybridization (FISH) for diagnosis children with sex chromosome mosaicisms.A retrospective was carried out 157 suspected abnormalities who had presented at Shenzhen Children's Hospital from April 2021 to May 2022. Interphase FISH karyotyping results were collected. The two methods mosaicisms compared.The detection rates 26.1% (41/157) 22.9% (36/157) , respectively (P > 0.05). showed that 141 cases...

10.3760/cma.j.cn511374-20211111-00897 article EN PubMed 2023-01-10
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