A5101663349- Emergency and Acute Care Studies
- Cardiac Arrest and Resuscitation
- Disaster Response and Management
- Immune Cell Function and Interaction
- Sepsis Diagnosis and Treatment
- Inflammasome and immune disorders
- Trauma and Emergency Care Studies
- Acute Kidney Injury Research
- COVID-19 and Mental Health
- Venomous Animal Envenomation and Studies
- T-cell and B-cell Immunology
- Respiratory Support and Mechanisms
- Resilience and Mental Health
- Adenosine and Purinergic Signaling
- Advanced battery technologies research
- Long-Term Effects of COVID-19
- Eicosanoids and Hypertension Pharmacology
- Bullying, Victimization, and Aggression
- Inflammatory Biomarkers in Disease Prognosis
- Medical Education and Admissions
- Porphyrin Metabolism and Disorders
- Rabies epidemiology and control
- Caveolin-1 and cellular processes
- RNA modifications and cancer
- RNA Research and Splicing
Beijing Chao-Yang Hospital
2024-2025
Capital Medical University
2022-2025
Chongqing University
2022-2024
Hunan Provincial People's Hospital
2011-2024
Hunan Normal University
2018-2024
Hunan Provincial Center for Disease Control and Prevention
2024
Clinical Research Institute
2022
Beijing Friendship Hospital
2022
National Clinical Research Center for Digestive Diseases
2022
Sungkyunkwan University
2022
Abstract The practical application of lithium–sulfur batteries (LSBs) is limited by the shuttle effect lithium polysulfides (LiPSs), large volume expansion, and sluggish conversion kinetics sulfur. Herein, crystallinity regulation Ni x Fe y alloy anchored on oxidized carbon nanotube/nitrogen‐doped graphene (Ni @OCNT/NG) for a functional separator into LSBs demonstrated. A low crystalline @OCNT/NG (LC‐Ni modified polypropylene systematically compared with its highly counterpart (HC‐Ni...
The durability of infection-induced severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity has crucial implications for reinfection and vaccine effectiveness. However, the relationship between disease 2019 (COVID-19) severity long-term anti-SARS-CoV-2 immunoglobulin G (IgG) antibody level is poorly understood. Here, we measured longevity SARS-CoV-2-specific IgG antibodies in survivors who had recovered from COVID-19 1 year previously. In a cohort 473 with varying...
Ginsenoside-Rg1 (G-Rg1), a saponin that is primary component of ginseng, effective against inflammatory diseases. The P2X purinoceptor 7 (P2X7) receptor an ATP-gated ion channel predominantly expressed in immune cells and plays key role processes. We investigated the G-Rg1 sepsis-related cardiac dysfunction underlying mechanism involving regulation P2X7 receptor. detected cell viability, cytotoxicity, cellular reactive oxygen species (ROS) levels, mitochondrial membrane potential (MMP) with...
ObjectiveSepsis is the leading course of morbidity and mortality in critically ill patients. This study aimed to evaluate predictive value platelet aggregation for patients with sepsis. In addition, relationship between impaired mitochondria was explored.MethodThis a prospective, observational cohort study. The rate response adenosine diphosphate (ADP) assessed. primary outcome 28-day mortality. Platelet mitochondrial parameters, including triphosphate(ATP), membrane potential (MMP)...
In-hospital cardiac arrest (IHCA) is a common clinical event with poor outcomes. Former IHCA registries in China were local, inconsistent data reporting, and lacked attention to the process of care. Therefore, we designed implemented BASeline Investigation Cardiac Arrest (BASIC-IHCA), first national registry China.BASIC-IHCA prospective, multicenter, observational study nationwide surveillance network covering urban rural hospitals from seven geographic regions China. patients enrolled...
A magnetically recoverable biocatalyst has been effectively prepared through the immobilization of α-amylase onto Fe3O4 nanoparticles. The magnetic nanoparticles (MNPs) were synthesized by a sol–gel method in an aqueous system. MNPs' surfaces modified with sodium silicate and 3-aminopropyltriethoxysilane (APTS). adsorptive was attempted APTS–SiO2–Fe3O4 physicochemical properties biocatalysts characterized Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM),...
Abstract Background Psoriasis is a chronic immune-mediated skin condition. Although biologic treatments are effective in controlling psoriasis, some patients do not respond or lose response to these therapies. Thus, new strategies for psoriasis treatment still urgently needed. Double-negative T cells (DNT) play significant immunoregulatory role autoimmune diseases. In this study, we aimed evaluate the protective effect of DNT and explore underlying mechanism. Methods We conducted single...
Abstract Background This study aimed to investigate attitudes towards health education on snakebites and identify the influencing factors among Chinese residents. Additionally, we proposed effective strategies for snakebite management. Methods Between May 2022 February 2023, conducted a nationwide cross-sectional questionnaire survey using multistage sampling method with supplementary snowball sampling. We used descriptive analysis, χ2 tests, univariable multivariable binary logistic...
Objective To evaluate the beneficial effects of hydroxysafflor yellow A (HSYA) on monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH) in rats, and to investigate main pathophysiological mechanism HSYA preventing development MCT-induced PAH. Methods Four groups (control, control with treatment, MCT-exposed, MCT-exposed treatment) were evaluated at day 28 following MCT exposure. Haemodynamic measurements, right ventricular hypertrophy, morphometry, inflammatory cytokines oxidant...
We aim to understand the current situation of first aid ability and training needs Chinese medical personnel provide a scientific basis for formulating contents methods emergency rescue thereby improve level personnel.A cross-sectional survey was conducted between June 2022 February 2023 using two-stage cluster sampling method with structured questionnaire sent workers in 12 provinces China. 14,527 questionnaires were included this study. Data collected on demographic characteristics,...
The intestine is one of the main target organs involved in pathological process heatstroke. CCAAT/enhancer-binding protein homologous (CHOP) endoplasmic reticulum (ER) stress-induced apoptosis. This study aimed to explore role CHOP heatstroke-induced intestinal injury and potential therapy. An vitro heat stress (HS) model using Caco-2 cells was employed. We observed apoptosis-mediated epithelial cell secondary HS by evaluating viability, lactate dehydrogenase release, apoptosis levels,...
Acute respiratory distress syndrome (ARDS) is the inflammatory disorder of lung most commonly caused by sepsis. It was hypothesized that treating with penehyclidine hydrochloride (PHC), a new type hyoscyamus drug, early in development sepsis could diminish dysfunction.Sprague-Dawley rats were divided into 4 groups: 1) control group; 2) sham-operated 3) cecal ligation and puncture (CLP) 4) PHC-treated group. One hour after CLP surgery, either untreated or treated PHC via intraperitoneal...
Background: By investigating the incidence of post-traumatic stress disorder (PTSD) among residents during a period low transmission, this study reflects long-term impact coronavirus disease 2019 (COVID-19) and identify which categories are more likely to develop PTSD due an acute infectious crisis, facilitating development targeted strategies protect mental health after outbreaks similar diseases in future. Methods: A cross-sectional survey was conducted China from 4 26 February 2021....
Heat stroke (HS) is an acute physical illness associated with a higher risk of organ dysfunction. This study the first to explore exosomal miR-548x-3p derived from human bone marrow mesenchymal stem cells (BMSCs) in pyroptosis vascular endothelial (VECs) HS. Human BMSCs-derived exosome alleviated injury heart, liver, kidney and ileum tissues, increase IL-1β, IL-18 TNF-α levels, HGMB1, NLRP3, ASC, caspase1 GSDMD-N protein expression HS mice HS-induced umbilical vein (HUVECs). was...
The Quick Sequential Organ Failure Assessment (qSOFA) score proposed by Sepsis-3 as a sepsis screening tool has shown suboptimal accuracy. Heparin-binding protein (HBP) been to identify early with high Herein, we aim investigate whether or not HBP improves the model performance of qSOFA.We conducted multicenter prospective observational study 794 adult patients who presented emergency department (ED) presumed between 2018 and 2019. For each participant, serum levels were measured hospital...
Abstract Hexagonal boron nitride (BN), a well‐known member of 2D materials, has structure similar to graphene and is often referred as white graphene. Despite its unique physical chemical properties for energy storage applications, there have been very few studies on how BN stores anion carriers. Herein, the hybrid architecture mechanism nanosheets high‐performance full cells based dual‐ion Zinc (Zn) alkaline systems demonstrated. The bonding between reduced oxide (rGO) attributed formation...
Background: Burnout is considered a global problem, particularly in the emergency health sector; however, no large-sample cross-sectional study has assessed prevalence of burnout among physicians and its associated factors. Methods: A nationally representative survey 15,243 was conducted 31 provinces across China between July September 2019. Multiple linear regression analysis performed to identify correlates burnout. Results: The participants' mean scores were 25.8 (SD = 15.9) on emotional...