A5002050547- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Bone health and treatments
- Gout, Hyperuricemia, Uric Acid
- Autoimmune and Inflammatory Disorders Research
- COVID-19 Clinical Research Studies
- Sarcoidosis and Beryllium Toxicity Research
- Dermatological and COVID-19 studies
- Management of metastatic bone disease
- Systemic Sclerosis and Related Diseases
- Case Reports on Hematomas
- Medical Imaging Techniques and Applications
- Vasculitis and related conditions
- Bone and Joint Diseases
- Parathyroid Disorders and Treatments
- Telomeres, Telomerase, and Senescence
- Hematological disorders and diagnostics
- Transplantation: Methods and Outcomes
- Oral Health Pathology and Treatment
- Inflammatory Myopathies and Dermatomyositis
- Long-Term Effects of COVID-19
- Ultrasound in Clinical Applications
- Medical Imaging and Pathology Studies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
Hôpital Bichat-Claude-Bernard
2017-2025
Assistance Publique – Hôpitaux de Paris
2017-2025
Université Claude Bernard Lyon 1
2020-2025
Université Paris Cité
2017-2025
Sorbonne Paris Cité
2017-2024
Délégation Paris 7
2017-2024
Inserm
2020
University of Colorado Denver
2018
Hôpital Lariboisière
2017
Given the phenotypic similarities between rheumatoid arthritis (RA)–associated interstitial lung disease (ILD) (hereafter, RA-ILD) and idiopathic pulmonary fibrosis, we hypothesized that strongest risk factor for development of gain-of-function MUC5B promoter variant rs35705950, would also contribute to ILD among patients with RA.
Patients at high risk of rheumatoid arthritis-associated interstitial lung disease (RA-ILD) would benefit from being identified before the onset respiratory symptoms; this can be done by screening patients with use chest high-resolution computed tomography (HRCT). Our objective was to develop and validate a score for who have subclinical RA-ILD.
We aimed to determine the ability of ultrasonography (US) show disappearance urate deposits in gouty patients requiring urate-lowering therapy (ULT).We performed a 6-month multicentre prospective study including with: proven gout; presence US features gout (tophus and/or double contour sign) at knee first metatarsophalangeal joints; and no current ULT. evaluations were baseline months 3 6 (M3, M6) after starting Outcomes were: change M6 according final (M6) serum (SU) level (high, > 360...
Interstitial lung disease (ILD) is a common complication of rheumatoid arthritis (RA) usually diagnosed with high-resolution CT (HRCT), but emerging data suggest the interest ultrasonography (LUS) for screening RA-ILD. This study aimed to determine ability LUS screen ILD in RA. was an observational monocenter RA patients. All patients underwent pulmonary and rheumatology clinical evaluation, immunology screening, HRCT LUS, function tests (PFTs). US assessment occurred same day as HRCT,...
To develop and evaluate the performance of multicriteria decision analysis (MCDA)-driven candidate classification criteria for antisynthetase syndrome (ASSD). A list variables associated with ASSD was developed using a systematic literature review then refined into an key domains by myositis interstitial lung disease (ILD) experts. This used to create preferences surveys in which experts were presented pairwise comparisons clinical vignettes asked select case that more likely represent ASSD....
Autoimmune/inflammatory rheumatic diseases (AIRDs) patients might be at-risk of severe COVID-19. However, whether this is linked to the disease or its treatment difficult determine. This study aimed identify factors associated with occurrence COVID-19 in AIRD and evaluate having an was increased risk death.Two databases were analyzed: EDS (Entrepôt des Données de Santé, Clinical Data Warehouse), including all followed Paris university hospitals French multi-center cohort [French...
https://bit.ly/3vfPn4k.
Recently, a genome-wide association study identified an between RA-associated interstitial lung disease (ILD) and
Significant bone loss occurs after heart transplantation, predominantly in the first year, with increased risk of incident fractures. The goal this study was to evaluate prevalence fragility fractures a population transplantation patients and identify independent factors for fractures.This prospective monocentric that included occurring < 10 years who were undergoing monitoring. All underwent mineral density evaluation by dual-energy X-ray absorptiometry radiographies establish presence...
"Spontaneous resolution of Epstein-Barr virus-induced haemophagocytic lymphohistiocytosis in Still’s disease treated by tocilizumab: a case report." Scandinavian Journal Rheumatology, 47(1), pp. 84–85
Abstract Objective US of salivary glands (SGUS) is a non-invasive tool that allows for diagnosing primary SS (pSS) or secondary (sSS). However, little known about the prevalence findings in other CTDs. The aim this multi-centre observational study was to evaluate, CTD patients with without SS, abnormal SGUS and possible association clinical biological phenotypes. Methods B-Mode performed by one operator blinded data. Each SG semi-quantitatively rated on scale from 0 4 according Jousse-Joulin...
Objective: Due to the similarities between rheumatoid arthritis-associated interstitial lung disease (RA-ILD) and idiopathic pulmonary fibrosis (IPF), we aimed investigate contribution of rare variants in telomere related genes (TRGs) risk RA-ILD IPF.Methods: For RA-ILD, this genetic case-control association study consisted a derivation replication sample that included cases with controls RA without ILD (RA-noILD). IPF, IPF were compared healthy controls. Whole-exome sequencing was performed...