- Functional Brain Connectivity Studies
- Olfactory and Sensory Function Studies
- Neural dynamics and brain function
- Genetics, Bioinformatics, and Biomedical Research
- Animal testing and alternatives
- Advanced Neuroimaging Techniques and Applications
- Biomedical and Engineering Education
- Vagus Nerve Stimulation Research
- Heart Rate Variability and Autonomic Control
- Memory and Neural Mechanisms
- Neuroscience and Neuropharmacology Research
- Neuroscience of respiration and sleep
- Neuroendocrine regulation and behavior
- EEG and Brain-Computer Interfaces
- Biotechnology and Related Fields
- Neurobiology and Insect Physiology Research
- Action Observation and Synchronization
- Innovation, Technology, and Society
- Thermoregulation and physiological responses
- Psychosomatic Disorders and Their Treatments
- Advanced MRI Techniques and Applications
- Primate Behavior and Ecology
- Neonatal and fetal brain pathology
- Health, Environment, Cognitive Aging
- Veterinary Pharmacology and Anesthesia
Nathan Kline Institute for Psychiatric Research
2022-2024
University Medical Center of the Johannes Gutenberg University Mainz
2020-2024
Johannes Gutenberg University Mainz
2020-2024
Yobe State University
2024
Max Planck Institute for Biological Cybernetics
2015-2023
University of Tübingen
2020-2023
Bernstein Center for Computational Neuroscience Tübingen
2021
Central Institute of Mental Health
2020-2021
Heidelberg University
2020-2021
University Hospital Heidelberg
2021
Digitized neuroanatomical atlases that can be overlaid onto functional data are crucial for localizing brain structures and analyzing networks identified by neuroimaging techniques. To aid in structural analysis, we have created a comprehensive parcellation of the rhesus macaque subcortex using high-resolution ex vivo imaging scan. This anatomical scan its were warped to updated NIMH Macaque Template (NMT v2), an population template, where was refined produce Subcortical Atlas Rhesus (SARM)...
Neuroimaging non-human primates (NHPs) is a growing, yet highly specialized field of neuroscience. Resources that were primarily developed for human neuroimaging often need to be significantly adapted use with NHPs or other animals, which has led an abundance custom, in-house solutions. In recent years, the global NHP community made significant efforts transform towards more open and collaborative practices. Here we present PRIMatE Resource Exchange (PRIME-RE), new online platform...
The vagus nerve, a core component of the parasympathetic nervous system, mediates information transfer between body’s internal milieu and brain. This nerve can be stimulated non-invasively at ear using transcutaneous auricular stimulation (taVNS). Concurrent functional magnetic resonance imaging (fMRI) permits study taVNS-induced changes in brain dynamics, key requisite for precision neurostimulation. To date, however, there is no standardized protocol how to safely apply taVNS during MRI....
The vagus nerve projects to a well-defined neural circuit via the nucleus tractus solitarii (NTS) and its stimulation elicits wide range of metabolic, neuromodulatory, behavioral effects. Transcutaneous (tVNS) has been established as promising technique non-invasively alter brain function. However, precise dynamics elicited by tVNS in humans are still largely unknown. Here, we performed fMRI with concurrent right-sided (vs. sham) following randomized cross-over design (N = 40). First,...
Identifying the circuits responsible for cognition and understanding their embedded computations is a challenge neuroscience. We establish here hierarchical cross-scale approach, from behavioral modeling fMRI in task-performing mice to cellular recordings, order disentangle local network contributions olfactory reinforcement learning. At mesoscale, identifies functional olfactory-striatal interacting dynamically with higher-order cortices. While primary cortices respectively contribute only...
Social recognition is essential for the formation of social structures. Many times, comes with lesser exploration familiar animals. This has led to assumption that may be a habituation memory. The underlying memory mechanisms and thereby acquired cortical representations mice have remained largely unknown, however. Here, we introduce an approach directly examining process from volatile body odors among male mice. We show emitted by are sufficient identify individuals more salience assigned...
Ecological chemosensory stimuli almost always evoke responses in more than one sensory system. Moreover, any processing takes place along a hierarchy of brain regions. So far, the field neuroimaging is dominated by studies that examine role regions isolation. However, to completely understand neural chemosensation, we must also interactions between In general, use connectivity methods has increased field, providing important insights physical processing, such as vision, audition, and touch....
Abstract Digitized neuroanatomical atlases are crucial for localizing brain structures and analyzing functional networks identified by magnetic resonance imaging (MRI). To aid in MRI data analysis, we have created a comprehensive parcellation of the rhesus macaque subcortex using high-resolution ex vivo structural scan. The scan its were warped to updated NIMH Macaque Template (NMT v2), an population template, where was refined produce Subcortical Atlas Rhesus (SARM). subcortical...
<title>Abstract</title> Recent efforts to chart human brain growth across the lifespan using large-scale MRI data have provided reference standards for development. However, similar models nonhuman primate (NHP) are lacking. The rhesus macaque, a widely used NHP in translational neuroscience due its similarities anatomy, phylogenetics, cognitive, and social behaviors humans, serves as an ideal model. This study aimed create normative charts structure macaque lifespan, enhancing our...
Our goal in this manuscript is to advance the assessment and treatment of monkey species neuroscience research. We hope begin a discussion establish baseline data on how complications are identified treated. surveyed research community working with monkeys compiled responses questions about investigator demographics, animal wellbeing, choices, approaches mitigate risks associated CNS procedures promote health wellbeing. The majority respondents had worked nonhuman primates (NHP) for over 15...
Event Abstract Back to Topographic mapping of the primate primary interoceptive cortex Renée Hartig1, 2, 3*, Ceren Battal4, Gianfranco Chávez1, 3, Ana Vedoveli1, Thomas Steudel2, Eduard Krampe2, Axel Öltermann2, Joachim Werner2, Nikos K. Logothetis2, 5 and Henry Evrard1, 2 1 Werner Reichardt Centrum für Integrative Neurowissenschaften (CIN), Germany Max Planck Institute for Biological Cybernetics, 3 International Research School, 4 Scuola di dottorato in Cognitive Brain Sciences, Italy...
SUMMARY The unbiased identification of brain circuits responsible for behavior and their local cellular computations is a challenge neuroscience. We establish here hierarchical cross-scale approach from behavioral modeling fMRI in task-performing mice to network dynamics identify how reward predictions are represented the forebrain upon olfactory conditioning. identified functional segregation prediction error among cortices subcortical circuits. Among them, tubercle contributed both dynamic...
Abstract The vagus nerve projects to a well-defined neural circuit via the nucleus tractus solitarii (NTS) and its stimulation elicits wide range of metabolic, neuromodulatory, behavioral effects. Transcutaneous (tVNS) has been established as promising technique non-invasively alter brain function. However, precise dynamics elicited by tVNS in humans are still largely unknown. Here, we performed fMRI with concurrent right-sided (vs. sham) following randomized cross-over design ( N =40)....
Macroscopic taste processing connectivity was investigated using functional magnetic resonance imaging during the presentation of sour, salty, and sweet tastants in anesthetized macaque monkeys. This examination affords opportunity to study interactions between sensory regions, central integrators, effector areas. Here, 58 brain regions associated with gustatory primates were aggregated, collectively forming connectome. Regional regression coefficients (or β-series) obtained stimulation...
African science has substantial potential, yet it grapples with significant challenges. Here we describe the establishment of Biomedical Science Research Centre (BioRTC) in Yobe State, Northeast Nigeria, as a case study hub fostering on-continent research and strategies to surmount some these barriers. We detail steps taken establish BioRTC, emphasising critical importance stakeholder engagement, community involvement, resource optimisation, collaborations. Although are early stages our...