A5101405855- Ion Channels and Receptors
- Advanced biosensing and bioanalysis techniques
- Cancer Mechanisms and Therapy
- Hydrogen's biological and therapeutic effects
- Effects and risks of endocrine disrupting chemicals
- Quinazolinone synthesis and applications
- ATP Synthase and ATPases Research
- Reproductive Biology and Fertility
- Cardiovascular Health and Disease Prevention
- MicroRNA in disease regulation
- Genomics, phytochemicals, and oxidative stress
- PI3K/AKT/mTOR signaling in cancer
- Metabolomics and Mass Spectrometry Studies
- Medical and Biological Ozone Research
- Neurogenetic and Muscular Disorders Research
- Trace Elements in Health
- Chemical Reactions and Isotopes
- Biomarkers in Disease Mechanisms
- Phytochemical Studies and Bioactivities
- Toxic Organic Pollutants Impact
- Metal-Organic Frameworks: Synthesis and Applications
- Histone Deacetylase Inhibitors Research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cancer Research and Treatment
- Genetics, Aging, and Longevity in Model Organisms
Chinese People's Liberation Army
2025
Ningxia University
2024
Hohai University
2023
Nantong University
2021-2022
Jilin Medical University
2011-2020
Health Commission of Jilin Province
2018-2020
Pharmaceutical Biotechnology (Czechia)
2009
Schematic illustration of (a) the preparation DHA@ZIF-8 NPs and (b) their application for cancer therapy.
Abstract Objective We aimed to find out the underlying mechanism of forskolin (Fsk) and 3‐isobutyl‐1‐methylxanthine (IBMX) on glioma stem cells (GSCs). Methods The expression cAMP‐related protein CREB pCREB as well apoptosis‐related proteins were detected through Western blot analysis. level proliferation growth rate human GSCs was measured thiazolyl blue tetrazolium bromide assay forming sphere assay. gene reverse transcription‐polymerase chain reaction. Results cAMP signaling pathway...
Antler velvet polypeptide (VAP) is a prominent bioactive component of antler velvet. Whereas uncharacterized crude extracts have typically been used in pharmacological studies, this study, the was isolated and purified by acid water extraction, ethanol precipitation, ammonium sulfate fractionation chromatography, progressively. Human umbilical vein endothelial cells (HUVECs) were induced with H2O2 followed treatment. Cell viability evaluated MTT assay. The apoptosis detected fluorescence...
Transient receptor potential ankyrin 1 (TRPA1), the non-selective cation channel, was found that can mediate generation of multiple sclerosis, while mechanism is still controversial. Lysophosphatidylcholine (LPC) a critical trigger sclerosis which results from syndrome neuronal inflammation and demyelination. In this work, we suggested TRPA1 LPC-induced oxidative stress cytotoxicity in OLN-93 oligodendrocyte. The expression detected by using quantitative real-time PCR (qRT-PCR)...
Cancer cell promotion of glycolysis provides a promising therapeutic target for cancer treatment. Dihydroartemisinin (DHA) displays cytotoxicity to multiple human tumor cells. However, its effects on pancreatic cells are not well studied. The objective this study was investigate the effect DHA glucose metabolism and viability in JF-305 To achieve these goals, measured with MTT assay, occurrence apoptosis detected. Glucose uptake, lactate production, ATP content were measured. Western...
Purpose of this article is to investigate high power microwave radiation damage rats. After 200mW/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> radiation, NO and GSH-pox serum in fourteen days group has obvious difference one day group, seven control (P<;0.05); SOD significant NOS significantly exceeds (P<;0.05). cAMP, β-EP HSP70 exceed ACTH Microwave may change organism overoxidation environment, restoration by changing cytokine...
Water-lubricated bearings have the advantages of pollution-free, simple structure, corrosion resistant, impact resistant. Therefore, they are widely used in underwater robots. Due to low-viscosity and low-speed water-lubricated bearings, their load-carrying capacity is naturally weak. Meanwhile, gravity propeller other factors often cause centerline journal be no longer parallel bearing hole. Thus, misaligned vertical plane, which further decreases bearing. In order improve CFD method...
This paper researched effect of passive smoking on growth rats. 30 male wistar rats were randomly devided control group(CG), low dose group (LDG)and high group(HDG), LDG and HDG breathed in smoke three six cigarettes respectively, twice every day, one time was hour, altogether 35 days. Body weight significantly lower than CG (P <; 0.05). NO MDA had significant difference to serum lung homogenate(P 0.05), GSH-pox obviously NOS SOD decreased homogenate Passive may lead growing decreased,...