A5100324163- Pancreatic and Hepatic Oncology Research
- Retinal Diseases and Treatments
- Gastric Cancer Management and Outcomes
- Peptidase Inhibition and Analysis
- Pancreatitis Pathology and Treatment
- Elbow and Forearm Trauma Treatment
- Orthodontics and Dentofacial Orthopedics
- Facial Rejuvenation and Surgery Techniques
- Oral microbiology and periodontitis research
- Orthopedic Surgery and Rehabilitation
- Parkinson's Disease Mechanisms and Treatments
- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Vitamin C and Antioxidants Research
- Cardiac electrophysiology and arrhythmias
- Nuclear Receptors and Signaling
- Protease and Inhibitor Mechanisms
- Facial Nerve Paralysis Treatment and Research
- Nerve injury and regeneration
- Dental Radiography and Imaging
- Immune cells in cancer
- Inflammation biomarkers and pathways
- Inflammatory Biomarkers in Disease Prognosis
- Kawasaki Disease and Coronary Complications
- Esophageal and GI Pathology
Xi'an Jiaotong University
2019-2025
Central Hospital of Putuo District
2023-2025
Nanchang University
2024-2025
Tianjin Medical University Cancer Institute and Hospital
2025
Beijing Luhe Hospital Affiliated to Capital Medical University
2022-2024
Wenzhou Medical University
2011-2024
Ruian People's Hospital
2012-2024
Affiliated Hospital of Southwest Medical University
2022-2024
Shandong University of Traditional Chinese Medicine
2024
State Administration of Traditional Chinese Medicine of the People's Republic of China
2024
Acute pancreatitis (AP) is a common digestive disease without specific treatment, and its pathogenesis features multiple deleterious amplification loops dependent on translation, triggered by cytosolic Ca
Background: Cancer-associated fibroblasts (CAFs) promote tumor progression through extracellular matrix (ECM) remodeling and extensive communication with other cells in microenvironment. However, most CAF-targeting strategies failed clinical trials due to the heterogeneity of CAFs. Hence, we aimed identify cluster tumor-promoting CAFs, elucidate their function determine specific membrane markers ensure precise targeting. Methods: We integrated multiple single-cell RNA sequencing (scRNA-seq)...
To investigate the potential role of lactate in relationship between periodontitis and biological aging. Cross-sectional data from 9,652 participants National Health Nutrition Examination Survey 2009-2014 were analyzed. Periodontitis was categorized based on Centers for Disease Control Prevention American Academy Periodontology (CDC/AAP) classification. Biological aging assessed KDM-BA acceleration PhenoAge acceleration, while levels using dehydrogenase (LDH). Weighted multivariable linear...
Abstract Background Pancreatic cancer (PC) is a highly aggressive tumor with poor prognosis that lacks specific diagnostic markers. Mucin 5AC (MUC5AC) member of the mucin family, heterogeneous group high molecular weight, heavily glycosylated proteins could be either membrane-bound or secreted. This multi-central study to evaluate performance serum MUC5AC in combination carbohydrate antigen 19-9 (CA19-9) for diagnosis PC Asian. Methods Sixty-one patients (comprised early pancreatic [ n = 30]...
The low survival rate or dysfunction of extracellular matrix (ECM)-based engineered organs caused by the adverse effects unfavourable local microenvironments on seed cell viability and stemness, especially excessive reactive oxygen species (ROS), prompted us to examine importance controlling oxidative damage for tissue transplantation regeneration. We sought improve tolerance cells transplant microenvironment via antioxidant pathways, thus promoting efficiency achieving better improved...
(1) Background: Asians tend to have a regressive midface. Midface augmentation is an effective treatment, and various materials been used as fillers for this purpose. Bio-Oss bone powder has strong positive effect on promoting new regeneration, in the dental field over 30 years. However, it not reported filler midface augmentation. (2) Objective: To evaluate safety efficacy of using treating retrusion resulting nasolabial folds, develop predictive model patient satisfaction. (3) Methods: 85...
The effect of different coffee and tea consumption on postprandial glucose lipid metabolism has never been reported previously. aim the present study was to investigate or at breakfast cardiometabolic risk factors in healthy individuals.
In order to find the risk factors of postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) according latest definition and grading system International Study Group Pancreatic Surgery (ISGPS) (version 2016) propose a nomogram for predicting POPF.We conducted retrospective analysis 232 successive cases PD performed at our hospital by same operator from August 2012 June 2020. POPF was diagnosed in accordance with ISGPS. The were analyzed univariate multivariate logistic...
Background Diabetic retinopathy (DR) is a common complication of diabetic patients. Retinal physiological function affected by hydration status. We aimed to explore the association between status and DR. Methods National Health Nutrition Examination Survey (NHANES) 2005-2008 was used perform this cross-sectional study. Serum osmolality assess for all participants calculated evaluated only older people. DR its severity were graded into mild non-proliferative retinopathy, moderate/severe...
Abstract Objective To investigate neuroinflammation under different periodontal status. Materials and Methods Experimental periodontitis was induced by molar ligation (Lig group) or injection of lipopolysaccharide (LPS, Lps group). Periodontal status assessed alveolar bone resorption inflammation. Micro‐computed tomography haematoxylin–eosin staining were performed to assess inflammation, respectively. Neuroinflammation glial cell proliferation proinflammatory factor expression. Microgliosis...
Objective: This study aimed to establish a model distinguish Kawasaki disease (KD) from other fever illness using the prognostic nutritional index (PNI) and immunological factors. Method: We enrolled total of 692 patients (including 198 with KD 494 children febrile diseases). Of those, 415 were selected be training group 277 validation group. Laboratory data, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), (PNI), factors, retrospectively collected for an...
Abstract Background The effectiveness of anterior crossbite treatment in preschool-aged children depends on the design and patient compliance. Common early appliances with steel wires acrylic resin can bring about numerous problems, such as toothache, sore gums mucous membrane injury. aim this study was to propose a new clear removable appliance provide preschool-age an improved experience occlusal interference treatment. Methods Appliances were designed help 3-dimensional (3D) digital...
Oligoasthenozoospermia is becoming a serious problem, but effective prevention or treatment lacking. Hyperoside, one of the main active ingredients in traditional Chinese medicine, may be oligoasthenozoospermia. In this study, we used cyclophosphamide (CTX: 50 mg/kg) to establish mouse model investigate therapeutic effect hyperoside (30 on CTX-induced All mice were divided into four groups: blank control group (Control), (Hyp), disease (CTX) and (CTX + H). Mice body weight, testicular sperm...
This cross-sectional study assessed the association of eating behavior, nutritional risk, and frailty with sarcopenia in 208 community-dwelling individuals aged ≥65 years who were recruited from random rural community care centers Chiayi County, Taiwan. The participants’ behavior was categorized into six categories. gait speed (GS), grip strength, appendicular skeletal muscle mass (ASM) based on these three parameters, which revealed that 50.9% participants had sarcopenia. In an adjusted...