A5065384840- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Respiratory viral infections research
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Malaria Research and Control
- Complement system in diseases
- Bacillus and Francisella bacterial research
- COVID-19 epidemiological studies
- Viral Infections and Outbreaks Research
- Zoonotic diseases and public health
- Influenza Virus Research Studies
- SARS-CoV-2 detection and testing
Bernhard Nocht Institute for Tropical Medicine
2017-2024
Robert Koch Institute
2022-2023
German Center for Infection Research
2019-2020
SARS-CoV-2 serosurveillance is important to adapt infection control measures and estimate the degree of underreporting. Blood donor samples can be used as a proxy for healthy adult population. In repeated cross-sectional study from April 2020 2021, September April/May 2022, 13 blood establishments collected 134,510 anonymised specimens donors in 28 regions across Germany. These were tested antibodies against spike protein nucleocapsid, including neutralising capacity. Seroprevalence was...
Abstract Background Malaria presents with unspecific clinical symptoms that frequently overlap other infectious diseases and is also a risk factor for coinfections, such as non-Typhi Salmonella. rapid diagnostic tests are sensitive but unable to distinguish between an acute infection requiring treatment asymptomatic malaria concomitant infection. We set out test whether cytokine profiles could predict disease status allow the differentiation bacterial bloodstream Methods created...
Influenza surveillance data from Africa indicate a substantial disease burden with high mortality. However, local influenza district hospitals limited laboratory facilities are still scarce.To identify the frequency and seasonal distribution of among hospitalized febrile children in rural hospital Ghana to describe differential diagnoses other severe infections.Between January 2014 April 2015, all temperature ≥38°C admitted were screened for A B by RT-PCR differentiated subtypes A(H1N1)pdm09...
Abstract A better understanding of disease-specific biomarker profiles during acute infections could guide the development innovative diagnostic methods to differentiate between malaria and alternative causes fever. We investigated autoantibody (AAb) in febrile children (≤ 5 years) admitted a hospital rural Ghana. Serum samples from 30 with bacterial bloodstream infection 35 Plasmodium falciparum were analyzed using protein microarrays (Protoplex Immune Response Assay, ThermoFisher)....
The German Biosecurity Programme was launched in 2013 with the aim to support partner countries overcome biological threats including natural outbreaks or intentional misuse of highly pathogenic agents. As part this programme, paper describes development and implementation a multilateral biosafety biosecurity training initiative, called 'Global Partnership Initiated Academia for Controlling Health Threats' (GIBACHT). To achieve its objectives, GIBACHT implemented blended-learning approach...