A5103286746- Retinal Imaging and Analysis
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Organ Transplantation Techniques and Outcomes
- Asthma and respiratory diseases
- Polysaccharides Composition and Applications
- Viral gastroenteritis research and epidemiology
- Anesthesia and Pain Management
- Acupuncture Treatment Research Studies
- Microbial Metabolites in Food Biotechnology
- Liver Disease Diagnosis and Treatment
- Mobile Health and mHealth Applications
- Intensive Care Unit Cognitive Disorders
- Optical Coherence Tomography Applications
- Influenza Virus Research Studies
- Pregnancy and preeclampsia studies
- Adipose Tissue and Metabolism
- Anesthesia and Sedative Agents
- Telemedicine and Telehealth Implementation
- Hepatitis Viruses Studies and Epidemiology
- Liver Disease and Transplantation
- Anesthesia and Neurotoxicity Research
- Hand Gesture Recognition Systems
- Bladder and Urothelial Cancer Treatments
Capital Medical University
2019-2024
Beijing Tian Tan Hospital
2024
Nanjing Normal University Taizhou College
2023
Shanghai University of Sport
2023
Nanjing Normal University
2023
West China Hospital of Sichuan University
2021-2022
West China Medical Center of Sichuan University
2022
Sichuan University
2014-2022
First Affiliated Hospital of Dalian Medical University
2022
Dalian Medical University
2022
Olfactory receptors (ORs) are expressed not only in the sensory neurons of olfactory epithelium, where they detect volatile substances, but also various other tissues their potential functions largely unknown. Here, we report physiological characterization human OR51E2, named prostate-specific G-protein-coupled receptor (PSGR) due to its reported up-regulation prostate cancer. We identified androstenone derivatives as ligands for recombinant receptor. PSGR can be activated with odorant...
Aim. We aimed to investigate and evaluate the preventive activity of puerarin on ovalbumin-induced asthma rat model. Materials Methods. Male Wistar rats were sensitized intraperitoneally days 0, 7, 14 challenged ovalbumin intratracheally day 21. Groups treated randomly either with placebo, puerarin, dexamethasone, or combined from 15 20. Inflammatory markers, including cell counts in bronchoalveolar lavage fluid (BALF), inflammatory cytokines, histopathology, coagulation parameters, such as...
Background: Previous observational studies have suggested the involvement of 25-hydroxyvitamin D [25(OH)D] in chronic pain. However, whether 25(OH)D is a novel target for management, causality remains unclear. Methods: A two-sample Mendelian randomization (MR) study was conducted to identify causal association between and low back pain (LBP). The primary analysis revealing from serum level (n = 417,580) on LBP (21,140 cases 227,388 controls). replicated performing MR estimates circulating...
Artificial intelligence (AI) has gained significant attention in healthcare consultation due to its potential improve clinical workflow and enhance medical communication. However, owing the complex nature of information, large language models (LLM) trained with general world knowledge might not possess capability tackle medical-related tasks at an expert level. Here, we introduce EyeGPT, a specialized LLM designed specifically for ophthalmology, using three optimization strategies including...
The streptozotocin (STZ) model is widely used in diabetes research. However, the cellular and molecular states of pancreatic endocrine cells this remain unclear. This study explored characteristics islet treated with STZ re-evaluated β-cell dysfunction regeneration model. We performed single-cell RNA sequencing from STZ-treated mice. High-quality data 2,999 were to identify clusters via Louvain clustering analysis. Principal component analysis (PCA), t-distributed stochastic neighbor...
Abstract Hepatic ischemia–reperfusion (IR) injury is a critical issue during liver transplantation (LT). Recent studies have demonstrated that IL-17a contributes to IR and steatohepatitis. However, the underlying mechanism not understood. This study aimed examine role of on hepatic in fatty investigate mechanisms. The correlation between serum levels function was analyzed LT patients receiving (n = 42) normal grafts 44). Rat model applied validate clinical findings. knockout (KO) wild-type...
To explore the expression of aquaporin 1 (AQP1) in bladder uroepithelium cell carcinoma (BUCC) and its relevance to recurrence.Tissue samples from 45 BUCC patients who underwent total cystectomy or transurethral resection tumor (TURBT) 40 with non-bladder cancers special detection treatments were collected. The level AQP1 tissues normal was assessed by immunohistochemistry so as analyze pathological patterns time recurrence patients.The levels 2.175±0.693 3.689±0.701, respectively,...
Physiotherapists are increasingly using video conferencing tools for their teleconsultations. Yet, the assessment of subtle differences in body movements remains a challenge. To support lower limb consultations, we present SoPhy, wearable technology consisting pair socks with embedded sensors patients to wear; and web interface that displays information about range weight distribution, foot movement, orientation physiotherapists real-time. We conducted laboratory study 40 which postgraduate...
To localize, quantify and compare angiogenic factors, vascular endothelial growth factor (VEGF), placental (PlGF), as well their receptors fms-like tyrosine kinase receptor (Flt-1) insert domain (KDR) in the placentas of normal pregnancy complications preeclampsia (PE), intrauterine fetal restriction (IUGR) PE + IUGR.In a prospective cross-sectional case-control study, 30 pregnant women between 24-40 weeks gestation, were recruited into four clinical groups. Representative samples stained...
Abstract Background The relationship between the type of anesthesia and survival outcomes gastric cancer patients is uncertain. This study compared overall outcome after surgery with total intravenous (TIVA) or inhalation (IHA). Methods Clinicopathological variables were retrieved from database Surgical Gastric Cancer Patient Registry in West China Hospital, Sichuan University. Patients grouped according to whether they received TIVA IHA during operation. Propensity score (PS) matching was...
Purpose: The study aims to explore the relationship and potential mechanisms between screen time anxiety have a clear understanding of role negative emotions emotion regulation, thus providing guidance for Chinese college students improve mental health. Methods: We conducted questionnaire survey by selecting 1721 academic from 6 colleges universities in 5 provinces China, data were analyzed through Process program SPSS mediating effect moderating effect. Results: There is significant...
Aim: Bladder cancer (BC) is one of the most common malignancies with poor prognosis. We aimed to identify a genetic signature for predicting prognosis BC. Materials & methods: Kaplan–Meier survival and Cox regression analyses were used construct prognostic using data from The Cancer Genome Atlas. Results: Fifty four upregulated 47 downregulated immune-related genes (IRGs) identified in A based on expression five IRGs was determined, which moderately accurate tumors. correlated tumor stage,...
<p style='text-indent:20px;'>In this paper we study a nonlocal diffusion model with double free boundaries in time periodic environment, which is the natural extension of boundary [<xref ref-type="bibr" rid="b17">17</xref>], where local used to describe population dispersal. We give existence and uniqueness global solution consider properties principle eigenvalue time-periodic parabolic-type problem. With help attractivity solutions, establish spreading-vanishing dichotomy. The sharp...
Background: Fospropofol disodium for injection (Fospropofol FD ) is a prodrug that metabolized into propofol to produce general anesthesia effect when administered intravenously. Objective: This study aimed assess the efficacy and safety of in comparison with medium/long-chain fat emulsion injections (propofol-MCT/LCT) induction adult patients undergoing elective surgeries. Setting: Nine academic medical centers China. Method: multicenter, randomized, double-blind, double-simulated,...
FATP1 plays an important role in the regulation of fatty acid metabolism and lipid accumulation. In this study, we investigated patterns expression various tissues obtained from calf adult Qinchuan cattle, differentiating adipocytes. Next, effect on preadipocyte differentiation cattle using overexpression interference assays. We also identified differentially expressed genes (DEGs) pathways associated with overexpression/interference. Our results reveal that was broadly heart, kidney,...