Zhengli Wu

ORCID: 0000-0002-9932-5395
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Research Areas
  • Aquaculture disease management and microbiota
  • Aquaculture Nutrition and Growth
  • Marine Bivalve and Aquaculture Studies
  • Mast cells and histamine
  • Environmental Toxicology and Ecotoxicology
  • Parasitic Infections and Diagnostics
  • Diet and metabolism studies
  • Gut microbiota and health
  • Aquatic Invertebrate Ecology and Behavior
  • Invertebrate Immune Response Mechanisms
  • Reproductive biology and impacts on aquatic species
  • Parasite Biology and Host Interactions
  • Insect and Pesticide Research
  • Insect Resistance and Genetics
  • Pharmacological Effects of Natural Compounds
  • Signaling Pathways in Disease
  • Dietary Effects on Health
  • Circadian rhythm and melatonin
  • Venomous Animal Envenomation and Studies
  • Bacterial Identification and Susceptibility Testing
  • Microbial Metabolism and Applications
  • Vibrio bacteria research studies
  • Fish Ecology and Management Studies
  • Asthma and respiratory diseases
  • Liver Disease Diagnosis and Treatment

Hunan Cancer Hospital
2025

Central South University
2009-2025

Southwest University
2009-2024

Soochow University
2022-2024

University of Manchester
2024

Panyu District Central Hospital
2024

Chinese Academy of Sciences
2024

Ningbo Institute of Industrial Technology
2024

University of Nottingham Ningbo China
2024

Ludong University
2024

We report a draft sequence for the genome of domesticated silkworm (Bombyx mori), covering 90.9% all known genes. Our estimated gene count is 18,510, which exceeds 13,379 genes reported Drosophila melanogaster. Comparative analyses to fruitfly, mosquito, spider, and butterfly reveal both similarities differences in content.

10.1126/science.1102210 article EN Science 2004-12-10

Microsporidian Nosema bombycis has received much attention because the pébrine disease of domesticated silkworms results in great economic losses silkworm industry. So far, no effective treatment could be found for pébrine. Compared to other known parasites, N. can unusually parasitize a broad range hosts. To gain some insights into underlying genetic mechanism pathological ability and host expansion this parasite, comparative genomic approach is conducted. The genome two antheraeae (an...

10.1186/1471-2164-14-186 article EN cc-by BMC Genomics 2013-03-16

C57BL/6 mice were fed with control diet, sugary-diet, or sugary-diet APE gavage for 8 weeks. After behavioral testing, the samples of serum, hippocampus, colon, and colonic contents collected further determination.

10.1039/d3fo04606k article EN Food & Function 2024-01-01

Abstract Microsporidia are fungal‐like unicellular eukaryotes which develop as obligate intracellular parasites. They differentiate into resistant spores that protected by a thick spore wall composed of glycoprotein‐rich outer layer or exospore and chitin‐rich inner endospore. In this study performed on the silkworm pathogen Nosema bombycis , we analyzed proteins (SWPs) proteomic‐based approaches, MALDI‐TOF MS LC‐MS/MS, 14 hypothetical (HSWPs) peptides were obtained in total. Furthermore,...

10.1002/pmic.200700584 article EN PROTEOMICS 2008-06-01

Laccase, a member of group proteins collectively known as multicopper oxidases, is hypothesized to play an important role in insect cuticle sclerotization by oxidizing catechols the their corresponding quinones, which then catalyze protein cross-linking reactions. Laccase 2 has been proved gene required for beetle tanning through RNA interference (RNAi) experiments on red flour Tribolium castaneum. The pine sawyer beetle, Monochamus alternatus (Coleoptero: Cerambycidae) serving major vector...

10.1111/j.1365-2583.2008.00803.x article EN Insect Molecular Biology 2008-05-09

Abstract Bifidobacteria can maintain the ecological balance of intestinal microorganisms and are closely linked to onset progression acute enteritis. Present research aimed investigate alleviation DSS-induced enteritis by bifidobacteria. In vivo colonoscopy was performed in mice observe colorectal mucosa pathological damage colon tissue colonic expression tight junction proteins (Occludin, Claudin-1, ZO-1) inflammatory factors (TNF-α, IL-1b, IL-6). The samples were collected for bacterial...

10.1556/066.2024.00186 article EN cc-by-nc Acta Alimentaria 2025-01-30

The homeostasis of circadian clock linked to bile acid (BA) metabolism and gut microbiota has profound benefits in maintaining the health status host. aim this study was investigate prevention regulation apple polyphenol extract (APE) on BA by means modulation rhythms mice. Eighty male C57BL/6 mice were randomized into four groups: 24-hour ad libitum standard chow group (AC), HFD (AF), restricted 12 h daytime feeding (DF), with APE treatment (DP). Five weeks later, sacrificed at 6 intervals...

10.1039/d1fo04116a article EN Food & Function 2022-01-01

ABSTRACT. Microsporidia are eukaryotic, obligate intracellular, spore‐forming parasites. The resistant spores, which harbor a rigid cell wall, critical for their host‐to‐host transmission and persistence in the environment. spore wall comprises two major layers: exospore endospore. In Nosema bombycis , proteins have been characterized—an endosporal protein, SWP30, an exosporal SWP32. Here, we report identification of third protein N. SWP25, gene has no known homologue. SWP25 is predicted to...

10.1111/j.1550-7408.2008.00375.x article EN Journal of Eukaryotic Microbiology 2009-03-01

The proper lipid content in the diets is crucial for fish growth and health. However, appropriate requirement of Amur sturgeon has not been systematically studied. This study was aimed to explore effects dietary levels on performance, metabolism, antioxidant immune status juvenile (Acipenser schrenckii). Six isonitrogenous containing 5.11% (L5), 8.87% (L9), 12.96% (L13), 16.93% (L17), 20.84% (L21) 24.88% (L25) were fed (4.16 ± 0.07 g) 10 weeks. L21 group had highest growth, feed utilization...

10.1016/j.aqrep.2023.101796 article EN cc-by-nc-nd Aquaculture Reports 2023-10-31

As micro-particle aggregates, bioflocs may be potential baits for ingestion by triangle sail mussels and supplementary feeding raises more concerns. Besides, a plasmid carrying the green fluorescent protein (GFP) gene was transformed into floc-forming Bacillus subtilis (GFP-B. subtilis) to visualize its colonization during ingestion. To investigate benefits of on H. cumingii, Chlorella vulgaris diets were supplemented with nothing (control group, CG) or accounting microalgae biomass at 25%...

10.1016/j.aqrep.2023.101904 article EN cc-by-nc-nd Aquaculture Reports 2024-01-12

To determine migration-related differences in serum lipid levels and to estimate the contribution of environmental factors these differences, authors conducted a cross-sectional study among 1, 222 residents southwestern China 1988 1989: 521 Yi farmers living remote rural area, 340 migrants an urban setting, 361 Han people same setting. Serum total high density lipoprotein cholesterol triglyceride were measured after 14-hour fast. Information on age, cigarette smoking, alcohol consumption,...

10.1093/oxfordjournals.aje.a009018 article EN American Journal of Epidemiology 1996-11-01

Respiratory tract infection with Pseudomonas aeruginosa is a common cause of hospitalization in immune-compromised individuals. However, the molecular mechanisms involved immune response to P. lung remain incompletely defined. In this study, we demonstrate that regulator calcineurin 1 (RCAN1) central negative inflammation mouse model acute bacterial pneumonia using opportunistic pathogen aeruginosa. RCAN1-deficient mice display greatly increased mortality following despite enhanced...

10.4049/jimmunol.1203196 article EN The Journal of Immunology 2013-04-16

Our previous study confirmed that the ameliorated effects of an intervention with apple polyphenol extract (APE) on hepatic steatosis induced by a high-fat diet (HFD) are dependent SIRT1. Since SIRT1 expression decreases age, it remains unclear whether APE is effective against in aged mice. Thus, 12-month-old C57BL/6 male mice were fed HFD to establish aging model and treated 500 mg/(kg·bw·d) for 12 weeks. Young (two months old) baseline used as controls examine natural steatosis. Compared...

10.1021/acs.jafc.3c00596 article EN Journal of Agricultural and Food Chemistry 2023-12-06
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