A5049265481- Maternal Mental Health During Pregnancy and Postpartum
- Cancer survivorship and care
- Economic and Financial Impacts of Cancer
- Child and Adolescent Psychosocial and Emotional Development
- Pregnancy and preeclampsia studies
- Cancer-related cognitive impairment studies
- Breastfeeding Practices and Influences
- Cancer Cells and Metastasis
- Gestational Diabetes Research and Management
- Cancer Treatment and Pharmacology
- Attachment and Relationship Dynamics
- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Breast Cancer Treatment Studies
- Ovarian cancer diagnosis and treatment
- Cancer Risks and Factors
- Cancer-related molecular mechanisms research
- Cardiovascular Issues in Pregnancy
- Pregnancy and Medication Impact
- Health and Medical Studies
- Cancer Genomics and Diagnostics
- Family Support in Illness
- Advanced Breast Cancer Therapies
- Colorectal Cancer Treatments and Studies
- Chronic Kidney Disease and Diabetes
Heidelberg University
2019-2024
University Hospital Heidelberg
2019-2024
Chirurgische Universitätsklinik Heidelberg
2024
Frauenklinik Heidelberg
2019-2022
Universitäts Frauenklinik
2020-2022
Heidelberg University
2022
Prevalence rates of peripartum depression and anxiety are high correlate with adverse maternal neonatal outcomes. Mindfulness-based interventions (MBI) have been shown to reduce mental distress during pregnancy. A multicenter, randomized controlled study was conducted after screening for depressive symptoms. The intervention group (IG) given access an 8-week supervised eMBI between weeks 29 36 pregnancy followed up 5 months postpartum. Psychometric data were collected using the Edinburgh...
Background Pregnant women are increasingly using mobile apps to access health information during the antenatal period. Therefore, digital solutions can potentially be used as monitoring instruments pregnancy. However, a main factor of success is high user engagement. Objective The aim this study was analyze engagement and factors influencing compliance in longitudinal targeting pregnant app with self-tracking. Methods Digitally collected data concerning demographics, medical history,...
Abstract Purpose Preeclampsia occurs in up to 15% of pregnancies and constitutes a major risk factor for cardiovascular disease. This observational cohort study aimed examine the association between preeclamptic outcomes as well primary specialized care utilization after delivery. Methods Using statutory claims data we identified women with singleton live births 2010 2017. Main included occurrence either hypertension or disease one more pregnancies, number contacts general practitioner...
The extracellular circulating microRNA (miR)-200 regulates epithelial-mesenchymal transition and, thus, plays an essential role in the metastatic cascade and has shown itself to be a promising prognostic predictive biomarker breast cancer (MBC). Expression levels of plasma miR-200 family were analyzed relationship systemic treatment, tumor cells (CTC) count, progression-free survival (PFS), overall (OS). miR-200a, miR-200b, miR-200c, miR-141, miR-429, CTC status (CTC-positive ≥ 5 CTC/7.5 mL)...
Breast cancer may negatively affect later pregnancy and childbirth. We aimed to analyze the impact of previous breast on obstetric outcomes in postdiagnosis pregnancies.
Abstract Women with complications of pregnancy such as preeclampsia and preterm birth are at risk for adverse long-term outcomes, including an increased future chronic kidney disease (CKD) end-stage (ESKD). This observational cohort study aimed to examine the CKD after delivery in a large obstetric Germany, taking into account preexisting comorbidities, potential confounders, severity CKD. Statutory claims data AOK Baden-Wuerttemberg were used identify women singleton live births between...
Preeclampsia is associated with a substantially increased long-term risk for cardiovascular, cerebrovascular and renal disease. It remains unclear whether to which extent specialized medical postpartum care sought. We aimed assess current utilization of primary medication prescription behavior in women who experienced preeclampsia. This retrospective observational study based on statutory claims data included 193,205 258,344 singleton live births between 2010 2017 Southern Germany....
Background Postpartum depression (PPD) is a severe mental disorder that often results in poor maternal-infant attachment and negatively impacts infant development. Universal screening has recently been recommended to identify women at risk, but the optimal time during pregnancy not defined so far. Thus, web-based technologies with widespread use among of childbearing age create new opportunities detect pregnancies high risk for adverse health outcomes an early stage. Objective The aim this...
Abstract Background: In recent years, the treatment of breast cancer has taken path towards personalized medicine. Based on individual tumor biology, therapy tailored to particular subtype is increasingly being used. The aim find most suitable for disease. However, success depends a large extent patient's adherence treatment. This, in turn, how tolerated and team cares patient. Patient-centered care seeks identify address needs each patient best form that person. Objectives: order improve...
<sec> <title>BACKGROUND</title> Perinatal maternal mental health problems, such as depression and anxiety, are highly prevalent during pregnancy postpartum. A promising treatment option is the use of electronic mindfulness-based interventions (eMBI), which can be provided in a low-threshold cost-effective manner. However, research underscores fact that face-to-face coaching sessions more effective than solely digital methods. synergistic approach, combining eMBI with direct coaching, could...
Background/Objectives: With breast cancer (BC) survival improving due to optimized therapy, enhancing quality of life has become increasingly important. Both diagnosis and treatment, with their potential side effects, pose risks mental well-being. Our study aimed analyze the incidence risk factors for disorders in BC patients. Methods: This retrospective analysis used claims data from AOK Baden-Wuerttemberg, including 11,553 patients diagnosed via ICD code C50 between 2010 2020 31,944...
Objective: With continuous optimization of breast cancer (BC) therapy and consequent improvement in survival, an increasingly relevant aspect is the enhancement quality life. Both diagnosis itself therapy, with its potential side effects, pose a risk to mental well-being. However, prevalence disorders patients varies widely literature. The aim this study was analyze incidence BC compared general population.
Background: Breast cancer diagnosis and treatment may negatively affect later pregnancy childbirth. Therefore, we aimed to analyze the impact of previous breast on adverse obstetric outcomes in postdiagnosis pregnancies.
With breast cancer (BC) survival improving due to optimized therapy, enhancing quality of life has become increasingly important. Both diagnosis and treatment, with their potential side effects, pose risks mental well-being. Our study aimed analyze the incidence risk factors for disorders in BC patients.
Perinatal maternal mental health problems, such as depression and anxiety, are highly prevalent during pregnancy post partum. Electronic mindfulness-based interventions (eMBIs) a promising treatment option, which can be provided in low-threshold, cost-effective manner. However, research underscores the fact that face-to-face coaching sessions more effective than solely digital methods. A blended care approach (eMBI with direct coaching) could amplify therapeutic impact on weight gain...
Introduction: Significant progress has been made in the targeted therapy of metastatic breast cancer (mBC) recent years. In this context, new biomarkers enable personalized management and individualized monitoring. Therefore, systemic treatment is based increasingly on biological characteristics tumor disease. Given challenges obtaining fresh tissue through biopsies, significance liquid biopsies for assessing circulating cells (CTCs) or DNA (ctDNA) growing importance detection prognostic...
Brustkrebs ist bei Frauen die am häufigsten diagnostizierte Krebserkrankung – sie spielt weltweit eine führende Rolle im Bereich der onkologischen Mortalität und Morbidität. Im Laufe des Lebens erkrankt durchschnittlich 1 von 8 an [1]. Durch intensivierte Früherkennungsprogramme einerseits sich ständig weiter entwickelnde onkologische Therapien andererseits konnte Prognose Brustkrebspatientinnen verbessert werden. In den letzten Jahren wurde Therapie Allgemeinen Behandlung Besonderen immer...
<sec> <title>BACKGROUND</title> In recent years, the treatment of breast cancer has taken path towards personalized medicine. Based on individual tumor biology, therapy tailored to particular subtype is increasingly being used. The aim find most suitable for disease. However, success depends a large extent patient's adherence treatment. This, in turn, how tolerated and team cares patient. Patient-centered care seeks identify address needs each patient best form that person. </sec>...
Surgery is the backbone of early-stage ovarian cancer (OC) management. However, in practice, there disagreement about extent surgical staging and whether additional adjuvant treatment should be provided. As omitting relevant diagnostic or therapeutic procedures might lead to undertreatment, we aimed structurally investigate practice addition prognostic factors a multicentre series patients (pts) diagnosed with OC.Within this retrospective, study, medical records 379 pts who had undergone...
Abstract Background The proliferation marker Ki-67 is a major pathological feature for the description of state disease in breast cancer. It helps to define molecular subtype and stratify between therapy regimens early cancer assess response. Circulating tumor cells (CTCs) are negative prognostic biomarker progression free (PFS) overall survival (OS) patients with metastatic Therefore, CTC count often described as surrogate burden. Both, decrease considered evidence presented work analyzed...
Anxiety disorders and depression during pregnancy are highly prevalent. Hospitalized pregnant women with high maternal or fetal risk represent a particularly vulnerable population often excluded from research samples. Screening for mental health is not routinely offered this particular patient group. Electronic mindfulness-based interventions constitute an accessible, convenient, cost-effective resource but have yet been evaluated acceptance in inpatient settings. To date, little known about...
Chronic kidney disease (CKD) is common in aging men and women. In contrast to other European countries, Germany lacks CKD registries. The aim of this study was determine the incidence stages 2-5 women Germany. Furthermore, differences between sexes terms comorbidities, potentially inappropriate medications (PIM), healthcare utilization were examined.In retrospective observational study, claims data from members a statutory health insurance fund aged 18 years or older with incident 2011 2018...
Introduction Perinatal depression (PND) is a frequently observed mental disorder, showing prevalence of up to 20% and resulting in unfavorable maternal neonatal outcomes. Targeted screening for PND offers the potential identify treat undiagnosed cases help prevent its deleterious consequences. The aim present study was evaluate participants' personal attitudes acceptance routine program pregnancy care, any underlying factors, appraise general perspective on perinatal health problems. Methods...