Beom Seok Kwak

ORCID: 0000-0003-0180-5102
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Research Areas
  • Breast Cancer Treatment Studies
  • Breast Lesions and Carcinomas
  • Cancer Risks and Factors
  • Medical Imaging Techniques and Applications
  • Breast Implant and Reconstruction
  • Cancer and Skin Lesions
  • BRCA gene mutations in cancer
  • Thyroid Cancer Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Bone health and osteoporosis research
  • Angiogenesis and VEGF in Cancer
  • Venous Thromboembolism Diagnosis and Management
  • Estrogen and related hormone effects
  • Reconstructive Surgery and Microvascular Techniques
  • Salivary Gland Tumors Diagnosis and Treatment
  • Hernia repair and management
  • Intestinal and Peritoneal Adhesions
  • Appendicitis Diagnosis and Management
  • DNA Repair Mechanisms
  • Pelvic and Acetabular Injuries
  • Parasitic infections in humans and animals
  • Nonmelanoma Skin Cancer Studies
  • Thyroid and Parathyroid Surgery
  • Male Breast Health Studies
  • Body Contouring and Surgery

Dongguk University Ilsan Hospital
2012-2023

Dongguk University
2007-2018

Chung-Ang University Hospital
2013

Asan Medical Center
2004-2007

University of Ulsan
2004-2007

Ulsan College
2004-2007

Hanyang University Seoul Hospital
2006

Tamoxifen (Tam) has long been a top treatment option for breast cancer patients, but the challenge of eliminating recurrence remains. Here, we identify signalling pathway involving ELOVL2, ELOVL2-AS1, and miR-1233-3p, which contributes to drug resistance in Tam-resistant (TamR) cancer. noncoding RNA, was significantly upregulated by its antisense gene, is known be downregulated TamR cells. Additionally, ELOVL2-AS1 underwent most hypermethylation MCF-7/TamR Furthermore, patients with who...

10.1080/15592294.2023.2276384 article EN cc-by-nc Epigenetics 2023-10-31

The incidence of breast cancer in Korea has been increasing recent years, such that it is now the most common female cancer. Breast characterized by an earlier age onset than Western countries, suggesting would be related with genetic background. We assayed germline mutations BRCA genes to evaluate their pathology Korean patients. study subjects consisted 173 patients at clinically higher risk and 109 unselected Germline entire coding sequences BRCA1 BRCA2 were analyzed...

10.3346/jkms.2004.19.2.269 article EN Journal of Korean Medical Science 2004-01-01

With varied reports on the impact of time to appendectomy clinical outcomes, purpose this study was determine effect preoperative in-hospital delay outcome for patients with acute appendicitis.A retrospective review 1,076 who had undergone an between January 2010 and December 2013 conducted.The outcomes surgery pathologic findings were analyzed according elapsed time. The overall from onset symptoms positively associated advanced pathology, increased number complications, prolonged hospital...

10.3393/ac.2018.34.1.11 article EN cc-by-nc Annals of Coloproctology 2018-02-28

A primary fibrosarcoma of the breast is a rare tumor. Here we report on case that presented as palpable left mass in 47-year-old woman. The physical examination revealed 3 cm sized, round upper outer breast. mammograms partially circumscribed and obscured, high density quadrant An ultrasonogram demonstrated ovoid, hypoechoic with peripheral increased vascularity Doppler imaging. Surgical excision was performed pathology low grade fibrosarcoma.

10.4048/jbc.2011.14.2.156 article EN cc-by-nc Journal of Breast Cancer 2011-01-01

Backgrounds/Aims Major hepato-pancreato-biliary (HPB) surgery is usually performed via an open method rather than a laparoscopic method. Postoperative ileus (POI) classic complication after surgery. The purpose of this study was to determine whether polylactic film useful in the prevention POI. Methods A total 179 patients who underwent major HPB between 2005 and 2014, were retrospectively reviewed. diagnosis POI made by physical examination, laboratory, radiological findings. Surgi-Wrap®...

10.14701/ahbps.2016.20.4.191 article EN Annals of Hepato-Biliary-Pancreatic Surgery 2016-01-01

Cordyceps militaris has been widely used as a traditional medicine in East Asia. Its effects against breast cancer have reported previously. However, whether C. ‐induced cell death is immunogenic remains unelucidated. This study aimed to determine ethanolic extracts of (CM‐EE) could induce (ICD) immunotherapy improve the efficacy immune checkpoint inhibitors. Human and mouse cells were treated with various concentrations CM‐EE for 72 h, cytotoxicity was measured using sulforhodamine B assay....

10.1155/2020/9053274 article EN cc-by Evidence-based Complementary and Alternative Medicine 2020-01-01

Pulmonary Thromboembolism following Mastectomy with Immediate TRAM in the Patients Breast Cancer : a Prospective Study Jung Sun Lee, Byung Ho Son, Hye Sook Choi, Min Sung, Soo Hong, Kyung Kim, Hee Jeong Beom Seok Kwak, Sei Hyun Ahn, Tack Jong Jin Sup Eom Department of Surgery, Pulmonology, and Plastic University Ulsan, College Medicine Asan Medical Center, Seoul, Korea

10.4048/jbc.2006.9.4.354 article EN cc-by-nc Journal of Breast Cancer 2006-01-01

Do Yeun Kim, M.D., Yong-Seok Hee Jin Huh, Jong Sun Choi, Jeong Seok Yeo, Beom Kwak, and Lae Chae, M.D.. Korean J Lab Med 2011;31:18-21. https://doi.org/10.3343/kjlm.2011.31.1.18

10.3343/kjlm.2011.31.1.18 article EN cc-by-nc Annals of Laboratory Medicine 2011-01-01

10.3348/jksr.2013.68.5.423 article EN cc-by-nc Journal of the Korean Society of Radiology 2013-01-01

Totally extraperitoneal (TEP) hernia repair has gained in popularity the past two decades. Despite advantages TEP repair, approach is hindered by relatively long learning curve of surgery. We tried to estimate necessary number repetitions using logarithmic and exponential function models.

10.7602/jmis.2016.19.4.126 article EN cc-by-nc Daehan nae'si'gyeong bog'gang'gyeong oe'gwa haghoeji/Journal of minimally invasive surgery 2016-12-12

immediate reconstruction provides psychological satisfaction and good cosmetic outcome for patients with breast cancer. However, this is a lengthy procedure to perform, there increased risk of pulmonary thromboembolism (PTE). The purpose study was evaluate the efficiency use low molecular weight heparins (enoxaparin) prophylaxis against pulmomary followed by mastectomy an transverse rectus abdominis myocutaneous flap (TRAM) in Methods: A total 123 underwent skin-sparing TRAM....

10.4048/jbc.2008.11.3.125 article EN cc-by-nc Journal of Breast Cancer 2008-01-01

We report here on a case of 51-year-old woman with metastatic small cell carcinoma the breast that came from her cancer uterine cervix. She underwent radical hysterectomy bilateral salpingo-oophorectomy due to cervix, and adjuvant radiotherapy was administered pelvis. Breast metastasis palpable mass then occurred 3 months after primary surgery. Simple mastectomy chemotherapy were performed. initially showed good response therapy, yet she ultimately died multiple metastases fulminating...

10.1159/000486194 article EN cc-by-nc Case Reports in Oncology 2018-01-17

10.1007/s12639-018-1003-1 article EN Journal of Parasitic Diseases 2018-05-10

Pegfilgrastim is a widely used long-acting granulocyte colony-stimulating factor (G-CSF) that prevents febrile neutropenia (FN) in patients with breast cancer receiving chemotherapy. This study aimed to evaluate the incidence of chemotherapy-related FN events and other adverse (AEs) during chemotherapy Korean treated pegfilgrastim as secondary prophylactic support.This was multicenter, open-label, prospective, observational study. A total 1255 were enrolled from 43 institutions. The...

10.1016/j.breast.2023.103585 article EN The Breast 2023-10-02

Purpose: Axillary lymph node metastasis is one of the most important prognostic factors in breast cancer. Previous reports show differences that clinicopathologic influence systemic recurrence and survival axillary negative Thus, we have attempted to determine on Methods: We retrospectively reviewed data 1,351 cancer patients who underwent curative surgery such as age, sex, body mass index (BMI), family history, bilateral cancer, operation method, tumor size, stage, histologic grade, number...

10.4174/jkss.2009.77.4.238 article EN Journal of the Korean Surgical Society 2009-01-01

A 48-year-old man presented for evaluation of general weakness. Because he had a history excessive alcohol use, an abdominal computed tomography scan was obtained, which revealed left adrenal mass. Hormonal showed elevated levels urinary catecholamines. Bilateral hilar lymphadenopathy detected on chest radiograph. The suspected diagnosis asymptomatic pheochromocytoma with sarcoidosis. We performed mediastinoscopic lymph node biopsy, followed by endoscopic adrenalectomy. Histologic tissue...

10.1097/smj.0b013e3181a06613 article EN Southern Medical Journal 2009-05-01
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