A5042113273- Colorectal Cancer Treatments and Studies
- Gut microbiota and health
- Lung Cancer Treatments and Mutations
- Nutrition and Health in Aging
- Cardiovascular Health and Risk Factors
- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- Hepatitis C virus research
- Sarcoma Diagnosis and Treatment
- Sepsis Diagnosis and Treatment
- Retinal Diseases and Treatments
- Medical Imaging Techniques and Applications
- Gastric Cancer Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Surgical Treatments
- Ubiquitin and proteasome pathways
- Radiomics and Machine Learning in Medical Imaging
- Hepatitis B Virus Studies
- Stoma care and complications
- Micro and Nano Robotics
- SARS-CoV-2 detection and testing
- Ocular Oncology and Treatments
- Cardiac tumors and thrombi
- Anorectal Disease Treatments and Outcomes
- Heme Oxygenase-1 and Carbon Monoxide
University of Electronic Science and Technology of China
2025
First Hospital of Jilin University
2024
Jilin University
2024
University College London
2024
China-Japan Friendship Hospital
2024
Huazhong University of Science and Technology
2013-2022
Tongji Hospital
2014-2022
Sun Yat-sen University
2021
Union Hospital
2017-2020
State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing
2019
Emerging evidence suggests a potential relationship between gut microbiota and the host response to chemotherapeutic drugs including 5-fluorouracil (5-Fu). Fusobacterium nucleatum (Fn) has been linked initiation progression of colorectal cancer (CRC). Unfortunately, little was known about Fn infection efficacy. Here, we investigate efficacy 5-Fu in CRC.Differentially expressed genes CRC cell lines induced by were analyzed based on whole genome microarray analysis Then, explored upregulation...
During the outbreak of COVID-19, outdoor activities were limited and digital learning increased. Concerns have arisen regarding impact these environmental changes on development myopia.To investigate in myopia young Chinese schoolchildren during COVID-19.In this observational study, 2 groups students from 12 primary schools Guangzhou, China, prospectively enrolled monitored grade to 3. Comparisons between exposure nonexposure made evaluate any association COVID-19 period myopia. The group...
Myopia is a common cause of vision loss, and its prevalence increasing globally.To evaluate the effects school-based family health education via WeChat in raising parents' awareness myopia prevention behavior controlling development children.A single-masked cluster randomized clinical trial children was conducted from October 1, 2018, to December 31, 2020, among grade 1 students 12 primary schools Guangzhou, China. The were randomly selected 2 districts intervention control groups. All...
Overexpression of multidrug resistance proteins (Mdrs) and enhanced antiapoptotic capability are two the main mechanisms by which Bcr/Abl+ chronic myeloid leukemia cells acquire drug resistance; however, it has been shown that Mdr-1 expression provides minimal protection against cell apoptosis induced chemotherapeutic drugs. The mechanism an antiapoptosis capacity in drug-resistant process needs to be further understood. Here, we identified human brain expressed X-linked 1 (hBex1) as a...
Milk fat globule epidermal growth factor 8 (MFG-E8) is an opsonin involved in the phagocytosis of apoptotic cells. In patients with chronic obstructive pulmonary disease (COPD), cell clearance defective. However, whether aberrant MFG-E8 expression this defect unknown. study, we examined COPD patients. MFG-E8, interleukin (IL)-1β and transforming (TGF)-β levels were measured plasma 96 (93 males, 3 females; age range: 62.12±10.39) 87 age-matched healthy controls (85 2 64.81±10.11 years) using...
Background:The effect of adjuvant chemotherapy on stage II colon cancer remains constantly controversial.Recently, however, several studies have reported the definite survival benefit (ACT) in T4 disease (stage IIB and IIC) among patients.The following study investigates efficacy ACT patients with poorly differentiated IIA cancer.Methods: The first cohort eligible (N=38384) diagnosed was selected from Surveillance, Epidemiology, End Results database (SEER) between January 1, 2004, December...
Is circulating heme oxygenase-1 (HO-1) associated with the risk of polycystic ovary syndrome (PCOS)? Lower HO-1 is a higher PCOS in non-obese women, dose-related manner. one most common endocrine disorders women reproductive age, increasing worldwide incidence. plays crucial role many physiological systems, potent anti-inflammatory, antioxidant and antimetabolic properties. This hospital-based case–control study included 80 healthy control seen at Reproductive Center Tongji Hospital (Wuhan,...
Objective: This study was to investigate guiding role of elevated pretreatment serum carcinoembryonic antigen (CEA) levels for ACT receipt in stage IIA colon cancer. Methods: Eligible patients diagnosed with cancer (N = 21848) were identified from the Surveillance, Epidemiology, and End Results (SEER) database between January 2004 December 2010. Pearson's chi-squared tests, Cox proportional hazards regression models Kaplan–Meier methods performed. Propensity score matching (PSM) used...
Background: Yes-associated protein (YAP) is a downstream effecter of Hippo signaling pathway, and has been linked to the initiation development colorectal cancer (CRC).However, clinical significance YAP in CRC remains controversial.This study was designed investigate CRC.Methods: We selected 206 eligible patients diagnosed with from 2003 2007.Tissue microarray (TMA) blocks were made formalin-fixed paraffin-embedded tissues 158 corresponding normal colonic tissues.Using TMA blocks, we...
Fabrication of metal-oxide nanotubes with quasi-one dimensional (Q1D) nanostructure is complex and expensive.In this work, mesoporous Al-doped SnO 2 were fabricated by a facile route simple electrospinning.SEM HRTEM characterizations these exhibited distinctive hollow Q1D structure 150 nm inner diameter 250 outer diameter.The gas-sensing properties the varying Al/Sn ratio tested under variable temperature formaldehyde (HCHO) concentration.At first, response increased rise Al amount reached...
Abstract Choroid plexus tumors (CPT) are rare and highly vascularized neoplasms that have three histologically confirmed diagnoses, including choroid papilloma, atypical carcinoma (CPC). This study aimed to determine the epidemiology survival of patients with CPTs develop a nomogram quantify prognosis CPT. Data 808 who were diagnosed as CPT between 2000 2020 was obtained from surveillance, epidemiology, end results database. Descriptive analysis used assess distribution tumor-related...
<h3>Background:</h3> Systemic sclerosis (SSc) is an autoimmune disease characterised by the production of autoantibodies, which leads to fibrosis and finally damage various tissues organs. Recent studies have demonstrated activation aberrant persistence M2-like macrophages in tissues, implicating these cells as a source pro-fibrotic inflammatory mediators. However, interplay between autoantibodies remains largely unexplored. In this study, we aimed investigate role disease-specific...