- Orthopaedic implants and arthroplasty
- Hip disorders and treatments
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Bone and Joint Diseases
- Osteoarthritis Treatment and Mechanisms
- Lower Extremity Biomechanics and Pathologies
- Acute Myeloid Leukemia Research
- Hip and Femur Fractures
- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Gastrointestinal disorders and treatments
- Aortic Disease and Treatment Approaches
- Scoliosis diagnosis and treatment
- Cancer Genomics and Diagnostics
- Bone health and treatments
- Bone fractures and treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Pelvic and Acetabular Injuries
- Aortic aneurysm repair treatments
- Cardiac Arrest and Resuscitation
- Venous Thromboembolism Diagnosis and Management
- Lymphoma Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Bone Tissue Engineering Materials
Kyoto University
2016-2025
Kyoto University Hospital
2012-2024
Kyocera (United States)
2020-2022
Creative Commons
2020-2022
Osaka Red Cross Hospital
2020
Kubota (Japan)
2019
Kyoto City Hospital
2016-2018
Kumamoto University Hospital
2009-2014
Kumamoto City Hospital
2009-2014
Kumamoto University
2009-2011
Using a simple classification method, we aimed to estimate the collapse rate due osteonecrosis of femoral head (ONFH) in order develop treatment guidelines for joint-preserving surgeries.We retrospectively analyzed 505 hips from 310 patients (141 men, 169 women; mean age 45.5 years (sd 14.9; 15 86)) diagnosed with ONFH and classified them using Japanese Investigation Committee (JIC) classification. The JIC system includes four visualized types based on location size osteonecrotic lesions...
The formation of a biofilm on the implant surface is major cause intractable implant-associated infection. To investigate antibiotic concentration needed to eradicate bacteria inside biofilm, minimum eradication (MBEC) has been used, mostly against in vitro biofilms plastic surfaces. produce more clinically relevant environment, an MBEC assay stainless-steel implants formed rat femoral infection model was developed. rats were implanted with stainless steel screws contaminated by two...
Objective: To investigate the effects of high-velocity resistance training on muscle function, properties, and physical performance in patients with hip osteoarthritis by comparison those low-velocity training. Design: Single-blind randomized controlled trial. Setting: Home-based exercise programmes. Subjects: A total 46 women were randomly assigned to ( n = 23) or group. Interventions: Both groups underwent an eight-week daily home-based programme using elastic band. Exercises involved...
Osteonecrosis of the femoral head (ONFH) is a refractory disease requiring joint replacement in young patients. Regenerative therapies have been developed.
Aims This study was performed to investigate the association between acetabular morphology and joint space narrowing rate (JSNR) in non-arthritic hip. Methods We retrospectively reviewed standing whole-leg radiographs of patients who underwent knee arthroplasty from February 2012 March 2020 at our institute. Patients with a history hip surgery, Kellgren-Lawrence grade ≥ II osteoarthritis, or rheumatoid arthritis were excluded. The JSNR measured, normalized (nJSNR) calculated by calibrating...
High-dose trimethoprim-sulfamethoxazole (TMP-SMX) is known to cause hyperkalemia by blocking amiloride-sensitive sodium (Na) channels in distal nephrons. The purpose of this study was establish whether the standard dose TMP-SMX could electrolyte disorders.Serum Na, potassium (K) and creatinine (Cr) levels were examined retrospectively 53 77 patients prescribed TMP-SMX, before after taking antibiotic combination.Electrolyte disorders (Na < 135 mEq/l and/or K > 5.0 mEq/l) found 14 (26.4%)...
We evaluated the safety and clinical outcomes of a single local administration gelatin hydrogel impregnated with recombinant human fibroblast growth factor (rhFGF)-2 for treatment precollapse stage osteonecrosis femoral head (ONFH).Patients ONFH (precollapse ≤2) received 800 μg rhFGF-2-impregnated were followed up one year. The surgery was performed using minimally invasive technique involving 1-cm skin incision, walking allowed from day postoperatively. primary included occurrence adverse...
Hip-spine syndrome was originally described by Offierski and MacNab, who argued that the flexion deformity of hip rotated pelvis forward, causing spine symptoms. We additionally hypothesized in patients have osteoarthritis (OA) hip, is tilted anteriorly to compensate for anterior acetabular coverage defect. investigated factors associated with pelvic tilt (PT) had OA due dysplasia.We retrospectively reviewed medical records undergone total arthroplasty between January 2009 December 2017...
Fusion of a joint reportedly increases force in the adjacent joints and leads to progression arthritis. Whether lumbar spinal fusion hip promotes wear space is unclear. The purpose this study was evaluate rate joint-space narrowing following examine effects number levels fused on joint-narrowing rate.We retrospectively reviewed data for patients who underwent from 2011 2018 at our institute. Patients with previous surgery, Kellgren-Lawrence grade ≥II osteoarthritis, dysplasia, rheumatoid...
Purpose: To elucidate the relation between certain preoperative physical parameters and walking with a limp after total hip arthroplasty (THA) determine whether it is possible to predict ability of patients 6 months THA. Methods: The subjects this study comprised 74 female who had undergone unilateral Before surgery, abductor knee extensor strengths were measured, cross-sectional areas (CSAs) gluteus medius rectus abdominis muscles Timed Up Go test was conducted. then divided into two groups...
Purpose: The purpose of this study was to investigate the effects an exercise program focusing on hip external rotator muscle physical recovery in early post-operative period total arthroplasty (THA).Methods: Patients who underwent THA were randomized group (n = 14) or a control 14). In group, performed 5 times per week for four weeks. Outcome measures pain, range motion, strength lower extremity and Timed Up Go (TUG) test.Results: Both abductor (effect size 0.60) TUG test size= −0.53)...
Abstract Idiopathic osteonecrosis of the femoral head (IONFH) is an ischemic disorder that causes bone necrosis head, resulting in hip joint dysfunction. IONFH a polygenic disease and steroid alcohol have already known to increase its risk; however, mechanism remains be elucidated. We performed genome-wide association study using ~60,000 subjects found two novel loci on chromosome 20q12 12q24. Big data analyses identified LINC01370 as candidate susceptibility gene locus. Stratified analysis...
Abstract Background A larger daily cumulative hip loading, which is the product of external adduction moment (HAM) impulse during gait and number steps per day has been identified as a factor associated with progression secondary osteoarthritis (OA). The cause increased HAM in patients OA not identified. purpose this study was to identify parameters OA. Methods Fifty-five (age 22–65 years) mild-to-moderate participated cross-sectional study. measured using three-dimensional analysis system....