Purpose To explore the potential of texture analysis based on apparent diffusion coefficient (ADC) maps, as a predictor local invasion depth (stage pT1‐2 versus pT3‐4) and nodal status (pN0 pN1‐2) rectal cancer. Materials Methods Sixty‐eight patients with cancer underwent preoperative magnetic resonance (MR) imaging including weighted (DWI) at 3.0 Tesla system. Routine ADC variables (ADC mean , min max ), histogram features (skewness, kurtosis) gray level co‐occurrence matrix (entropy,...

Abstract Ferroptosis, an iron‐dependent form of regulated cell death driven by excessive accumulation lipid peroxides, has become a promising strategy in cancer treatment. Cancer cells exploit antioxidant proteins, including Ferroptosis Suppressor Protein 1 (FSP1), to prevent ferroptosis. In this study, it is found that the E3 ubiquitin ligase TRIM21 bound FSP1 and mediated its ubiquitination on K322 K366 residues via K63 linkage, which essential for membrane translocation ferroptosis...

Abstract Effective reinforcement measures for the surrounding rock of tunnel are crucial to ensure safety engineering. Fibers very effective in improving quality interface; however, promote application fiber mortar (FM) lining reinforcement, it is necessary study bonding performance between FM and rock. The mechanical properties ordinary (OM) were investigated, tests conducted. effect polypropylene (PP) fibers on influence PP surface with different roughness bond analyzed detail. A 3D...

Noninvasive and precise methods to estimate treatment response identify hepatocellular carcinoma (HCC) patients who could benefit from transarterial chemoembolization (TACE) are urgently required. The present study aimed investigate the ability of intratumoral peritumoral radiomics based on contrast-enhanced magnetic resonance imaging (CE-MRI) preoperatively predict tumor TACE in HCC patients.A total 138 with received were retrospectively included randomly divided into training validation...

Although the molecular changes that characterize gliomas have been studied, pathogenesis of tumor development remains unclear. p21 contributes to gliomagenesis by stabilizing cyclin D1-cdk4 kinase complexes, suggesting D1 and cdk4 may also be required for glial development. In this study, we used a mouse model attempt confirm hypothesis, finding played active roles in not only but microenvironment. Loss blocked development, loss did prevent from developing. Instead, impeded progression...

Background: To investigate whether CT findings can predict the invasiveness of persistent cancerous pure ground glass opacity (pGGO) by correlating imaging features pGGO with pathological changes. Materials and Methods: Ninety five patients pGGOs were included. Three radiologists evaluated morphologic these at high resolution (HRCT). Binary logistic regression was used to assess association between histopathological classification (pre-invasive invasive groups). Receiver operating...

Purpose To prospectively evaluate the accuracy of diffusion‐weighted (DW) magnetic resonance (MR) imaging with background signal suppression (MR‐DWIBS) for detecting mediastinal lymph node metastasis nonsmall‐cell lung cancer (NSCLC). Materials and Methods MR‐DWIBS was performed in 42 consecutive patients (27 men, 15 women; age range, 42–78 years; median age, 55 years) histologically proven NSCLC. The visualization rate metastatic (MLN) benign (BLN) enlarged nodes (ELN) normal‐sized (NLN)...

To explore the role of deep learning (DL) and radiomics-based integrated approach based on contrast enhanced magnetic resonance imaging (CEMRI) for predicting early recurrence (ER) in hepatocellular carcinoma (HCC) patients after curative resection.

To compare the treatment outcomes of concurrent involved-field radiotherapy and XELOX (oxaliplatin capecitabine) versus chemotherapy alone in gastric adenocarcinoma patients with locoregional recurrence.From 2004 to 2008, 79 recurrent cancer after curative resection tumor were enrolled. Among them, 41 received (median dose 50 Gy) by a 3-dimensional conformal technique chemotherapy, 38 treated 130 mg/m, capecitabine 1000 twice daily, 3 wk each cycle).The radiochemotherapy group showed better...

Background This study used magnetic resonance imaging (MRI) to monitor changes brain metastases and investigate the signs evaluate treatment efficacy determine prognosis following radiotherapy for from lung cancer. Methods A total of 60 non‐small cell cancer patients with oligometastases were selected. MRI scans conducted before 3, 6, 9, 12, 18, 24, 30 months after radiotherapy. The tumor peritumoral edema diameters, Cho/Cr values, elevation Lip peak value, whether island ( yu‐yuan ) sign or...

The aim of this study was to explore the efficacy and adverse reactions CT-guided radioactive 125I-seed implantation treatment combined with chemotherapy for platinum-resistant recurrent ovarian carcinoma.From September 2010 December 2012, 23 patients carcinoma were enrolled. All refused, could not bear, or suitable surgery. They all had no more than 3 lesions, which detected also be measured by CT. clarified as single-lesion multiple-lesion groups. A total 41 lesions underwent from 8 106...

Background: To map detail distribution of metastatic supraclavicular (SCV) lymph nodes (LN) in esophageal cancer (EC) patients and determine the precise radiation therapy clinical target volume (CTV). Methods: A total 101 thoracic carcinoma after surgery experienced SCV LN metastasis were retrospectively examined. The region is further divided into four subgroups. Using hand drawings registration, mapped to a template computed tomogram provide visual impression nodal frequencies anatomic...

// Yijun Luo 1,2 , Xiaoli Wang Yuhui Liu 3 Chengang 1 Yong Huang Jinming Yu 2 and Minghuan Li School of Medicine Life Sciences, University Jinan-Shandong Academy Medical Jinan, Shandong Province, China Department Radiation Oncology, Cancer Hospital Affiliated to University, Radiology, Correspondence to: Li, email: Keywords : esophageal carcinoma, radiotherapy, target volume definition, lower cervical lymph node, risk factors Received September 13, 2016 Accepted January 10, 2017 Published 19,...

to explore the clinical value of 3.0T magnetic resonance (MR) imaging compared with computer-aided MR diagnosis (MR-CAD) in differential benign and malignant breast tumors.MRI method MR-CAD was used a total 93 lesions 78 patients, based on morphological time-intensity-curve (TIC) analysis. The accuracy two modalities differentiating tumor compared.MR-CAD yielded statistically better than MRI method. For 51 mass-like lesions, had no difference diagnosing accuracy, but 42 non-mass-like...

Purpose To investigate the ability of potential imaging biomarkers based on 18 F-AlF-NOTA-PRGD2 positron emission tomography/computed tomography ( F-RGD PET/CT) and dynamic contrast-enhanced magnetic resonance (DCE-MRI) to predict response bevacizumab combined with conventional therapy in postoperative newly diagnosed glioblastoma. Methods Twenty patients glioblastoma after surgery were prospectively enrolled receive plus concurrent radiotherapy temozolomide (CCRT). PET/CT DCE-MRI performed...

The present study aimed to assess the expression and prognostic significance of remodeling spacing factor 1 (RSF1; HBXAP) in renal cell carcinoma (RCC). RSF1 was analyzed using immunohistochemistry on tissue samples from a consecutive series 137 patients with RCC who underwent tumor resection between November 2000 March 2004. associations expression, clinicopathological factors patient survival were investigated. Immunohistochemistry revealed that highly expressed 43.1% (59/137) samples....

Radiation is an important modality for cervical and upper-thoracic esophageal squamous cell carcinoma (ESCC). Delineating the lymph node clinical target volume (CTVn) EC remains a challenging task. The present paper retrospectively analyzes distribution of affected nodes upper thoracic ESCC on CT images to provide reference determination CTVn. cases untreated or patients with regional metastases at diagnosis were analyzed. scans done assess extent circumferential involvement local-regional...

Background: Accurate preoperative judgment of lymph node (LN) metastasis is a critical step in creating treatment strategy and evaluating prognosis rectal cancer (RC) patients. Objective: This study aimed to explore the value T1 mapping amide proton transfer weighted (APTw) imaging predicting LN patients with cancer. Methods: In retrospective study, twenty-three pathologically confirmed adenocarcinoma who underwent MRI surgery from August 2019 2021 were selected. Then, 3.0T/MR sequences...

Abstract Introduction Intravitreal injections of anti-vascular endothelial growth factor (anti-VEGF) drugs have been widely used in patients with macular edema (ME) secondary to retinal vein occlusion (RVO); however, recurrence is a major concern. This study aims observe the clinical effects atorvastatin and intravitreal therapy treatment branch or central RVO-ME coexistent carotid plaques (CP). Methods analysis A prospective randomized controlled trial will be conducted. Sixty-four...

Systemic immunity is essential for driving therapeutically induced antitumor immune responses, and the spleen may reflect alterations in systemic immunity. This study aimed to evaluate predictive value of contrast-enhanced CT-based radiomics progression-free survival (PFS) patients with locally advanced cervical cancer (LACC) who underwent definitive chemoradiotherapy (dCRT). Additionally, we investigated role features changes volume assessing retrospective included 257 LACC dCRT. The were...

Offshore wind power has the advantages of abundant resources, high cleanliness and ease consumption, its role in building a new system is becoming more prominent, driven by goal carbon compliance neutrality. The AC convergence offshore still main method, rapid fluctuations speed sudden increases load can cause frequency bus, reducing quality. This paper summarises side structure analyses factors affecting stability bus. Subsequently turbine participation regulation compared an strategy based...

The rate of pleural metastasis in peripheral lung cancer is high, and the dry easily missed diagnosis preoperatively cause unnecessary surgery. Therefore, preoperative particularly important. To review multislice spiral computed tomography (MSCT) image with dissemination, to discuss its diagnostic value for understanding dissemination.Reviewed analyzed MSCT images pathologically or clinically diagnosed dissemination 27 patients. Analyze imaging characteristics respectively from thickening...