A5038725800- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Pneumonia and Respiratory Infections
- Congenital Heart Disease Studies
- Infant Development and Preterm Care
- Neonatal and fetal brain pathology
- Cardiovascular Conditions and Treatments
- Respiratory viral infections research
- Antifungal resistance and susceptibility
- Birth, Development, and Health
- Corneal surgery and disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Bacterial Infections and Vaccines
- Kawasaki Disease and Coronary Complications
- Streptococcal Infections and Treatments
- Mechanical Circulatory Support Devices
- Intraocular Surgery and Lenses
- Genomic variations and chromosomal abnormalities
- Neuroscience of respiration and sleep
- Cardiac Arrhythmias and Treatments
- Neonatal and Maternal Infections
- Cardiac Structural Anomalies and Repair
- Retinopathy of Prematurity Studies
- Glaucoma and retinal disorders
- Teratomas and Epidermoid Cysts
Chonnam National University Hospital
2014-2024
National Medical Research Center of Dentistry and Maxillofacial Surgery
2024
Seoul National University
2023
Second Affiliated Hospital of Soochow University
2019-2022
Soochow University
2014-2022
Chonnam National University
2007-2021
First Hospital of Jilin University
2010-2018
Jilin University
2010-2018
Statistics Korea
2012
First Bethune Hospital of Jilin University
2012
Incidence of Bronchopulmonary Dysplasia in KoreaA nationwide survey was conducted to determine the incidence bronchopulmonary dysplasia (BPD) Korea and intercenter differences survival BPD rates among preterm infants.Questionnaires were sent all registered neonatal intensive care units (NICUs).The questionnaires inquired about very low birth weight (VLBW, < 1,500 g) infants who had been admitted each NICU from 2007 2008.BPD defined as requiring oxygen at 36 weeks' postmenstrual age.Almost...
Secreted aspartic proteases (Sap), encoded by a family of 10 SAP genes, are key virulence determinants in Candida albicans. Although biofilm-associated bloodstream infections (BSIs) frequently caused C. albicans, gene expression albicans biofilms formed BSI isolates has not been evaluated. We compared the two SAP5 and SAP9, with those from other body sites. Sixty-three were analyzed, comprising 35 28 A denture-strip biofilm model was used, genes quantified real-time RT-PCR during planktonic...
Abstract Background Faced with extremely low fertility rates and increasing numbers of low‐birthweight births in K orea, we examined the factors affecting mortality very‐low‐birthweight ( VLBW ) infants orea. Methods A survey was conducted 91 93 hospitals providing neonatal intensive care orea 2009. Data included information on number unit NICU beds, medical workforce, resources , birth death. Results There approximately one per 4888 births, bed 355 mechanical ventilator 739 incubator 327...
Recent Changes in the Incidence of Bronchopulmonary Dysplasia among Very-Low-Birth-Weight Infants KoreaWe investigated incidence bronchopulmonary dysplasia (BPD) very-low-birthweight (VLBW) infants Korea using Korean Neonatal Network (KNN) data.In total, 2,386 VLBW born from January 2013 to June 2014 were prospectively registered.BPD was defined as supplemental oxygen or positive pressure support at 36 weeks postmenstrual age (PMA).The overall BPD 28.9%, and mortality rate neonatal intensive...
Background:The coronavirus disease-2019 (COVID-19) pandemic has contributed to the change in epidemiology of many infectious diseases.This study aimed establish pre-pandemic pediatric invasive bacterial infection (IBI).Methods: A retrospective multicenter-based surveillance for IBIs been maintained from 1996 2020 Korea.IBIs caused by eight bacteria (Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis, Staphylococcus aureus, Streptococcus agalactiae, pyogenes, Listeria...
There are few published reports concerning the efficacy of oral ibuprofen for treatment patent ductus arteriosus (PDA) in extremely low birth weight (ELBW) infants. Oral was compared to intravenous indomethacin regarding and safety PDA infants weighting less than 1,000 g at birth. This a retrospective study single center. Data on ELBW who had an echocardiographically confirmed were collected. The treated with either or ibuprofen. Rate ductal closure, need additional treatment, drug-related...
The clinical significance of pleural effusion in Mycoplasma pneumoniae (MP) pneumonia children has not yet been elucidated. Herein, we investigated the implications with MP pneumonia. Overall, 150 transferred to a tertiary hospital were enrolled this study. Information on their clinical, laboratory, and radiological features was retrospectively obtained from medical chart reviews. In total, 24 (16.0%) had at time admission. duration fever length hospitalization significantly longer group...
Background: Invasive bacterial infection (IBI) remains a major burden of mortality and morbidity in children. As coronavirus disease 2019 (COVID-19) emerged, stringent nonpharmaceutical interventions (NPIs) were applied worldwide. This study aimed to evaluate the impact NPIs on pediatric IBI Korea. Methods: From January 2018 December 2020, surveillance for IBIs caused by 9 pathogens ( S. pneumoniae , H. influenzae N. meningitidis agalactiae pyogenes aureus Salmonella species, L....
The aims of this study were to observe the respiratory syncytial virus (RSV) hospitalization rate and identify risk factors for RSV infection among infants in Korea born at <35 weeks gestational age who had not previously received palivizumab.We conducted a over 2.5-year period (between April 2007 September 2009) that included premature (<35 age) underwent follow-up during 1 year after discharge from neonatal intensive care unit. Demographic information was collected each subject baseline,...
Diagnosis of Kawasaki disease (KD) is occasionally delayed because it solely based on clinical symptoms. Previous studies have attempted to identify diagnostic biomarkers for KD. Recently, patients with KD were reported elevated serum ferritin levels. We investigated the usefulness level as a biomarker distinguishing from other acute febrile illnesses. Blood samples obtained pediatric (N=77) and those illnesses (N=32) between December 2007 June 2011 measuring various laboratory parameters,...
Nosocomial Candida albicans infections are a significant problem in neonatal intensive care units (NICUs). We investigated the clonality of C. isolates recovered over an 8-year period from neonates at NICU. also validated multilocus sequence typing (MLST) compared with pulsed-field gel electrophoresis (PFGE) for genotyping strains same A total 43 clinical (10 blood, 19 urine, and 14 other) were obtained between 2005 2012. Clonal defined as isolation two or more identical similar genotypes...
Min Joong Jang, M.D.1, Jong Hee Shin, Wee Gyo Lee, M.D.2, Mi-Na Kim, M.D.3, Kyungwon M.D.4,<br> Hye Soo M.D.5, Mi-Kyung M.D.6, Chulhun L. Chang, M.D.7, Hee-Chang Eun Song Song, M.D.1,<br> Hyun M.D., Myung-Geun Soon-Pal Suh, and Dong-Wook Ryang, M.D.. Ann Lab Med 2013;33:167-73. https://doi.org/10.3343/alm.2013.33.3.167
Although milky nipple discharge appears frequently in infants, bloody is a very rare finding. We experienced 4-month-old, breast-fed infant who showed bilateral with no signs of infection, engorgement, or hypertrophy. The infant's hormonal examination and coagulation tests were normal, an ultrasound revealed mammary duct ectasia. symptoms resolved spontaneously within 6 weeks without any specific treatment, except that we advised the mother to refrain from taking herbal medicine. Since such...
The deletion of the distal long arm chromosome 1 is associated with a characteristic facial appearance and pattern malformations. Characteristic manifestations include round face prominent 'cupid's bow' downturned corners mouth, thin vermilion borders lips, upper lip smooth philtrum, short broad nose, epicanthal folds, apparently low-set ears, micrognathia, microcephaly, abnormal hands feet, variable cardiac or genital anomalies, moderate to severe mental retardation, growth retardation....
Prematurity and low birth weight are major factors associated with neonatal morbidity mortality, their incidence is not decreasing despite an annual decrease in the total number of live births Korea.The objective this study was to establish a strategy reduce mortality by analyzing clinical characteristics high-risk infant along causes death.We retrospectively surveyed medical records infants born at Chonnam National University Hospital patients admitted intensive care unit (NICU) for 10...
Purpose: Methylxanthines are commonly used to treat apnea of prematurity.Recent studies have reported that caffeine therapy reduces the rate bronchopulmonary dysplasia (BPD) and improves survival in preterm infant without neuro developmental disabilities.This study was performed compare effects on episodes, adverse morbidity between theophylline groups.Methods: A retrospective 143 infants born at less than 33 weeks gestation treated with (n=54) or (n=89) from 2011 2012.The baseline...
can lead to RV dysfunction and right heart failure.It is associated with poor prognosis.
Incomplete Kawasaki disease (iKD) is considered to be a less complete form of (cKD), and several differences in the laboratory presentations iKD cKD have been noted. We investigated serum procalcitonin levels patients with iKD, cKD, other febrile diseases (a control group). Seventy-seven 24 41 controls admitted our hospital from November 2009 2011 were enrolled present study. obtained four measurements those inflammatory markers each patient. Samples taken for analysis on day diagnosis (thus...
Lung torsion is a very rare event that has been reported in only 9 cases the pediatric literature but not yet Korean infants. We present case of lung after tracheoesophageal fistula repair an infant. Bloody secretion from endotracheal tube and chest radiographs computed tomographic scan results indicated torsion. Emergency exploration 180° right upper lobe (RUL) middle (RML). After detorsion both lobes, some improvement RUL color was observed, change RML could be determined. Although...
Congenital myotonic dystrophy (CMD) is an inherited neuromuscular disorder with cardiac rhythm abnormalities that may occur as a child grows.No report has described complete atrioventricular (AV) block detected in neonate CMD.We floppy infant of 31 +4 weeks gestation AV at birth, who was diagnosed CMD by Southern analysis.She recovered from 32 hr after temporary transcutaneous pacing applied.To the best our knowledge, this first recorded case accompanied during neonatal period.When newborn...
Purpose : Fluconazole prophylaxis for very low birth weight (VLBW) infants has been shown to reduce invasive fungal infection and its mortality. This study aims evaluate the effect of fluconazole in VLBW on incidence mortality infection. Methods with endotracheal intubation central vascular access admitted Neonatal Intensive Care Unit (NICU) at Chonnam University Hospital were enrolled. Twenty eight 7-month baseline period from January July 2005 (‘non-fluconazole group’) compared 29 a 2006...