A5011156333- Emergency and Acute Care Studies
- Asthma and respiratory diseases
- Mobile Health and mHealth Applications
- Healthcare Policy and Management
- Electronic Health Records Systems
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Child and Adolescent Health
- Adolescent and Pediatric Healthcare
- Respiratory and Cough-Related Research
- Hospital Admissions and Outcomes
- Healthcare Systems and Technology
- Digital Mental Health Interventions
- Infant Development and Preterm Care
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Childhood Cancer Survivors' Quality of Life
- Inhalation and Respiratory Drug Delivery
- Respiratory viral infections research
- Heart Failure Treatment and Management
- Healthcare Technology and Patient Monitoring
- Tracheal and airway disorders
- School Health and Nursing Education
- COVID-19 and healthcare impacts
- Healthcare cost, quality, practices
- Patient Satisfaction in Healthcare
Medical University of South Carolina
2016-2025
Pediatrics and Genetics
2014-2018
West Virginia University
1997-1998
Most research to understand postacute sequelae of SARS-CoV-2 infection (PASC), or long COVID, has focused on adults, with less known about this complex condition in children. Research is needed characterize pediatric PASC enable studies underlying mechanisms that will guide future treatment.
Little is known about the clinical factors associated with COVID-19 disease severity in children and adolescents.We conducted a retrospective cohort study across 45 US children's hospitals between April 2020 to September of pediatric patients discharged primary diagnosis COVID-19. We assessed hospitalization (eg, admission inpatient floor, intensive care unit [ICU], ICU mechanical ventilation, shock, death) among those hospitalized.Among 19,976 encounters, 15,913 (79.7%) were from emergency...
The impact of COVID‐19 public health interventions on pediatric illnesses nationwide is unknown. We performed a multicenter, cross‐sectional study encounters at 44 children's hospitals in the United States to assess changes healthcare utilization during pandemic. pandemic was associated with substantial reductions for respiratory diseases; these large were consistent across illness subgroups. Although nonrespiratory diseases decreased as well, more modest and varied by age. Encounters among...
The coronavirus disease 2019 (COVID-19) pandemic has led to changes in health care use, including decreased emergency department visits for children. In this study, we sought describe the impact of COVID-19 on inpatient use within children's hospitals.We performed a retrospective study using Pediatric Health Information System. We compared and clinical outcomes children 0 18 years age during period (March 15 August 29, 2020) same time frame previous 3 (pre-COVID-19 period). Adjusted...
ABSTRACT Individuals living in rural or medically underserved areas (MUA) with chronic obstructive pulmonary disease (COPD) face significant barriers to specialised care, including pulmonologists, diagnostic spirometry, and rehabilitation. Remote spirometry for screening monitoring may mitigate access contribute improved COPD management this population. This study protocol describes the proposed implementation of a Mobile Health (mHealth) intervention using Bluetooth‐enabled portable...
Like their adult counterparts, pediatric hospitals are increasingly at risk for financial penalties based on readmissions. Limited information is available how the composition of a hospital's patient population affects performance this metric and hence reimbursement providing care. We sought to determine whether applying different readmission metrics differentially hospital characteristics patients serves.We performed cross-sectional analysis 64 children's from Children's Hospital...
Background Asthma is a common chronic pediatric disease that can negatively impact children and families. Self-management strategies are challenging to adopt but critical for achieving positive outcomes. Mobile health technology may facilitate self-management of asthma, especially as adolescents mature assume responsibility their disease. Objective This study aimed explore the perceptions youths with high-risk asthma caregivers on use smartphone app, Smartphone Management System, in...
Objective: To determine if the asthma medication ratio predicts subsequent emergency department (ED) visits and hospital admissions in children. Design:Retrospective cohort with two year pairs.Setting/Participants: 2007-2009 South Carolina Medicaid recipients persistent age 2-18.M ain Exposure: C ontrol ler-to-total ast hma ratios were calculated for each patient 2007 2008.Ratios range from 0-1 (1 = ideal, 0 no controller).Outcome Measures: 2008 2009 related ED visits, hospitalizations, a...
BACKGROUND AND OBJECTIVE: The hospital-to-hospital transfer of pediatric patients is a common practice that poorly understood. To better understand this practice, we examined national database to profile interfacility transfers. METHODS: We used the 2012 Kids’ Inpatient Database examine characteristics hospitalized (<21 years; excluding pregnancy diagnoses) with admission source. performed descriptive statistics compare patient characteristics, utilization, and hospital between those...
The effect electronic health record (EHR) implementation has on physician satisfaction and patient care remains unclear. A better understanding of perceptions EHRs factors that influence those is needed to improve the experience when using EHRs.The objective this study was determine provider clinical practice associated with EHR perception impact.We surveyed a random sample physicians, including residents fellows, at US quaternary academic hospital from February March 2016. survey assessed...
BACKGROUND Although pediatric health care use declined during the coronavirus disease 2019 (COVID-19) pandemic, impact on children with complex chronic conditions (CCCs) has not been well reported. OBJECTIVE To describe of pandemic inpatient and outcomes for CCCs. METHODS This multicenter cross-sectional study used data from Pediatric Health Information System. We examined trends in admissions between January 2020 through March 2021, comparing them to same timeframe previous 3 years...
ABSTRACT Two models for the mechanism of retroviral recombination have been proposed: forced copy choice (minus-strand recombination) and strand displacement-assimilation (plus-strand recombination). Each minus-strand event results in one template switch, whereas each plus-strand two switches. Recombinant proviruses with more than switches were previously observed. Recombinants switch generated by recombination, while recombinants containing may or correlated recombination. We recently...
Background: Youth with asthma who have poor medication adherence, limited access to care, and are frequently seen in the acute care setting often termed "high risk."
Many children's hospitals are actively working to reduce readmissions improve care and avoid financial penalties. We sought determine if pediatric readmission rates have changed over time. used data from 66 in the Inpatient Essentials Database including index hospitalizations January, 2010 through June, 2016. Seven‐day all cause (AC) potentially preventable (PPR) were calculated using 3M PPR software. Total condition‐specific quarterly AC generated for each hospital aggregate. included 4.52...
Dyspnea is an unpredictable and distressing symptom of chronic obstructive pulmonary disease (COPD).Dyspnea challenging to measure due the heterogeneity COPD recall bias associated with retrospective reports.Ecological Momentary Assessment (EMA) a technique used collect symptoms in real-time within natural environment, useful for monitoring trends risks exacerbation COPD.EMA can be integrated into mobile health (mHealth) platforms repeated data collection alongside physiological measures...
Objective: To assess the current state of research productivity, goals, obstacles, and needs pediatric hospitalists. Methods: The American Academy Pediatrics Section on Hospital Medicine performed a cross-sectional online survey Questions assessed demographics, system-level factors, interests, goals perceived need for training support. Results: Two hundred twenty hospitalists in United States completed survey. Of these, 56% had presented at national meeting, 24% were first authors an article...
Youth with multi-morbidity (one or more chronic diseases) are at increased risk of further morbidity and early mortality as they enter their adult years. Recent increases in both asthma obesity among youth have led to high health care utilization, related complications, expanded risks subsequent cardiovascular disease burden. Common symptoms seen include fatigue, pain, depression, anxiety. These can result decreased physical activity, social isolation, poor quality life, which also may...
During reverse transcription, minus-strand DNA transfer connects the sequences located at two ends of viral RNA to generate a long terminal repeat. It is thought that homology in repeat (R) regions facilitate transfer. In this report, effects diminished R-region on synthesis and virus titer were examined. A retrovirus vector, PY31, was constructed contain 5' 3' cis-acting elements from Moloney murine sarcoma spleen necrosis virus. These viruses are genetically distinct, R little homology....