A5101603668- Congenital gastrointestinal and neural anomalies
- Tissue Engineering and Regenerative Medicine
- Renal and related cancers
- Digestive system and related health
- Urological Disorders and Treatments
- Congenital Diaphragmatic Hernia Studies
- Congenital Anomalies and Fetal Surgery
- Hernia repair and management
- Organ Transplantation Techniques and Outcomes
- Intestinal Malrotation and Obstruction Disorders
- Spinal Cord Injury Research
- Mitochondrial Function and Pathology
- Phagocytosis and Immune Regulation
- Wnt/β-catenin signaling in development and cancer
- Immune cells in cancer
- Head and Neck Surgical Oncology
- Lower Extremity Biomechanics and Pathologies
- Autophagy in Disease and Therapy
- Thermal Regulation in Medicine
- Cancer Research and Treatments
- Intestinal and Peritoneal Adhesions
- Sinusitis and nasal conditions
- Gastric Cancer Management and Outcomes
- Color Science and Applications
- Adenosine and Purinergic Signaling
China Medical University
2008-2025
Anhui Medical University
2022
Ministry of Education of the People's Republic of China
2022
Zhongshan Hospital of Xiamen University
2021
Fudan University
2021
First Affiliated Hospital of Harbin Medical University
2021
Harbin Medical University
2021
Fu Wai Hospital
2020
Shanghai Institute of Technical Physics
2018
Guangzhou Medical University
2017
Abstract Objective Despite a great number of studies analysing the effects microgravity on stem cell proliferation and differentiation, few them have focused real‐time imaging estimates in space. Herein, we utilized TZ ‐1 cargo spacecraft, automatic culture equipment live techniques to examine real differentiation mouse embryonic cells ( mESC s). Materials methods Oct4‐ GFP , Brachyury‐ ‐derived EB s were used as experimental samples spaceflight mission. These seeded into chambers, cultured...
Osteoarthritis (OA) is a heterogeneous disease that consistently difficult to treat due the complexity of regulatory network involved in OA pathogenesis, especially terms cartilage degeneration. As C-2 epimer glucose, d-mannose can alleviate bone loss and repress immunopathology by upregulating T cells; however, role OA-related degeneration remains unknown. In this study, we investigated chondroprotective effect vitro vivo on OA. We found incubating interleukin (IL)-1β-treated rat...
Abstract Chronic pancreatitis (CP) is described as progressive inflammatory fibrosis of pancreas, accompanied with irreversible impaired endocrine and exocrine insufficiency. Pancreatic stellate cells (PSCs) are widely distributed in the stroma pancreas PSCs activation has been shown one leading causes for pancreatic fibrosis. Our previous study revealed that autophagy dramatically activated CP tissues, which facilitates Long non-coding RNAs (LncRNAs) have recognized crucial regulators...
P53 is known as a transcription factor to control apoptotic cell death through regulating series of target genes in nucleus. There accumulating evidences show that p53 can directly induce apoptosis independent way at mitochondria. However, the mechanism by which translocation into mitochondria response oxidative stress remains unclear. Here, glucose oxidase (GOX) was used ROS generation HepG2 cells and liver tissues mice. The results showed stabilized translocated time dose dependent manner...
A retrospective review.The aim of this study was to discuss the characteristics, treatment, and incidence surgical site infection (SSI) following transoral approach surgery.One primary risks associated with surgery is postoperative SSI. Few reports exist detailing specific circumstances, treatment options, SSIs in a large series consecutive cases.From January 2005 September 2010, 172 surgeries were performed at single tertiary referral center. Information on patients, methods, complication...
Background: Anorectal malformations (ARMs) represent a variety of congenital disorders that involve abnormal termination the anorectum.This study was to reveal relation between CDX1 and human ARMs phenotypes.Methods: 108 Chinese patients 120 controls were included in this study.We analyzed two by PCR, qRT-PCR, western blot immunofluorescence.Results: Four heterozygous mutations gene identified (3.7%, 4/108), no found controls.CDX1 protein expression significantly decreased compared with...
Background. The objectives of this study were to determine the spatiotemporal distribution human caudal-type homeobox proteins CDX1, CDX2 and CDX4 during development hindgut anorectum in embryo explore possible roles CDX genes morphogenesis anorectum. Methods. Embryos (89) cut into sections serially sagittally. From gestation weeks 4-9, detected on caudal midline by immunohistochemical staining. Results. During week 4, extensive immunoreactivity was dorsal urorectal septum, urogenital sinus...
Objective To evaluate the effect of methylprednisolone on hepatic ischemia-reperfusion (I/R) injury in patients undergoing hepatolobectomy.Methods Sixty ASA physical status Ⅱ or Ⅲ patients,aged 30-64 yr,weighing 45-75 kg,scheduled for elective hepatolobectomy,were randomized to control group (n =30 each).After induction anesthesia,methylprednisolone 500 mg (in 100 ml normal saline) was infused intravenously at 5 ml/min before skin incision M.Anesthesia induced with propofol,fentanyl and...