A5076527916- Fish Ecology and Management Studies
- Advanced Proteomics Techniques and Applications
- Aquatic Invertebrate Ecology and Behavior
- Metabolomics and Mass Spectrometry Studies
- Cannabis and Cannabinoid Research
- Marine and fisheries research
- Tryptophan and brain disorders
- Mass Spectrometry Techniques and Applications
- Long-Term Effects of COVID-19
- Pancreatic function and diabetes
- Fish biology, ecology, and behavior
- Ubiquitin and proteasome pathways
- Enzyme Production and Characterization
- Fish Biology and Ecology Studies
- Environmental DNA in Biodiversity Studies
- Blood properties and coagulation
- Gut microbiota and health
- Neurogenesis and neuroplasticity mechanisms
- COVID-19 Clinical Research Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Water Quality and Resources Studies
- Epigenetics and DNA Methylation
- COVID-19 and Mental Health
- Transgenic Plants and Applications
- Nuclear Receptors and Signaling
Universidade Estadual de Campinas (UNICAMP)
2017-2025
United States Fish and Wildlife Service
2017-2024
South Dakota State University
2016-2019
Digital Proteomics (United States)
2012
Although increasing evidence confirms neuropsychiatric manifestations associated mainly with severe COVID-19 infection, long-term dysfunction (recently characterized as part of "long COVID-19" syndrome) has been frequently observed after mild infection. We show the spectrum cerebral impact acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ranging from alterations in mildly infected individuals (orbitofrontal cortical atrophy, neurocognitive impairment, excessive fatigue and anxiety...
Abstract Visceral adiposity is a risk factor for severe COVID-19, and link between adipose tissue infection disease progression has been proposed. Here we demonstrate that SARS-CoV-2 infects human undergoes productive in fat cells. However, susceptibility to the cellular response depends on anatomical origin of cells viral lineage. express more ACE2 are susceptible than their subcutaneous counterparts. leads inhibition lipolysis cells, while visceral it results higher expression...
Long-term sequelae of coronavirus disease (COVID)-19 are frequent and major concern. Severe acute respiratory syndrome 2 (SARS-CoV-2) infection affects the host gut microbiota, which is linked to severity in patients with COVID-19. Here, we report that microbiota post-COVID subjects had a remarkable predominance Enterobacteriaceae strains an antibiotic-resistant phenotype compared healthy controls. Additionally, short-chain fatty acid (SCFA) levels were reduced feces. Fecal transplantation...
Abstract Although increasing evidence confirms neuropsychiatric manifestations associated mainly with severe COVID-19 infection, the long-term dysfunction has been frequently observed after mild infection. Here we show spectrum of cerebral impact SARS-CoV-2 infection ranging from alterations in mildly infected individuals (orbitofrontal cortical atrophy, neurocognitive impairment, excessive fatigue and anxiety symptoms) to acute damage confirmed brain tissue samples extracted orbitofrontal...
ABSTRACT Oligodendrocytes, the myelinating cells in central nervous system, are implicated several neurological disorders marked by dysfunctional RNA–binding proteins (RBPs). The present study aimed at investigating role of hnRNP A1 proteome corpus callosum, prefrontal cortex, and hippocampus a murine cuprizone–induced demyelination model. Right after cuprizone insult, we administered an splicing activity inhibitor analyzed its impact on brain remyelination nanoESI‐LC‐MS/MS label‐free...
Abstract Background Schizophrenia is a complex and severe neuropsychiatric disorder, with wide range of debilitating symptoms. Several aspects its multifactorial complexity are still unknown, some accepted to be an early developmental deficiency more specifically neurodevelopmental origin. Understanding the timepoints disturbances during neural cell differentiation processes could lead insight into development disorder. In this context, human brain organoids cells differentiated from...
The transglutaminase-catalysed incorporation of putrescine and monodansylcadaverine into yeast phosphoglycerate kinase has been studied. There is little the amines wild-type enzyme, but nearly stoichiometric histidine-388----glutamine mutant enzyme. C.d. studies show that overall structure enzyme very similar to Incorporation causes no significant change in its activity. Glutamine-388 was shown, by isolation sequencing modified peptide, be site specificity transglutaminase reaction discussed...
Abstract The American Fisheries Society (AFS) has recommended standard gears and methods for collecting North freshwater fish data, but selectivity of these gears, including gill nets, is poorly described most species. We calculated contact species commonly collected with AFS nets in lakes reservoirs America, Black Bullhead Ameiurus melas , Channel Catfish Ictalurus punctatus Walleye Sander vitreus Yellow Perch Perca flavescens . normal curve provided the best fit to empirical catch data all...
<title>Abstract</title> Background There is mounting evidence that SARS-CoV-2 targets tissues beyond the respiratory tract. Long-term sequelae after COVID-19 are frequent and of major concern. Prolonged virus detection in gut has been particularly intriguing. Of note, infection also disturbs microbiota composition, a finding linked with disease severity patients COVID-19. Here, we aimed to characterize functional role long-term consequences To this end, characterized from human subjects...
The transglutaminase-catalysed incorporation of primary amines (putrescine and monodansylcadaverine) into bovine beta-lactoglobulin has been studied. In the presence 1 mM-dithiothreitol between 2 mol amine can be incorporated per subunit. There is very little in absence reducing agent. By isolating sequencing modified peptides, sites modification have identified as Gln-159 (preferred) Gln-155. C.d. used to study structure over a range pH values or dithiothreitol. results are discussed terms...
Abstract The COVID-19 pandemic was initiated by the rapid spread of a SARS-CoV-2 strain. Though mainly classified as respiratory disease, infects multiple tissues throughout human body, leading to wide range symptoms in patients. To better understand how affects proteome from cells with different ontologies, this work generated an infectome atlas 9 cell models, including brain, blood, digestive system, and adipocyte tissue. Our data shows that infection trigger dysregulations on proteins...
Abstract We performed a field experiment in five eastern South Dakota lakes to investigate fish escapement differences between modified fyke nets with two common throat configurations (restricted and unrestricted). Nets restricted unrestricted throats were deployed pairs for 24 h on similar habitat. Captured measured TL given day‐specific marks. The paired redeployed, marked randomly assigned be stocked into the or net h; stocking densities (stratified low, medium, high) species specific....
More than half of the diminutive North American catfish species known as madtoms (Noturus spp.) are considered imperiled due to range reductions from habitat fragmentation and degradation. In response, government agencies regularly conduct sampling that targets these cryptic fishes. Unfortunately, effectiveness biases associated with common gears has rarely been quantified for non-game fish, including madtoms. To improve protocols diverse madtom species, we: (a) detection probabilities...
Abstract There is a constant interest in blood‐based protein biomarkers, which can help to improve diagnosis and treatment outcomes of multifactorial human pathologies. In this regard, proteomic studies usually employ plasma immunoaffinity fractionation deplete the most abundant proteins, due high dynamic concentration range proteins. The depletion proteins allows obtain less and, oftentimes, more interesting However, removal fraction ‐ depletome may co‐elute many unintended protein‐protein...
Abstract We performed a gear comparison between three types of paired fyke nets used to monitor fish communities in the nearshore zone Lake Michigan. Our objective was identify single net design that would maximize species diversity and catch. The included small frame model with 3‐mm bar mesh (Mini‐fyke), larger‐framed 13‐mm (Fyke), large recommended by American Fisheries Society (AFS‐fyke). set all triplicate on similar littoral habitat at 16 sites Green Bay, an embayment Total catch...