Adriano Abbud
A5082378801- SARS-CoV-2 and COVID-19 Research
- Mosquito-borne diseases and control
- Marine Biology and Ecology Research
- Bacillus and Francisella bacterial research
- Viral Infections and Outbreaks Research
- SARS-CoV-2 detection and testing
- Viral Infections and Vectors
- Poxvirus research and outbreaks
- COVID-19 epidemiological studies
- Virology and Viral Diseases
- Crustacean biology and ecology
- COVID-19 Clinical Research Studies
- Collembola Taxonomy and Ecology Studies
- COVID-19 diagnosis using AI
- vaccines and immunoinformatics approaches
- Phytoplasmas and Hemiptera pathogens
- Healthcare Regulation
- Coral and Marine Ecosystems Studies
- Animal Virus Infections Studies
- HIV Research and Treatment
- Healthcare during COVID-19 Pandemic
- Parasite Biology and Host Interactions
- Malaria Research and Control
- Herpesvirus Infections and Treatments
- Geography and Environmental Studies
Instituto Adolfo Lutz
2021-2024
Secretaria da Saúde
2022
Universidade de São Paulo
2009
Arthropod-borne viruses (arboviruses) are transmitted by arthropod vectors to humans, leading disease outbreaks mainly in tropical regions of the world.1Weaver SC Charlier C Vasilakis N Lecuit M Zika, chikungunya, and other emerging vector-borne viral diseases.Annu Rev Med. 2018; 69: 395-408Crossref PubMed Scopus (234) Google Scholar Although many arboviruses known, three Aedes-spp-borne particularly concerning for humans at a global scale due recurring large expanding epidemic dengue virus,...
Abstract Latin America and Caribbean (LAC) regions were an important epicenter of the COVID-19 pandemic SARS-CoV-2 evolution. Through Genomic Surveillance Regional Network (COVIGEN), LAC countries produced number genomic sequencing data that made possible enhanced surveillance capacity in Americas, paving way for characterization emerging variants helping to guide public health response. In this study we analyzed approximately 300,000 sequences generated between February 2020 March 2022 by...
Mutations at both the receptor-binding domain (RBD) and amino (N)-terminal (NTD) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike (S) glycoprotein can alter its antigenicity promote immune escape. We identified that SARS-CoV-2 lineages circulating in Brazil with mutations concern RBD independently acquired convergent deletions insertions NTD S protein, which altered antigenic-supersite other predicted epitopes this region. Importantly, we detected community transmission...
The SARS-CoV-2 variant of concern (VOC) Delta was first detected in India October 2020. imported cases the Brazil were identified April 2021 southern region, followed by more different regions during following months. By early September 2021, already dominant southeastern (87%), (73%), and northeastern (52%) Brazilian regions. This study aimed to understand spatiotemporal dissemination dynamics Brazil. To this end, we employed a combination maximum likelihood (ML) Bayesian methods...
COVID-19 vaccination began in São Paulo, Brazil January 2021, first targeting healthcare workers (HCWs) and the elderly, using CoronaVac vaccine (Sinovac/Butantan) subsequently Oxford/AstraZeneca (ChAdOx1) (AstraZeneca/FIOCRUZ-RJ). Studies on such vaccines have shown efficacy preventing severe cases deaths, but there is a lack of information regarding their effectiveness. This manuscript presents data from Instituto Adolfo Lutz (IAL), public health laboratory located Paulo City that receives...
Abstract Mutations at both the receptor-binding domain (RBD) and amino (N)-terminal (NTD) of SARS-CoV-2 Spike (S) glycoprotein can alter its antigenicity promote immune escape. We identified that lineages circulating in Brazil with mutations concern RBD independently acquired convergent deletions insertions NTD S protein, which altered antigenic-supersite other predicted epitopes this region. Importantly, we detected communitary transmission four bearing indels: a P.1 Δ69-70 lineage (which...
Mpox is caused by a zoonotic orthopoxvirus capable of infecting several animal species, including humans. The analysis cases in the current outbreak showed that, differently from what happens classical disease, mpox has mostly affected men who have sex with (MSM) and bisexuals, high proportion people living HIV/AIDS. role immune system fighting been discussed literature experts believe that immunity conferred natural infection may be lifelong, advocating against possibility reinfection...
Recombination events have been described in the Coronaviridae family. Since beginning of SARS-CoV-2 pandemic, a variable degree selection pressure has acted upon virus, generating new strains with increased fitness terms viral transmission and antibody scape. Most SC2 variants concern (VOC) detected so far carry combination key amino acid changes indels. may also reshuffle existing genetic profiles distinct strains, potentially giving origin to recombinant altered phenotypes. However,...
New-generation sequencing (NGS) techniques have brought the opportunity for genomic monitoring of several microorganisms potentially relevant to public health. The establishment different methods with mechanisms provides a wide choice, taking into account aspects. With that in mind, present aim study was compare basic metrics could impact genotyping by nanopores from Oxford Nanopore Technologies and synthesis Illumina clinical samples positive Chikungunya (CHIKV). Among studied, running...
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Genomics can bring valuable information for tracking transmission and evolution of pathogens, COVID-19 is showing that it a tool rapid response to overcome the SARS-CoV-2.1Lo SW Jamrozy D. epidemiological surveillance.Nat Rev Microbiol. 2020; 18: 478Crossref PubMed Scopus (23) Google Scholar By end August 2021, more than 3·1 million sequences have been shared through Global Initiative on Sharing Avian Influenza Data (GISAID), in an effort towards open data sharing.2Shu Y McCauley J. GISAID:...
Chikungunya virus (CHIKV), a mosquito-borne alphavirus, has traditionally circulated in Africa and Asia, causing human febrile illness accompanied by severe, chronic joint pain. The Asian East-Central-South African (ECSA) genotypes were introduced Brazil 2014, Bahia State Northeast region. CHIKV rapidly spread, epidemics urban areas, the ECSA genotype was detected also other regions. In last five years, more than 700,000 cases of fever reported Brazil. Nevertheless, there is limited...
Three new species of serpulids from Brazil are described herein, two which were described, but not named, by Zibrowius here considered as and given specific names. Vermiliopsis zibrowii sp. nov. is characterized an operculum with a single endplate or several septa progressively nearer to each other towards the tip separated conspicuous ribs. Pseudovermilia harryi has short ribs its tube different similar congeners. Filogranula revizee sunken funnel and, frequently, slender, distally sharp...