A5026233845- Pneumonia and Respiratory Infections
- Algal biology and biofuel production
- Lipid metabolism and biosynthesis
- Atmospheric chemistry and aerosols
- Respiratory viral infections research
- Marine and coastal ecosystems
- Microbial Metabolic Engineering and Bioproduction
- SARS-CoV-2 and COVID-19 Research
- Genomics and Phylogenetic Studies
- Viral-associated cancers and disorders
- Aquaculture disease management and microbiota
- Pneumocystis jirovecii pneumonia detection and treatment
- Biofuel production and bioconversion
- Bacterial Infections and Vaccines
- Neurobiology and Insect Physiology Research
- Plant Stress Responses and Tolerance
- Plant-Microbe Interactions and Immunity
- Parvovirus B19 Infection Studies
- Insect Utilization and Effects
- Plant Pathogenic Bacteria Studies
- Tuberculosis Research and Epidemiology
- Infection Control and Ventilation
- Invertebrate Immune Response Mechanisms
- Nitrogen and Sulfur Effects on Brassica
- Heme Oxygenase-1 and Carbon Monoxide
Children's Hospital of Zhejiang University
2020-2025
Air Force Medical University
2013-2024
Xijing Hospital
2023-2024
Changsha University of Science and Technology
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2022
Huazhong University of Science and Technology
2022
Hubei Water Resources Research Institute
2022
Jilin Agricultural University
2018
International Flavors & Fragrances (United States)
2017
China Tobacco
2014-2016
In locusts, olfaction plays a crucial role for initiating and controlling behaviours, including food seeking aggregation with conspecifics, which underlie the agricultural pest capacity of animals. this context, molecular basis in these insects is particular interest. Here, we have identified genes two orthopteran species, Locusta migratoria Schistocera gregaria, encode olfactory receptor co-receptor (Orco). It was found that sequences LmigOrco SgreOrco share high degree identity to each...
Nonbacterial respiratory pathogens are major acute infection (ARI) agents in children. We aimed to characterize the epidemiological changes 11 common nonbacterial after easing COVID-19 restrictions Zhejiang, China, guide prevention and treatment. A retrospective study was conducted on children with ARIs at Children’s Hospital, Zhejiang University School of Medicine 2023, characteristics were analyzed for gender, age, month, sampling method, immune status. In total, 59.48% identified...
To investigate the distribution and risk factors associated with drug-resistant tuberculosis (TB) at a local hospital in Northeast China.A total of 205 patients TB were enrolled study from March 8, 2010 to July 13, 2011. Mycobacterium (MTB) strains isolated subjected drug susceptibility testing by proportion method.Among MTB, 54 (26.3%) had isolates that showed resistance least one drug. The overall prevalence multidrug-resistant (MDR-TB) was 6.8% (n = 14) (3.0% newly diagnosed 22.0%...
Carthamus tinctorius L. commonly known as safflower is an important oilseed crop containing oil bodies. Oil bodies are intracellular organelles in plant cells for storing triacylglycerols (TAGs) and sterol esters. Oleosins the most surface proteins of We predicted retrieved sequences eight putative Ct-oleosin (Carthamus tinctorius-oleosin) genes from genome database safflower. The bioinformatics analyses revealed size their open reading frames ranging 414 to 675 bp, encoding 137 224 aa...
Epstein-Barr virus (EBV) infection occurs commonly in children and presents as a primary or reactivated infection, which are difficult for clinicians to distinguish. This study investigated the clinical characteristics of two types infections. Children with detectable plasma EBV-DNA were retrospectively enrolled divided into group by EBV-specific antibody. We analyzed patients' characteristics, manifestations, complications, inflammatory biomarkers, viral load. A total 9.3% reactivation...
We have isolated mutations defining a new gene, tlp-1, that affect asymmetric cell fates and morphogenesis during the development of C. elegans tail. tlp-1 cause defects in specification descendants T blast cell, whose polarity is controlled by Wnt signaling abnormal male tail leading to formation posterior protrusion reminiscent ‘leptoderan’, or pointy tailed, nematode species. In wild-type males, which ‘peloderan’ rounded tail, retraction tip hypodermis involves temporally ordered set...
Olfaction in animals is important for host localization, mating and reproduction heterogeneous chemical environments. Studying the molecular basis of olfactory receptor neurons (ORNs) systems can elucidate evolution olfaction associated behaviours. Odorant receptors (ORs) insects have been identified, particularly holometabolous model Drosophila, some them functionally studied. However, ORs locust-a hemimetabolous insect most crop pest-have not yet hindering our understanding locust...
Docosahexaenoic acid (DHA) is an important omega-3 polyunsaturated fatty (PUFA) that plays a critical physiological role in human health. Schizochytrium sp. considered excellent strain for DHA production, but the synthesis of limited by availability nicotinamide adenine dinucleotide phosphate (NADPH). In this study, endogenous glucose-6-phosphate dehydrogenase (G6PD) gene was overexpressed H016. Results demonstrated G6PD overexpression increased NADPH, which ultimately altered profile,...
With the lifting of coronavirus disease 2019 (COVID-19) restrictions in December 2022 China, population was widely infected with COVID-19. We aim to analyzed changes epidemiological characteristics other respiratory pathogens children before and after COVID-19 pandemic. conducted a retrospective analysis 44 704 acute infections who underwent 11 pathogen tests based on multiplex polymerase chain reaction between February both 2023. The total detection rate (24861, 74.80% vs. 6423, 56.01%; p =...
Two strains of Gram-stain-positive, aerobic, non-motile, irregular coccus-shaped bacteria, designated YIM 2617T and 2617-2, were isolated from the root Ocimum basilicum. Phylogenetic analysis on basis 16S rRNA gene sequence comparison revealed that two closely related to Mariniluteicoccus flavus M13146T (98.1 98.0 % similarities, respectively) formed a robust clade with M. in neighbour-joining tree. Optimum growth was observed at 28-32 °C, pH 7.0-8.0 presence 0-2 (w/v) NaCl. The...
Objective To investigate the characteristics of hosts, antimicrobial susceptibility, and molecular epidemiology mucoid serotype 3 Streptococcus pneumoniae ( S. ) isolated from children in China. Method isolates collected between January 2016 December 2019 were analyzed. with phenotype selected visually, confirmed by Quellung reaction. The susceptibility was measured E-test. Multilocus sequence typing used for clonal analysis. Results Twenty (3.04%) identified 657 clinical isolates, all them...
Abstract 31 P NMR analysis of samples prepared in a sodium cholate detergent system was used as method for the identification and quantification enzymatic hydrolysis products lecithin. To precisely characterize all from commercial lecithin, series reactions each phospholipid with phospholipase PLA1 were conducted monitored by at different times. Twenty‐six phosphorus‐containing six classes phospholipids (PC, PI, PS, PE, PG, PA) found determined measurement. The impact pH on chemical shift...
Abstract Background Perilipin 5 (Plin5) is well known to maintain the stability of intracellular lipid droplets (LDs) and regulate fatty acid metabolism in oxidative tissues. It highly expressed heart, but its roles have yet be fully elucidated. Methods Plin5-deficient mice Plin5/leptin-double-knockout were produced, their histological structures myocardial functions observed. Critical proteins related glucose measured heart tissues, neonatal mouse cardiomyocytes Plin5-overexpressing H9C2...
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Isocitrate dehydrogenase (IDH) mutations frequently occur in lower-grade gliomas and secondary glioblastomas. Mutant IDHs exhibit a gain-of-function activity, leading to the production of D-2-hydroxyglutarate (D-2HG) by reducing α-ketoglutarate (α-KG), central player metabolism epigenetic modifications. However, role α-KG homeostasis IDH-mutated gliomagenesis remains elusive. In this study, we found that low expression oxoglutarate (OGDH) was common feature gliomas, as well astrocytes. This...
In recent years, the outbreak of infectious diseases has highlighted need for improved planning hospital buildings. Traditional disease hospitals only considers impact wind and pollutant diffusion, without analysing diffusion under different thermal conditions. To reveal distribution pollutants in conditions, this study conducted tunnel tests numerical analyses environment surrounding an Changsha, China. The results show that concentration mainly depends on local speed. range Rb = −1.25 to...