A5036688483- Occupational and environmental lung diseases
- Autoimmune Neurological Disorders and Treatments
- Electrolyte and hormonal disorders
- Renal function and acid-base balance
- Infectious Encephalopathies and Encephalitis
- Polyomavirus and related diseases
- Cytomegalovirus and herpesvirus research
- Tuberous Sclerosis Complex Research
- Parasitic infections in humans and animals
- earthquake and tectonic studies
- Peripheral Neuropathies and Disorders
- Geological and Geochemical Analysis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Epilepsy research and treatment
- Global Financial Regulation and Crises
- Pathogenesis and Treatment of Hiccups
- Potassium and Related Disorders
- Tumors and Oncological Cases
- Neurological diseases and metabolism
- COVID-19 Clinical Research Studies
- Fetal and Pediatric Neurological Disorders
- Medicinal Plants and Neuroprotection
- Occupational exposure and asthma
- Amyotrophic Lateral Sclerosis Research
- Advanced Data Storage Technologies
Minzu University of China
2023-2025
Sichuan University
2009-2024
West China Hospital of Sichuan University
2009-2024
University of Electronic Science and Technology of China
2024
Guangzhou Institute of Geochemistry
2024
Chinese Academy of Sciences
2024
University of Chinese Academy of Sciences
2024
Shanghai Xuhui Central Hospital
2023
University of Hong Kong
2023
Guizhou Provincial People's Hospital
2023
Summary Objective To evaluate the long‐term seizure outcome and potential factors associated with in patients anti‐ N ‐methyl‐ d ‐aspartate receptor (anti‐ NMDAR ) encephalitis. Methods In setting of a prospective, single‐center, longitudinal cohort study, 109 were evaluated ongoing follow‐up. Patients underwent clinical evaluation every 3 months. Seizure outcomes risk assessed median follow‐up 24 months (6–60 months). Results Of (47 men; 62 women) encephalitis, 88 (80.7%) had reported...
<title>Abstract</title> The full text of this preprint has been withdrawn, as it was submitted in error. Therefore, the authors do not wish work to be cited a reference. Questions should directed corresponding author.
<h3>Background:</h3> Swallowing dysfunction is common and disabling after acute stroke; however, the mechanism of dysphagia or recovery swallowing from remains uncertain. The purpose this study was to explore cerebral activation in using functional MRI (fMRI) compare anatomy unilateral hemispheric stroke patients healthy adults. <h3>Methods:</h3> In total, five left with dysphagia, right 10 controls were examined event related fMRI while laryngeal swallow movements recorded. Data processed...
Background Anti-N-methyl-D-aspartate receptor encephalitis (NMDARE) is a severe autoimmune disorder with high morbidity and mortality. Current treatments have limitations including relapse, highlighting the need for effective maintenance therapy. This study evaluates efficacy safety of mycophenolate mofetil (MMF) as long-term adjunctive therapy to first-line treatment in newly diagnosed patients NMDARE. Methods We conducted prospective, randomised, open-label trial four academic centres...
Silicosis is characterized by chronic lung inflammation and fibrosis, which are extremely harmful to human health. The pathogenesis of silicosis involves uncontrolled immune processes. Evidence supports that regulatory B cells (Bregs) produce negative cytokines, such as IL-10, can negatively regulate responses in autoimmune diseases. Our previous study found IL-10-producing (B10) were involved the development silica-induced fibrosis mice. However, little known about role patients. In this...
Abstract Background Tuberous sclerosis complex (TSC) is a rare multisystem autosomal dominant disorder caused by pathogenic variants in either the TSC1 or TSC2 gene. Common manifestations of TSC have been grouped into major and minor clinical diagnostic criteria assessed routine workup. However, case studies point towards existence disease to potential association with malignant tumors. In this study we sought characterize malignancies using large cohort patients. Methods TuberOus SClerosis...
Abstract Background and purpose The aim was to investigate the neurological complications associated with coronavirus disease 19 (COVID‐19) during 2022 Omicron wave. Methods analysis medical records of a cohort people admitted wards three participating tertiary centres in Sichuan from 12 December January 2023 were reviewed. Demographics clinical data obtained analysed an interest COVID‐19‐related new‐onset or worse symptoms. current also compared two similar same period months earlier....
The Value of High Resolution Computed Tomography in the Diagnostics Small Opacities and Complications Silicosis Mine Machinery Manufacturing Workers, Compared to Radiography: Jinkai S un , et al . Division Pneumoconiosis, School Public Health, China Medical University, —The purpose this study was assess value usefulness high resolution computed tomography (HRCT) diagnostics small opacities complications silicosis mine machinery manufacturing workers, compared conventional radiograms....
As a review and clinical analysis of primary oral leiomyosarcoma (LMS) cases in West China stomatology Hospital the past 37 years, this study provides demographic, therapeutic prognostic information rare tumor.In our study, 20 LMS treated between 1972 2008 Stomatology were analyzed retrospectively. A thorough records was carried out potential indicators survival analyzed.The most common symptom presented as painless mass. The median age patients peak incidence tumor 2nd 5th decades. There no...
Abstract Background Tuberous sclerosis complex (TSC)-associated neuropsychiatric disorders (TAND) have unique, individual patterns that pose significant challenges for diagnosis, psycho-education, and intervention planning. A recent study suggested it may be feasible to use TAND Checklist data data-driven methods generate natural clusters. However, the had a small sample size from only two countries. Here, we investigated replicability of identifying clusters larger more diverse TOSCA study....
Background and purpose: The H63D polymorphism in the hemochromatosis ( HFE ) gene has been reported as a risk factor for amyotrophic lateral sclerosis (ALS) Europe America, but no data have Asia. Here, we investigated possible association between sporadic ALS (sALS) Chinese Han population. Methods: A total of 195 individuals with sALS from three centers China 405 unrelated healthy controls were recruited. All subjects genotyped by restriction fragment length (RFLP) analysis. Results:...
Objectives: Intracranial alveolar echinococcosis (IAE), a zoonotic disease, is critical health problem in the Tibetan region. We aimed to describe clinical and radiological characteristics outcomes among patients with IAE. Methods: screened diagnosed IAE between March 2015 May 2019 at Ganzi Autonomous Prefecture People's Hospital. Detailed demographics, characteristics, neuroimaging features, were recorded. Results: A total of 21 an average age 44.1 ± 12.7 years included. Thirteen (61.9%)...
Silicosis is a fibrosing and irreversible lung disease. In China, 9870 new silicosis cases were reported in 2010. The physical mental status of patients with should be paid attention to. aims this study to evaluate the influence patients' functional capacity on subjective well-being (SWB) quality life (QOL), provide scientific basis for further intervention measures, improve their health status.We investigated 324 inpatients during April 2011 September 2011. 6-minute walk test (6MWT) was...
Abstract Conventional brain magnetic resonance imaging (MRI) of anti-N-methyl-D-aspartate-receptor encephalitis (NMDARE) is non-specific, thus showing little differential diagnostic value, especially for MRI-negative patients. To characterize patterns structural alterations and facilitate the diagnosis NMDARE patients, we build two support vector machine models (NMDARE versus healthy controls [HC] model viral [VE] model) based on radiomics features extracted from MRI. A total 109 patients in...
The association between health-related quality of life (HRQOL) and ameliorable health impairment was examined in 208 Chinese in-patients with silicosis, April 2010. Median St George's Respiratory Questionnaire scores for symptom activity impairment, social support rating scale geriatric depression patients were 57.24, 59.45, 35 5, respectively. 36-item short-form survey physical component (PCS) mental (MCS) 47.17 51.05, Lower than median PCS (< 47) significantly associated high levels...
The aims are to assess respiration-related quality of life using the St. George Respiratory Questionnaire and determine its influencing factors among patients with silicosis in China.The incidence had an increasing trend recent years developing countries. Although majority therapy routinely, patients' has been impaired because cannot be cured. study on is few, clinical physicians have difficulty planning promote according current health situation.A cross-sectional design was used for this...
ObjectiveThis study aimed to summarize the clinical features of patients who presented intractable hiccup (IH) without brain and medulla oblongata (MO) lesions.MethodThis included six were diagnosed with inflammatory demyelinating myelitis, categorized as neuromyelitis optica (NMO), multiple sclerosis (MS), myelitis. Patients IH cervical lesions but MO also included. Clinical profiles, laboratory data, magnetic resonance imaging findings analyzed.ResultsThree out NMO, whereas remaining three...
Invasive intracranial aspergillosis in immunocompetent patients remains a rarity. We report such case male who developed symptoms after dental extraction. Attention should be paid to atypical central nervous system procedures; early diagnosis and management are of great importance improve outcomes.