A5076609646- Insect symbiosis and bacterial influences
- Insect-Plant Interactions and Control
- Chromosomal and Genetic Variations
- Plant Virus Research Studies
- Insect Resistance and Genetics
- Influenza Virus Research Studies
- Genomics and Phylogenetic Studies
- Animal Disease Management and Epidemiology
- Genomics and Chromatin Dynamics
- Crop Yield and Soil Fertility
- Entomopathogenic Microorganisms in Pest Control
- Plant Disease Resistance and Genetics
- Insect and Arachnid Ecology and Behavior
- CRISPR and Genetic Engineering
- Respiratory viral infections research
- Insect and Pesticide Research
- Viral gastroenteritis research and epidemiology
- Plant responses to water stress
- Insect Utilization and Effects
- Neurobiology and Insect Physiology Research
- Plant-Microbe Interactions and Immunity
- Genetic diversity and population structure
- Genomic variations and chromosomal abnormalities
- Nematode management and characterization studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
2023-2025
Institut de Génétique, Environnement et Protection des Plantes
2015-2024
Université de Rennes
2018-2024
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020-2024
Département Santé Animale
2024
CEA Paris-Saclay
2023
Virologie et Immunologie Moléculaires
2023
L'Institut Agro
2020-2022
Institut Agro Rennes-Angers
2018-2020
Max Planck Institute of Immunobiology and Epigenetics
2018-2020
The Galaxy HiCExplorer provides a web service at https://hicexplorer.usegalaxy.eu. It enables the integrative analysis of chromosome conformation by providing tools and computational resources to pre-process, analyse visualize Hi-C, Capture Hi-C (cHi-C) single-cell (scHi-C) data. Since last publication, has been expanded considerably with new facilitate cHi-C provide an in-depth Moreover, it supports scHi-C data offering broad range tools. With help standard graphical user interface Galaxy,...
Galaxy HiCExplorer is a web server that facilitates the study of 3D conformation chromatin by allowing Hi-C data processing, analysis and visualization. With server, users with little bioinformatic background can perform every step in one workflow: mapping raw sequence data, creation contact matrices, quality assessment, correction matrices identification topological associated domains (TADs) A/B compartments. Users create publication ready plots matrix, compartments, TADs on selected...
The combination of long reads and long-range information to produce genome assemblies is now accepted as a common standard. This strategy not only allows access the gene catalogue given species but also reveals architecture organization chromosomes, including complex regions such telomeres centromeres. Brassica genus exempt, many based on are available. reference for napus, Darmor-bzh, which was published in 2014, produced using short its contiguity extremely low compared with current genus....
The induction of alcohol fermentation in roots is a plant adaptive response to flooding stress and oxygen deprivation. Available transcriptomic data suggest that fermentation-related genes are also frequently induced infected with gall forming pathogens, but the biological significance this unclear. In study, we addressed role hypoxia responses Arabidopsis during infection by clubroot agent Plasmodiophora brassicae. hypoxia-related gene markers PYRUVATE DECARBOXYLASE 1 (PDC1), 2 (PDC2)...
Genome rearrangements that occur during evolution impose major challenges on regulatory mechanisms rely three-dimensional genome architecture. Here, we developed a scaffolding algorithm and generated chromosome-length assemblies from Hi-C data for studying topology in three distantly related Drosophila species. We observe extensive shuffling between these species with one synteny breakpoint after approximately every six genes. A/B compartments, set of large gene-dense topologically...
The rice weevil Sitophilus oryzae is one of the most important agricultural pests, causing extensive damage to cereal in fields and stored grains. S. has an intracellular symbiotic relationship (endosymbiosis) with Gram-negative bacterium Sodalis pierantonius a valuable model decipher host-symbiont molecular interactions.We sequenced genome using combination short long reads produce best assembly for Curculionidae species date. We show that undergone successive bursts transposable element...
Summary Meiotic recombination is a major evolutionary process generating genetic diversity at each generation in sexual organisms. However, this highly regulated, with the majority of crossovers lying distal chromosomal regions that harbor low DNA methylation levels. Even these regions, some islands without remain, for which we investigated underlying causes. Genetic maps were established two Brassica napus hybrids to detect presence such large nonrecombinant islands. The role played by and...
<title>Abstract</title> Background Swine influenza A viruses (swIAV) are highly contagious zoonotic pathogens that cause an acute respiratory infection in pigs, presenting substantial economic and health risks. This drives the pig industry stakeholders animal to monitor swIAV livestock. Prior 2009 flu pandemic, H1<sub>av</sub>N1 (HA-1C.2.1) H1<sub>hu</sub>N2 (HA-1B.1.2.3) circulated herds France. The H1N1<sub>pdm</sub> (HA-1A.2.3.3) lineage became enzootic after its introduction. In 2020, a...
Heterogametic species display a differential number of sex chromosomes resulting in imbalanced transcription levels for these between males and females. To correct this disequilibrium, dosage compensation mechanisms involving gene expression chromatin accessibility regulations have emerged throughout evolution. In insects, been extensively characterized only Drosophila but not insects agronomical importance. Aphids are indeed major pests wide range crops. Their remarkable ability to switch...
Abstract In 2020, a new genotype of swine H1N2 influenza virus (H1 av N2–HA 1C.2.4) was identified in France. It rapidly spread within the pig population and supplanted previously predominant H1 N1-HA 1C.2.1 virus. To characterize this which is genetically antigenically distant from other Nx viruses detected France, an experimental study conducted to compare outcomes N2 N1 infections pigs evaluate protection conferred by only inactivated vaccine currently licensed Europe containing HA 1C...
The identity and history of the indigenous groups who occupied Lesser Antilles during ceramic periods remain highly controversial. Although recent archaeological evidence has challenged hypotheses concerning organization human in this region, more biological data are needed to fully inform discussion. Our study provides, our knowledge, first palaeogenetic for Late Ceramic Guadeloupe archipelago, yielding crucial information identities these groups. Despite generally poor DNA preservation...
Ecology of insects is as wide their diversity, which reflects high capacity adaptation in most the environments our planet. Aphids, with over 4,000 species, have developed a series adaptations including phenotypic plasticity and ability to feed on phloem sap plants, enriched sugars derived from photosynthesis. Recent analyses aphid genomes indicated level shared ancestral gene duplications that might represent basis for genetic innovation broad adaptations. In addition, there are large...
Influenza D virus was isolated from pigs on a mixed pig and beef farm in France. Investigation suggested bull-to-pig transmission spread among pigs. The swine influenza recovered reassortant of D/660 D/OK lineages. Reported mutations the receptor binding site might be related to host adaptation.
Abstract Meiotic recombination is a key biological process in plant evolution and breeding, as it generates genetic diversity each generation through the formation of crossovers (COs). However, due to their importance genome stability, COs are highly regulated frequency distribution. We previously demonstrated that this strict regulation can be modified, both terms CO distribution, allotriploid Brassica hybrids (2n = 3x 29; AAC) resulting from cross between napus 4x 38; AACC) rapa 2x 20;...
Swine influenza A viruses (swIAVs) are a major cause of respiratory disease in pigs worldwide, presenting significant economic and health risks. These can reassort, creating new strains with varying pathogenicity cross-species transmissibility. This study aimed to monitor the genetic antigenic evolution swIAV France from 2019 2022. Molecular subtyping revealed marked increase H1avN2 cases 2020 onwards, altering previously stable subtypes' distribution. Whole-genome sequencing phylogenetic...
Abstract Background The combination of long-reads and long-range information to produce genome assemblies is now accepted as a common standard. This strategy not only allow access the gene catalogue given species but also reveals architecture organisation chromosomes, including complex regions like telomeres centromeres. Brassica genus exempt many based on long reads are available. reference for napus , Darmor-bzh, which was published in 2014, has been produced using short-reads its...
Clubroot, a disease of Brassicaceae species, is caused by the soilborne pathogen Plasmodiophora brassicae . High soil water content was previously described to favour motility zoospores and their penetration into root cells. In this study, effect irrigation regimes on clubroot development during post‐invasive secondary phase infection investigated. Three (low, standard, high) were tested two Arabidopsis accessions, Col‐0 (susceptible) Bur‐0, partially resistant line. Col‐0, symptoms resting...
Males and females share essentially the same genome but differ in their optimal values for many phenotypic traits, which can result intra-locus conflict between sexes. Aphids display XX/X0 sex chromosomes combine unusual X chromosome inheritance with cyclical parthenogenesis. Theoretical empirical works support hypothesis that large excess of male-biased genes observed on aphid compared to autosomes evolved response sexual conflicts, by restricting products sexually antagonistic alleles they...
Abstract Genome rearrangements that occur during evolution impose major challenges on regulatory mechanisms rely three-dimensional genome architecture. Here, we developed a scaffolding algorithm and generated chromosome-length assemblies from Hi-C data for studying topology in three distantly related Drosophila species. We observe extensive shuffling between these species with one synteny breakpoint after approximately every six genes. A/B compartments, set of large gene-dense topologically...
Whereas bovine has been demonstrated as the main reservoir of influenza D virus (IDV), this was first isolated in a pig and is regularly detected some swine populations. However, role IDV ecology, well outcomes infection pigs, still unclear. This study aimed to provide additional information on pathogenesis, transmission, adaptation bovine-origin swine. An transmission study, using an strain following passage IDV, conducted specific pathogen-free including inoculated direct contact pigs. Two...
Abstract Swine influenza A viruses (swIAV) are a major cause of respiratory disease in pigs worldwide, presenting significant economic and health risks. These can reassort, creating new strains with varying pathogenicity cross-species transmissibility. This study aimed to monitor the genetic antigenic evolution swIAV France from 2019 2022. Molecular subtyping revealed marked increase H1 av N2 cases 2020 onwards, altering previously stable subtypes’ distribution. Whole-genome sequencing...