A5069683470- Plant Molecular Biology Research
- Genomics and Phylogenetic Studies
- RNA Research and Splicing
- Cell Adhesion Molecules Research
- Structural Behavior of Reinforced Concrete
- Structural Load-Bearing Analysis
- Genetic Mapping and Diversity in Plants and Animals
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Plant Reproductive Biology
- RNA modifications and cancer
- Chromosomal and Genetic Variations
- Bacteriophages and microbial interactions
- RNA and protein synthesis mechanisms
- Seismic Performance and Analysis
- Transgenic Plants and Applications
- Ocean Acidification Effects and Responses
- Plant Stress Responses and Tolerance
- Structural Engineering and Materials Analysis
- Plant tissue culture and regeneration
- Extracellular vesicles in disease
- Neuroscience and Neural Engineering
- Plant Genetic and Mutation Studies
- Vibrio bacteria research studies
- Tendon Structure and Treatment
Southeast University
2023-2024
National Health and Family Planning Commission
2024
Peking University
2022-2024
East Carolina University
2021-2024
Beijing Normal University
2024
Chongqing University
2024
Peking University First Hospital
2022
Sichuan Agricultural University
2018-2022
Institute of Crop Sciences
2016-2018
Chinese Academy of Agricultural Sciences
2008-2018
The Pacific oyster Crassostrea gigas belongs to one of the most species-rich but genomically poorly explored phyla, Mollusca. Here we report sequencing and assembly genome using short reads a fosmid-pooling strategy, along with transcriptomes development stress response proteome shell. is highly polymorphic rich in repetitive sequences, some transposable elements still actively shaping variation. Transcriptome studies reveal an extensive set genes responding environmental stress. expansion...
Abstract Flowers are produced by floral meristems, groups of stem cells that give rise to organs. In grasses, including the major cereal crops, flowers (florets) contained in spikelets, which contain one many florets, depending on species. Importantly, not all grass florets developmentally equivalent, and or more often sterile abort each spikelet. Members Andropogoneae tribe, maize (Zea mays), produce spikelets with two florets; upper lower usually dimorphic, floret is greatly reduced...
Abstract Eukaryotic Argonaute proteins play primary roles in miRNA and siRNA pathways that are essential for numerous developmental biological processes. However, the functional of four ZmAGO1 genes have not yet been characterized maize ( Zea mays L.). In present study, ZmAGO1a was identified from putative further characterization. Complementation Arabidopsis ago1‐27 mutant with indicated constitutive overexpression could restore smaller rosette, serrated leaves, later flowering maturation,...
Implantable bioelectronics hold tremendous potential in the field of healthcare, yet performance these systems heavily relies on interfaces between artificial machines and living tissues. In this paper, we discuss recent developments tethered interfaces, as well those non-tethered interfaces. Among them, that study neural activity receive significant attention due to their innovative high relevance contemporary research, but other functional types interface are also explored provide a...
The reinforced part at the bottom of high-rise assembled monolithic concrete shear wall structures generally uses cast-in-place due to high elastic–plastic deformation capacity requirements, which limits advantages prefabricated structures. This study investigates feasibility using cluster connections assemble integral by modifying vertical reinforcement connection. Numerical simulations ABAQUS (Version 2019) were validated with laboratory test results. seismic performance walls was examined...
As a well-known cancer-related miRNA, miR-193b-3p is enriched in skeletal muscle and dysregulated disease. However, the mechanism underpinning this has not been addressed so far. Here, we probed impact of on myogenesis by mainly using goat tissues satellite cells (MuSCs), compared with mouse C2C12 myoblasts. highly expressed muscles, ectopic promotes MuSCs proliferation differentiation. Moreover, insulin-like growth factor-2 mRNA-binding protein 1 (IGF2BP1) most activated insulin signaling...
Phylogenetic trees based on genome-wide single nucleotide polymorphisms (SNPs) among diverse inbreds could provide valuable and intuitive information for breeding germplasm management in crops. As a result of sequencing technology developments, huge amount whole genome SNP data have become available affordable breeders. However, it is challenge to perform quick reliable plotting the data. To meet this goal, visualization pipeline was developed demonstrated publicly from current important...
Tumor diagnosis, especially at the early stages, holds immense significance. Focal adhesion kinase (FAK) is often highly expressed across various types of tumors, making it a promising target for both therapy and diagnosis. In this study, seven novel inhibitors were designed synthesized. The inhibitory activity these compounds against FAK was notably potent, with an IC50 range 1.27–1968 nM. particular, 7a 7c, values 5.59 nM 1.27 nM, respectively, radiolabeled F-18 then evaluated S-180...
SUMMARY MicroRNAs are short, non‐coding RNAs that repress gene expression in both plants and animals have diverse functions related to growth, development, stress responses. The ribonuclease, DICER‐LIKE1 (DCL1) is required for two steps plant miRNA biogenesis: cleavage of the primary miRNAs (pri‐miRNAs) release a hairpin structure, called precursor (pre‐miRNA) pre‐miRNA generate miRNA/miRNA* duplex. mature guides RNA‐induced silencing complex target with complementary sequences, resulting...
In recent years, Large Language Models (LLMs) have demonstrated remarkable capabilities across diverse NLP tasks. Extensive research has explored how to enhance the logical reasoning abilities such as Chain-of-Thought, Chain-of-Thought with Self-Consistency, Tree-Of-Thoughts, and multi-agent debates. context of debates, significant performance improvements can be achieved an increasing number agents debate rounds. However, escalation in rounds drastically raise tokens cost thereby limiting...
In order to investigate the seismic performance of a precast shear wall with new bundled connection under high axial compressive ratio, three full-scale short-limb walls and one cast-in-place were manufactured loaded cycling loading. The results show that has similar damage mode crack evolution wall. Under same compression bearing capacity, ductility coefficient, stiffness, energy dissipation capacity better, its is related increase ratio. embedded bellows can limit cracking but have little...
Abstract Flowers are produced by floral meristems, groups of stem cells that give rise to organs. In grasses, including the major cereal crops, flowers (florets) contained in spikelets, which contain one many florets, depending on species. Importantly, not all grass florets developmentally equivalent, and or more often sterile abort each spikelet. Members Andropogoneae tribe, maize, produce spikelets with two florets; upper lower usually dimorphic floret greatly reduced compared floret....
Abstract BackgroundAs a well-known cancer-related miRNA, miR-193b-3p is enriched in skeletal muscle but dysregulated disease. However, mechanism underpinning has not been addressed so far. MethodsHere, we probed the impact of on myogenesis by mainly using goat tissues and satellite cells (MuSCs), with combined methods including RNA-seq to profile transcriptome affected miR-193b-3p, cell-counting kit-8 (CCK-8) 5-ethynyl-2'-deoxyuridine (EdU) for cell proliferation assay, RNA-RNA dual-labeled...