A5113180070- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Reproductive System and Pregnancy
- Electric and Hybrid Vehicle Technologies
- Ovarian function and disorders
- Renal and related cancers
- Reproductive Health and Technologies
- Urologic and reproductive health conditions
- Uterine Myomas and Treatments
- Testicular diseases and treatments
- Reproductive biology and impacts on aquatic species
- Climate Change and Health Impacts
- Advanced Battery Technologies Research
- Prenatal Screening and Diagnostics
- Microtubule and mitosis dynamics
- Advanced Combustion Engine Technologies
- Sexual Differentiation and Disorders
- Reproductive tract infections research
- Gynecological conditions and treatments
- Reconstructive Surgery and Microvascular Techniques
- Genetic and Kidney Cyst Diseases
- Air Quality and Health Impacts
- Genetic and rare skin diseases.
- Advancements in Battery Materials
- Refrigeration and Air Conditioning Technologies
University of Science and Technology of China
2018-2024
Chongqing University of Technology
2024
Government College University, Lahore
2022
Putian University
2019
Anhui Provincial Hospital
2018
Multiple morphological abnormalities of the sperm flagella (MMAF) are most severe form asthenozoospermia due to impaired axoneme structure in flagella. Dynein arms necessary components flagellar axoneme. In this study, we recruited 3 unrelated consanguineous Pakistani families with multiple MMAF-affected individuals, who had no overt ciliary symptoms. Whole-exome sequencing and Sanger identified 2 cilia associated protein 57 (CFAP57) loss-of-function mutations (c.2872C>T, p. R958*;...
Intrauterine adhesions (IUA) are associated with the loss of stem cells in endometrium. Menstrual blood‑derived (MenSCs) can be isolated from menstrual blood and differentiated into endometrial cells. To check transplantation feasibility MenSCs for treatment severe IUA, were blood, cultured Dulbecco's modified Eagle's medium (DMEM), identified by immunocytochemistry flow cytometry, vitro, finally transplanted axillary subcutaneous tissue non‑obese diabetic/severe combined immunodeficiency...
Asthenoteratozoospermia is one of the most severe types qualitative sperm defects. Most cases are due to mutations in genes encoding components flagella, which have an ultrastructure similar that motile cilia. Coiled-coil domain containing 103 ( CCDC103 ) outer dynein arm assembly factor, and pathogenic variants cause primary ciliary dyskinesia (PCD). However, whether asthenoteratozoospermia has yet be determined. Whole-exome sequencing (WES) was performed for two individuals with...
To investigate the effect of weight loss on pregnancy outcomes, PCOS related neuronal-reproductive-metabolic hormones and ovarian granulosa cell gene expression profiles in obese infertile patients undergoing vitro fertilization-embryo transfer (IVF-ET). 75 IVF-ET due to tubal factors alone collected as control group (group A), 352 with infertility were divided into four groups according amount before IVF: 0 kg B), 1-5 C), 5-10 D), >10 E). Six cases cells randomly random number table method...
Azoospermia is a significant cause of male infertility, with non-obstructive azoospermia (NOA) being the most severe type spermatogenic failure. NOA mostly caused by congenital factors, but our understanding its genetic causes very limited. Here, we identified frameshift variant (c.201_202insAC, p.Tyr68Thrfs∗17) and two nonsense variants (c.1897C>T, p.Gln633∗; c.2005C>T, p.Gln669∗) in KCTD19 (potassium channel tetramerization domain containing 19) from unrelated infertile Chinese men...
Acephalic spermatozoa syndrome is a rare type of teratozoospermia causing male infertility due to detachment the sperm head and flagellum, which precludes fertilization potential. Although loss-of-function variations in several genes, including TSGA10, have been associated with acephalic syndrome, genetic cause many cases remains unclear. We recruited Pakistani family two infertile brothers who suffered from syndrome. Through whole-exome sequencing (WES) followed by Sanger sequencing, we...
Human autologous sperm freezing involves ejaculated sperm, and testicular or epididymal puncture freezing, is widely used in assisted reproductive technology. In previous studies, researchers have tried to cryopreserve from mammals (rats, dogs, etc.) using a -80°C freezer achieved success. It common use liquid nitrogen vapor rapid human sperm. However, the operation of this cooling method complicated, temperature drop unstable. study, we compared quality ejaculation after for first time. By...
Ureaplasma urealyticum (UU) is one of the most commonly occurring pathogens associated with genital tract infections in infertile males, but impact seminal UU infection semen on intrauterine insemination (IUI) outcomes poorly understood. We collected data from 245 couples who underwent IUI at The First Affiliated Hospital USTC (Hefei, China) between January 2021 and 2023. subjects were classified into two groups according to their status: UU-positive group UU-negative group. compared...
Abstract Background With the development of socio‐economic conditions and a shift in attitudes towards fertility, there has been gradual increase delayed childbearing since 2000s. Age plays significant role decline fertility. However, we know very little about association paternal age with reproductive outcomes. Objectives To investigate correlation between advanced semen quality, embryo pregnancy, neonatal outcomes IVF cycles. Materials methods In this study, after excluding female partners...
The control strategy of the thermal management system is crucial for ensuring comfort an electric vehicles (EVs) cabin. However, performance heat pump air conditioning (HPAC) significantly deteriorates in low‐temperature weather conditions. In recent years, CO 2 HPAC has emerged as a potential solution to address insufficient heating capacity such environments. order ensure cabin and optimize winter mileage, three‐stage method source (ASHP) proposed this article. Firstly, simulation model...
To introduce a contralateral mastoplasty in breast reconstruction with prosthesis after cancer surgery order to gain bilateral breasts symmetry.Between January 2016 and June 2018, 11 female patients were treated, aged 34-64 years old (mean, 49.6 years). There 5 cases left side 6 right side. 3 of invasive carcinoma 8 intraductal carcinoma. The diameter tumor was 0.2-4.1 cm 2.5 cm). disease duration ranged from 1 15 months months). According Regnault grading criteria, there 7 mild ptosis 4...
Currently, the cryopreservation of human spermatozoa must overcome adverse effects excessive oxidation. In this study, we aimed to evaluate effect supplementation medium with cyanidin-3-Ο-glucoside (C3G) on sperm quality. Semen samples were obtained from men normozoospermia according WHO criteria (n = 39). The parameter values compared after in supplemented and without C3G.Compared control group (without additive), low doses (50 μM 100 μM) C3G improved viability motility decreased reactive...