A5100768802- Cancer-related molecular mechanisms research
- CRISPR and Genetic Engineering
- Circular RNAs in diseases
- Cancer Immunotherapy and Biomarkers
- MicroRNA in disease regulation
- Family and Disability Support Research
- Cerebrovascular and Carotid Artery Diseases
- Solar-Powered Water Purification Methods
- Solar Thermal and Photovoltaic Systems
- Immunotherapy and Immune Responses
- Chemokine receptors and signaling
- Soybean genetics and cultivation
- Hippo pathway signaling and YAP/TAZ
- Gut microbiota and health
- Inflammatory Biomarkers in Disease Prognosis
- Atherosclerosis and Cardiovascular Diseases
- Protease and Inhibitor Mechanisms
- Cell Adhesion Molecules Research
- Venous Thromboembolism Diagnosis and Management
- Adolescent and Pediatric Healthcare
- Acupuncture Treatment Research Studies
- Tryptophan and brain disorders
- Resilience and Mental Health
- MRI in cancer diagnosis
- Genetic Mapping and Diversity in Plants and Animals
Nanjing Agricultural University
2024-2025
Nanjing Chest Hospital
2024
Nanjing Medical University
2024
Nanjing Brain Hospital
2024
Shanxi Medical University
2015-2024
Jiangsu Academy of Agricultural Sciences
2024
China Medical University
2016-2024
Wuhan University of Science and Technology
2022-2024
China Agricultural University
2023-2024
Qingdao Agricultural University
2024
Abstract Inflammatory depression is a treatment-resistant subtype of depression. A causal role the gut microbiota as source low-grade inflammation remains unclear. Here, part an observational trial, we first analyze composition in stool, inflammatory factors and short-chain fatty acids (SCFAs) plasma, permeability markers intestinal mucosa patients with (ChiCTR1900025175). Gut exhibits higher Bacteroides lower Clostridium , increase SCFA-producing species abnormal butanoate metabolism. We...
Atherosclerosis-associated cardiovascular disease is one of the main causes death and disability among patients with diabetes mellitus. However, little known about impact S-nitrosylation in diabetes-accelerated atherosclerosis. Here, we show increased levels guanine nucleotide-binding protein G(i) subunit alpha-2 (SNO-GNAI2) at Cysteine 66 coronary artery samples from diabetic atherosclerosis, consistently results mice. Mechanistically, SNO-GNAI2 acted by coupling CXCR5 to dephosphorylate...
Soybean [ Glycine max (L.)Merr.] is a leading oil-bearing crop and cultivated globally over vast scale. The agricultural landscape in China faces formidable challenge with drought significantly impacting soybean production. In this study, we treated natural population of 264 Chinese accessions using 15% PEG-6000 used GR, GE, GI, RGR, RGE, RGI ASFV as evaluation index. Using the ASFV, screened 17 strong drought-tolerant germplasm germination stage. Leveraging 2,597,425 high-density SNP...
The aim of this study was to detect FOXC1 expression in human non-small cell lung cancer (NSCLC) and analyze its association with prognosis NSCLC patients. Expressional levels mRNA protein 30 cases corresponding non-tumor tissue samples were examined by quantitative real-time PCR Western blotting. Immunohistochemistry performed the 125 tissues. We found that tissues significantly higher than those High-level correlated poor tumor differentiation, tumor-node-metastasis stage, lymph node...
Salt stress poses a significant challenge to crop productivity, and understanding the genetic basis of salt tolerance is paramount for breeding resilient soybean varieties. In this study, natural population was evaluated during germination stage, focusing on key traits, including rate (GR), energy (GE), index (GI). It seen that under stress, obvious inhibitions were found these with GR, GE, GI diminishing by 32% 54% when compared normal conditions. These traits displayed coefficient...
InfoMetricsFiguresRef. Journal of Agricultural and Food ChemistryASAPArticle This publication is free to access through this site. Learn More CiteCitationCitation abstractCitation referencesMore citation options ShareShare onFacebookXWeChatLinkedInRedditEmailBlueskyJump toExpandCollapse ViewpointMarch 20, 2025An Insect-Proof Net Technique Can Help Reduce Pesticide Application on VegetablesClick copy article linkArticle link copied!Junyan WangJunyan WangState Key Laboratory Forestry...
Family function is important for the normal operation of family and development children. However, existing studies have limited explorations on among families patients with cleft lip and/or palate (CL/P). This study aims to validate a hypothesized model based adjustment adaptation response model, identify key variables affecting (CL/P) in China. The cross-sectional enrolled 248 CL/P from two centers demographic, clinical, function, resilience, hope, perceived social support, optimism,...
In forensic science, accurate estimation of the age a victim or suspect can facilitate investigators to narrow search and aid in solving crime. Aging is complex process associated with various molecular regulations on DNA RNA levels. Recent studies have shown that circular RNAs (circRNAs) upregulate globally during aging multiple organisms such as mice C.elegans because their ability resist degradation by exoribonucleases. current study, we attempted investigate circRNAs' potential...
Abstract Fibroblast growth factor 18 (FGF18) emerges as a promising therapeutic target for osteoarthritis (OA). In this study, novel articular cavity‐localized lipid nanoparticle (LNP) named WG‐PL14 is developed. This optimized formulation has nearly 30‐fold increase in mRNA expression well better cavity enrichment compared to commercial lipids MC3 when performing intra‐articular injection. Then, sequence encoding recombinant human FGF18 (rhFGF18) potential therapy OA optimized. vitro assays...
Background: Resilience has become a hot spot in the field of positive psychology to study life-change events. However, there were little information on resilience among fathers and mothers patients with cleft lip and/or palate respectively. The present aimed explore compare level potential influential factors associated fathers/mothers China. Method: A cross-sectional was carried out between April 2019 July 2020 two treatment centers Sixty Nine 179 interviewed questionnaire demographic...
Effective conservation and utilization of farm animals are fundamental for realizing sustainable increases in food production. In situ ex the two main strategies that currently used to protect genetic integrity Chinese domestic chicken breeds. However, genomic diversity population structure have not been compared these conserved populations.Three hundred sixty-one individuals from three breeds were collected populations genotyped using genotyping-by-sequencing (GBS). First, we different...
The fall armyworm (FAW) is a serious agricultural pest and has developed resistance to multiple insecticides. It necessary introduce novel insecticide(s) for controlling FAW. Isocycloseram completely isoxazoline insecticide. However, its activity mode of action against FAW have not been reported. In this study, isocycloseram exhibited higher insecticidal (LC
The aim of this study was to detect stress-induced phosphoprotein 1 (STIP1) expression in papillary thyroid carcinoma (PTC) and analyze its association with prognosis PTC patients. Immunohistochemistry performed the STIP1 113 tissues paired adjacent noncancerous tissues. χ2 test used relationship between clinicopathological characteristics. Survival curves were plotted by Kaplan-Meier method compared using log-rank test. data evaluated univariate multivariate Cox regression analysis. We...
Aging is a complicated process characterized by progressive and extensive changes in physiological homeostasis at the organismal, tissue, cellular levels. In modern society, age estimation essential large variety of legal rights duties. Accumulating evidence suggests roles for microRNAs (miRNAs) circular RNAs (circRNAs) regulating numerous processes during aging. Here, we performed circRNA sequencing two groups analyzed microarray data 171 healthy subjects (17-104 years old) downloaded from...
Impact of bone mesenchymal stem cell (BMSC) transfusion on chronic smoking-induced lung inflammation is poorly understood. In this study, a rat model smoking-related injury was induced and the rats were treated with vehicle or BMSCs for two weeks. Different subsets CD4+ T cells, cytokines, anti-elastin in lungs as well characterized. Serum inducible nitric oxide synthase (iNOS) STAT5 phosphorylation lymphocytes from tissue also analyzed. Results indicated that significantly reduced injury,...
The activation of coagulation and fibrinolysis is frequently encountered among cancer patients. Such tumors are associated with high risk invasion, metastases, negative final outcomes. Non-small cell lung (NSCLC) accounts for approximately 80% to 85% all malignancies. This study aims investigate the prognostic value blood tests NSCLC provide a reference patients on prevention treatment thrombophilia.Data were collected from 604 cases hospitalized histologically confirmed January 2009...