Zhishang Li

ORCID: 0009-0007-6651-8573
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About
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Research Areas
  • Sepsis Diagnosis and Treatment
  • Immune Cell Function and Interaction
  • Reproductive System and Pregnancy
  • Hematopoietic Stem Cell Transplantation
  • Traditional Chinese Medicine Analysis
  • Traditional Chinese Medicine Studies
  • Pharmacological Effects of Natural Compounds
  • Plant-based Medicinal Research
  • Respiratory Support and Mechanisms
  • Ultrasound and Cavitation Phenomena
  • Galectins and Cancer Biology
  • Microfluidic and Bio-sensing Technologies
  • Acute Myocardial Infarction Research
  • Venomous Animal Envenomation and Studies
  • Cancer-related molecular mechanisms research
  • Macrophage Migration Inhibitory Factor
  • Circular RNAs in diseases
  • Metabolomics and Mass Spectrometry Studies
  • Extracellular vesicles in disease
  • Soft tissue tumor case studies
  • Pickering emulsions and particle stabilization
  • Kawasaki Disease and Coronary Complications
  • Atherosclerosis and Cardiovascular Diseases
  • Rabies epidemiology and control
  • Gastrointestinal disorders and treatments

Guangdong Provincial Hospital of Traditional Chinese Medicine
2022-2024

Guangzhou University of Chinese Medicine
2019-2024

Guangdong Provincial People's Hospital
2023-2024

Center for High Pressure Science & Technology Advanced Research
2022-2024

Guangdong Academy of Medical Sciences
2023-2024

Zhejiang University
2021

Zigong First People's Hospital
2021

Sichuan University
2021

Duke University
2019

Tianjin Medical University
2011-2014

Synthesis of nanoparticles and particulate nanomaterials with tailored properties is a central step toward many applications ranging from energy conversion imaging/display to biosensing nanomedicine. While existing microfluidics-based synthesis methods offer precise control over the process, most them rely on passive, partial mixing reagents, which limits their applicability potentially, adversely alter synthesized products. Here, an acoustofluidic (i.e., fusion acoustic microfluidics)...

10.1002/advs.201900913 article EN cc-by Advanced Science 2019-08-27

Abstract Exosomes are cell-derived nanovesicles that have recently gained popularity as potential biomarkers in liquid biopsies due to the large amounts of molecular cargo they carry, such nucleic acids and proteins. However, most existing exosome-based analytical sensing methods struggle achieve high sensitivity selectivity simultaneously. In this work, we present an electrochemical micro-aptasensor for highly sensitive detection exosomes by integrating a micropatterned aptasensor...

10.1038/s41378-021-00293-8 article EN cc-by Microsystems & Nanoengineering 2021-08-17

Severe aplastic anemia (SAA) is a rare disease characterized by severe pancytopenia and bone marrow failure. Natural killer (NK) cells are large granular lymphocytes derived from hematopoietic stem (HSCs) or common lymphoid progenitors (CLP). They play key role in n the innate immunity adaptive immune. In this study, quantitative functional changes of natural cell subsets peripheral blood patients before after immunosuppressive therapy (IST) were investigated. Results showed that percentage...

10.3109/08820139.2014.888448 article EN Immunological Investigations 2014-03-24

Background: Nonalcoholic fatty liver disease (NAFLD) is the most common metabolic and intertwined with cardiovascular disorders diabetes. Chaihu Shugan powder (CSP) a traditional Chinese medicine significant therapeutic effect on diseases, such as NAFLD. However, its pharmacological mechanisms remain to be elucidated. Methods: The main compounds of CSP were measured using LC-MS/MS. A network pharmacology study was conducted CSP. Its potential active ingredients selected according oral...

10.3389/fphar.2022.967623 article EN cc-by Frontiers in Pharmacology 2022-09-12

In article number 1900913, Tony Jun Huang and co-workers utilize an acoustic-vortex-based active mixing strategy to demonstrate acoustic-based platform capable of synthesizing particulate nanomaterials in a controllable reproducible manner. This allows dynamic independent dictation the process simply by adjusting strength acoustic vortex. Using platform, synthesis is demonstrated such as polymeric nanoparticles, chitosan organic–inorganic hybrid nanomaterials, metal–organic frameworks...

10.1002/advs.201970113 article EN Advanced Science 2019-10-01

CONTEXT: Scrub typhus, caused by Orientia tsutsugamushi, has a wide range of clinical manifestations, including meningoencephalitis, acute renal failure, pneumonitis, myocarditis, and septic shock. However, there are no documented cases scrub typhus with hypokalemia. In this report, we present case hypokalemia multiple organ failure syndrome, highlighting the importance electrolyte imbalance in patients typhus. CASE REPORT: A 59-year-old woman presented to emergency department abdominal pain...

10.1590/1516-3180.2023.0142.r1.08122023 article EN cc-by Sao Paulo Medical Journal 2024-01-01

AbstractAim: To explore the effects of BOPPPS combined with RCDP theory in Basic life support training for new nurses.Background: is an essential skill that every nurse must master, especially nurses. However, relying on traditional methods, such as classroom instruction and simulation exercises, may not provide enough practical experience or feedback accurately reflects real-life scenarios. That's why there a pressing need innovative strategies to help nurses enhance their proficiency basic...

10.2139/ssrn.4816799 preprint EN 2024-01-01

The effect of combining prone ventilation with traditional Chinese medicine on severe pneumonia remains unclear.

10.3389/fphar.2024.1428817 article EN cc-by Frontiers in Pharmacology 2024-07-24

Aims: The progressive development of myocardial remodeling following infarction (MI) ultimately leads to heart failure (HF). Inflammation has emerged as a crucial catalyst in cardiac remodeling, and inhibiting inflammatory factors holds promise for improved prognosis. In this study, we elucidate the role IFI-16 (Interferon Gamma Inducible Protein-16) inducing inflammation through inflammasome interacts with galectin-3 signaling pathway post-MI heart.Methods Results: Through analysis RNA...

10.2139/ssrn.4598963 preprint EN 2023-01-01

Abstract Background Septic shock is an important problem in critical care medicine and one of the leading causes death intensive units (ICU). In China, Traditional Chinese ( TCM) has been widely used as adjuvant treatment to improve symptoms prognosis patients with septic shock. Yiqi Fumai Injection (YFI) most proprietary TCM for shock, previous studies have demonstrated its efficacy safety. However, these conclusions were limited due small sample size low quality methodologies studies....

10.21203/rs.2.21820/v1 preprint EN cc-by Research Square (Research Square) 2020-01-24
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