A5101902391- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Health and Disease Prevention
- Venous Thromboembolism Diagnosis and Management
- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Inflammatory Biomarkers in Disease Prognosis
- Cerebrovascular and Carotid Artery Diseases
- Cardiomyopathy and Myosin Studies
- Heart Rate Variability and Autonomic Control
- Coronary Interventions and Diagnostics
- Protease and Inhibitor Mechanisms
- Cardiac Valve Diseases and Treatments
- Blood Pressure and Hypertension Studies
- Machine Learning in Healthcare
- Congenital heart defects research
- Cardiac Ischemia and Reperfusion
- Cardiac Health and Mental Health
- Viral Infections and Immunology Research
- Cardiovascular Disease and Adiposity
- Tissue Engineering and Regenerative Medicine
- S100 Proteins and Annexins
- Cardiovascular Health and Risk Factors
People's Hospital of Xinjiang Uygur Autonomous Region
2021-2024
Weatherford College
2023
First Affiliated Hospital of Xinjiang Medical University
2010-2022
Xinjiang Medical University
2010-2022
National Institute on Drug Abuse
2009
Shift work is associated with increased risk of acute myocardial infarction (AMI) and worsened prognosis. However, the mechanisms linking shift prognosis in AMI remain unclear. This study sought to investigate impact on reperfusion injury, a major determinant clinical outcomes AMI. Study patient data were obtained from database EARLY-MYO-CMR (Early Assessment Myocardial Tissue Characteristics by CMR STEMI) registry, which was prospective, multicenter registry patients ST-segment elevation...
Background Left atrial (LA) dysfunction is associated with morbidity and mortality. To the knowledge of authors, relationship LA strain to long-term prognosis in participants ST-segment elevation myocardial infarction (STEMI) unknown. Purpose evaluate as a outcome predictor STEMI prospective, multicenter cardiac MRI cohort. Materials Methods Participants who underwent primary percutaneous coronary intervention from 10 sites (EARLY-MYO-CMR registry, clinical trial number NCT03768453) were...
Abstract Aims A number of studies have attempted to demonstrate the benefits associated with personalized antiplatelet therapy guided by platelet function testing, which has led disappointing findings. In this study, we used a new test guide in stable coronary artery disease (CAD) patients after percutaneous intervention (PCI). Methods and results present randomized controlled trial, total 2237 CAD undergoing PCI were randomly chosen be administered (personalized group; n = 1123) or standard...
Abstract Objective Diabetes mellitus is a global epidemic disease. Long-time exposure of patients to hyperglycemia can lead various type chronic tissue damage. Early diagnosis and screening for diabetes are crucial population health. Methods We collected the national physical examination data in Xinjiang, China, 2020 (a total more than 4 million people). Three types indices were analyzed: questionnaire, routine laboratory values. Integrated learning, deep learning logistic regression methods...
Diabetic patients are prone to acute myocardial infarction. Although reperfusion therapy can preserve the viability of myocardium, it also causes fatal ischemia‒reperfusion injury. Diabetes exacerbate injury, but mechanism is unclear. We aimed characterize effects liraglutide on prevention injury and inadequate autophagy. Liraglutide reduced infarction area improved cardiac function in diabetic mice. further demonstrated that mediated these protective by activating AMPK/mTOR-mediated...
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) participates in the occurrence and development of cardiovascular cerebrovascular diseases such as stroke coronary heart disease by regulating inflammatory reactions, programmed cell death, other pathological processes. Previous studies revealed that MALAT1 gene polymorphism was associated with cardiac diseases. However, prognostic role major adverse events (MACCEs) remains unknown. Therefore, this study intends to explore...
Background: The impact of concomitant impairments left and right ventricular (LV RV) strain on the long-term prognosis acute ST-elevation myocardial infarction (STEMI) is not clear. Methods: We analyzed CMR images followed up 420 first STEMI patients from EARLY Assessment MYOcardial Tissue Characteristics by in (EARLY-MYO-CMR) registry (NCT03768453). These received timely primary percutaneous coronary intervention (PCI) within 12 h examination 1 week (median, 5 days; range, 2–7 days) after...
The number of patients undergoing percutaneous coronary intervention (PCI) procedures is increasing along with the studies involving guidelines, prognostic assessments, and cardiac rehabilitation related to PCI strategies. However, fewer have reported mapping knowledge structure hotspot analysis in this field. Our goal was discuss analyze current status, hot spots developmental trends associated research into prognosis PCI, provide reference for PCI-related research.
<title>Abstract</title> Dual antiplatelet therapy (DAPT) combined of aspirin and P2Y12 receptor inhibitors is the mainstay treatment after acute coronary syndrome (ACS), but there are some problems remained to be explored, such as duration DAPT choice inhibitors. This protocol evaluate clinical benefit pharmacogenomics (PGx)-based strategy for ACS patients through a real-world study. A total 6037 expected included in study, with 3185 assigned PGx group standard group. The primary endpoint...
Abstract Background: The available evidence regarding the benefits of percutaneous coronary intervention (PCI) on patients receiving dialysis with artery disease (CAD) is limited and inconsistent. This study aimed to evaluate association between PCI clinical outcomes as compared medical therapy alone in undergoing CAD China. Methods: multicenter, retrospective was conducted 30 tertiary centers across 12 provinces China from January 2015 June 2021 include CAD. primary outcome major adverse...
Explore the factors affecting QO of life after transcatheter aortic valve replacement (TAVR) and analyze evaluate their surgical efficacy postoperative survival status.