Laura S. Daedelow
A5023331633- Substance Abuse Treatment and Outcomes
- Functional Brain Connectivity Studies
- Attention Deficit Hyperactivity Disorder
- Schizophrenia research and treatment
- Child and Adolescent Psychosocial and Emotional Development
- Stress Responses and Cortisol
- Cannabis and Cannabinoid Research
- Bipolar Disorder and Treatment
- Advanced Neuroimaging Techniques and Applications
- Mental Health Research Topics
- Cognitive Abilities and Testing
- Prenatal Substance Exposure Effects
- Neural dynamics and brain function
- Neurotransmitter Receptor Influence on Behavior
- Infections and bacterial resistance
- Enhanced Oil Recovery Techniques
- Memory and Neural Mechanisms
- Face Recognition and Perception
- Treatment of Major Depression
- Animal testing and alternatives
- Medical and Health Sciences Research
- Bullying, Victimization, and Aggression
- Gambling Behavior and Treatments
- Tryptophan and brain disorders
- Birth, Development, and Health
Charité - Universitätsmedizin Berlin
2017-2024
Freie Universität Berlin
2018-2024
Humboldt-Universität zu Berlin
2018-2024
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2021
University Medical Center
2018
Centro de Investigacion Principe Felipe
2010
Universitat de València
2010
The orbitofrontal cortex (OFC) is implicated in depression. hypothesis investigated was whether the OFC sensitivity to reward and nonreward related severity of depressive symptoms. Activations monetary incentive delay task were measured IMAGEN cohort at ages 14 years (n = 1877) 19 1140) with a longitudinal design. Clinically relevant subgroups compared (high-severity group: n 116; low-severity 206) 14. medial exhibited graded activation increases reward, lateral had nonreward. In this...
Abstract Traditional models of future alcohol use in adolescents have used variable-centered approaches, predicting from a set variables across entire samples or populations. Following the proposition that predictive factors may vary as function family history, we two-pronged approach by first defining clusters familial risk, followed prediction analyses within each cluster. Thus, for time adolescents, tested whether with history drug abuse exhibit predictors different without history. We...
Ochrobactrum anthropi is a gram-negative bacillus recognized as human opportunist pathogen isolated in clinical specimens and not of significance. We report new aspect this bacterium, that it has been from activated sludge. In fact, able to grow on atrazine (2-chloro-4-ethylamino-6-isopropyl-amine-s-triazine) by utilizing the only source carbon. Our results show (0.03 g/liter) causes dramatical increase degree saturation membrane fatty acids. Analysis identification bacterial acids were...
Abstract Rationale For decades, cannabis has been the most widely used illicit substance in world, particularly among youth. Research suggests that mental health problems associated with use may result from its effect on reward brain circuit, emotional processes, and cognition. However, findings are mostly derived correlational studies inconsistent, adolescents. Objectives Methods Using data IMAGEN study, participants (non-users, persistent users, abstinent users) were classified according...
Importance The development of an alcohol use disorder in adolescence is associated with increased risk future dependence. differential associations factors over the course 8 years are important for preventive measures. Objective To determine risk-taking aspects personality, social factors, brain functioning, and familial hazardous adolescents years. Design, Setting, Participants IMAGEN multicenter longitudinal cohort study included recruited from European schools Germany, UK, France, Ireland...
Abstract Extensive research has demonstrated that rs1360780, a common single nucleotide polymorphism within the FKBP5 gene, interacts with early‐life stress in predicting psychopathology. Previous results suggest carriers of TT genotype rs1360780 who were exposed to child abuse show differences structure and functional activation emotion‐processing brain areas belonging salience network. Extending these findings on intermediate phenotypes psychopathology, we examined if interaction between...
Zusammenfassung. Komputationale Methoden werden in einem weiten Bereich psychiatrischer Forschung eingesetzt v.a. beim Umgang mit großen Datensätzen. Hier diskutieren wir, wie Hilfe komputationaler das Entscheidungsverhalten bestimmten Testsituationen mathematischen Gleichungen abgebildet kann, um diesem wiederum neurobiologischen Korrelaten zuordnen zu können. Ein bekanntes Beispiel ist belohnungsabhängige Lernen, bei dem die Größe eines Vorhersagefehlers, d.h. des Unterschieds zwischen der...
What effect does social exclusion have on the perception of other person and how can this be recorded with help experimental methods? Answering question provide psychologists, sociologists clinicians valuable insights for understanding as well concrete interaction people or groups concerned. Social that are particularly frequently confronted include mental illness, migrants ethnic minorities. In article we present results an preliminary study healthy volunteers in which used a modified...
Abstract The level of functioning individuals with autism spectrum disorder (ASD) varies widely. To better understand the neurobiological mechanism associated high-functioning ASD, we studied rare case a female patient an exceptional professional career in highly competitive academic field Mathematics. According to Research Domain Criteria (RDoC) approach, which proposes describe basic dimensions by integrating different levels information, conducted four fMRI experiments targeting (1)...
Im Bereich der Suchtherapie gibt es je nach Art Drogen unterschiedliche Therapieansätze. Während bei Patienten mit Alkohol- und Tabakabhängigkeit wie vor die Abstinenz als das sicherste Therapieziel gilt, wird Opiatabhängigkeit Substitutionstherapie meist einer Abstinenzorientierung vorgezogen, da abstinenten Opiatabhängigen im Rückfall zu tödlichen Überdosierungen kommen kann. Alkoholabhängigkeit Ansätze zur Konsumreduktion, nicht auf zielen, insbesondere Patienten, keine schwere...
Abstract Extensive research has demonstrated that rs1360780, a common single nucleotide polymorphism within the FKBP5 gene, interacts with early-life stress in predicting psychopathology. Previous results suggest carriers of TT genotype rs1360780 who were exposed to child abuse show differences structure and functional activation emotion-processing brain areas belonging salience network. Extending these findings on intermediate phenotypes psychopathology, we examined if interaction between...