A5024874344- Hematopoietic Stem Cell Transplantation
- Cryptography and Data Security
- Acute Lymphoblastic Leukemia research
- Chaos-based Image/Signal Encryption
- Hemoglobinopathies and Related Disorders
- Coding theory and cryptography
- Acute Myeloid Leukemia Research
- Neuroblastoma Research and Treatments
- Gastrointestinal disorders and treatments
- Neonatal Health and Biochemistry
- Retinoids in leukemia and cellular processes
- Complexity and Algorithms in Graphs
- Erythrocyte Function and Pathophysiology
- Iron Metabolism and Disorders
- Childhood Cancer Survivors' Quality of Life
- Neonatal Respiratory Health Research
- Antioxidant Activity and Oxidative Stress
- Lymphoma Diagnosis and Treatment
- Pediatric Urology and Nephrology Studies
- Pediatric health and respiratory diseases
- Urinary and Genital Oncology Studies
- Mesenchymal stem cell research
- Parvovirus B19 Infection Studies
- Chronic Lymphocytic Leukemia Research
- Immune Cell Function and Interaction
Ewha Womans University
2011-2024
University of Southern California
2015
Korea University
2011-2013
Ewha Womans University Medical Center
2013
National University College
2011
Samsung Medical Center
2011
Seoul St. Mary's Hospital
2011
Yeungnam University Medical Center
2011
Chonnam National University Hwasun Hospital
2011
Sungkyunkwan University
2011
A nationwide survey was conducted to clarify the clinical features and outcomes of Korean children with Langerhans cell histiocytosis (LCH). Korea Histiocytosis Working Party analyzed data 603 patients who were diagnosed LCH between 1986 2010 from 28 institutions in Korea. Median age at diagnosis 65 months (range, 0 276 mo). Bone most frequently affected organ (79.6%) followed by skin (19.2%). Initially, 419 (69.5%) had single-system involvement (SS), 85 (14.1%) multisystem (MS) disease...
Purpose Aplastic anemia (AA) is a rare hematologic disease characterized by pancytopenia and hypocellular marrow. The Korean Society of Pediatric Hematology Oncology investigated retrospectively the incidence, survival, transfusion independency according to treatment strategies in AA. Methods All questionnaires were sent members for medical records. We collected analyzed 702 available data. Results male female ratio was 1.2, median age at diagnosis 9.3 years. annual incidence children with...
We report the outcome of 236 pediatric umbilical cord blood transplantations (UCBT) performed in Korea. Given that sources grafts were mostly unrelated donors (n = 226; 95.8%), only results UCBT included for all statistics. The most frequent primary disease was acute leukemia 167). In total, 91.7% recipients seropositive cytomegalovirus (CMV). median doses nucleated cells and CD34+ 4.84 × 10(7)/kg 2.00 10(5)/kg, respectively. times to neutrophil (>0.5 10(9)/L) platelet recovery (>20 18 45...
Background Hemophagocytic lymphohistiocytosis (HLH) is a rare multiorgan disease of toxic immune activation caused by the interaction cytotoxic T cells and innate frequently involves central nervous system (CNS). Posterior reversible encephalopathy syndrome (PRES) might develop during treatment with HLH-2004 protocol from Histiocyte Society. The aims this study were to evaluate clinical outcomes putative risk factors for prediction PRES related HLH. Methods We reviewed medical records 28...
Although the hyperattenuated middle cerebral artery sign is known to be related acute infarction, volume of clot associated with it not known. We investigated whether presence or absence (HAS) on noncontrast CT (NCCT) can predict thrombus volume.We enrolled 90 consecutive patients infarction who underwent both 5- and 1.25-mm NCCT angiography (CTA). HAS was determined 5-mm retrospectively. According location thrombi, were classified into ICA (ICA terminus/ICA others), M1 (M1/both M2), M2 (M2)...
We develop a couple of new methods to reduce transmission overheads in broadcast encryption. The are based on the idea assigning one key per each partition using one-way chains after partitioning users. One method adopts <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">skipping</i> xmlns:xlink="http://www.w3.org/1999/xlink">chains</i> partitions containing up xmlns:xlink="http://www.w3.org/1999/xlink">p</i> revoked users and other...
<h3>Purpose</h3> To evaluate the long-term efficacy of a new surgical technique for correction lower lid epiblepharon using thermal contraction tarsus and retractor without lash rotating sutures. <h3>Methods</h3> A retrospective study was conducted on 112 eyes 56 patients who underwent with modified Hotz operation (group A) or procedure B). The requires that bipolar cautery applied to inferior including pretarsal orbicularis oculi muscle create rotation additional authors compared results...
BACKGROUND Hereditary hemolytic anemia (HHA) is a rare disease characterized by premature red blood cell (RBC) destruction due to intrinsic RBC defects. The Disorder Working Party of the Korean Society Hematology established and updated standard operating procedure for making an accurate diagnosis HHA since 2007. aim this study was investigate nationwide epidemiology HHA. METHODS We collected data newly diagnosed pediatric cohort (2007-2016) compared cohort's characteristics with those...
Since the successful introduction of all-trans-retinoic acid (ATRA) and its combination with anthracycline-containing chemotherapy, prognosis for acute promyelocytic leukemia (APL) has markedly improved. With ATRA anthracycline-based-chemotherapy, complete remission rate is greater than 90%, long-term survival 70-89%. Moreover, arsenic trioxide (ATO), which was introduced APL treatment in 1994, resulted excellent rates relapsed patients APL, more recently, several clinical studies have been...
<h2>Abstract</h2> Hematopoietic stem cell transplantation (HSCT) is a curative therapy for severe aplastic anemia (SAA); however, the optimal conditioning regimen HSCT with an unrelated donor has not yet been defined. A previous study using fludarabine (FLU), cyclophosphamide (Cy), and antithymocyte globulin (ATG) (study A: 50 mg/kg Cy once daily i.v. on days −9, −8, −7, −6; 30 mg/m<sup>2</sup> FLU −5, −4, −3, −2; 2.5 of ATG −2, −1) demonstrated successful engraftment (100%) but had high...
Background: The aim of this study was to investigate the prevalence, clinical and laboratory findings hereditary hemolytic anemia (HHA) in Korea from 1997 2006 develop appropriate diagnostic approach for HHA. Methods: By use questionnaires, information on HHA diagnosed collected analyzed retrospectively. A total 431 cases were enrolled 46 departments 35 hospitals. Results: overall frequency did not change through 10-year period pediatrics but show an increasing tendency internal medicine....
Background Diamond Blackfan anemia (DBA), characterized by impaired red cell production, is a rare condition that usually symptomatic in early infancy. The purpose of this study was to assess nationwide experiences DBA encountered over period 20 years. Methods medical records 56 patients diagnosed with were retrospectively reviewed from November 1984 July 2010. Fifteen institutions, including 13 university hospitals, participated study. Results male-to-female ratio 1.67:1. median age...
The purpose of this study was to investigate whether levels hTERT mRNA, as determined by real-time RT-PCR, are associated with prognosis and clinical course in AML patients. Fifty-four bone marrow specimens from 21 patients diagnosed de-novo were included. level mRNA measured the Telo TAGGG Quantification Kit (Roche Diagnostics, Mannheim, Germany), using a LightCycler Instrument Diagnostics). relative ratio (RR), which calculated dividing porphobilinogen deaminase (PBGD) housekeeping gene...
To evaluate the potential utility of (123)I-metaiodobenzylguanine ((123)I-MIBG) scintigraphy and (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET) for detection primary metastatic lesions in pediatric neuroblastoma (NBL) patients, to determine whether (18)F-FDG PET is as beneficial (123)I-MIBG imaging.We selected 8 NBL patients with significant residual mass after operation who had paired images that were obtained during follow-up. We retrospectively reviewed clinical...
NB4 cell, the human acute promyelocytic leukemia (APL) cell line, was treated with various concentrations of arsenic trioxide (ATO) to induce apoptosis, measured by staining 7-amino-actinomycin D (7-AAD) flow cytometry. 2', 7'-dichlorodihydro-fluorescein-diacetate (DCF-DA) and MitoSOX
Translocations leading to fusions between the immunoglobulin heavy chain gene (IGH) and various partner genes have been reported in B-cell precursor acute lymphoblastic leukemia (B-ALL). However, submicroscopic deletions within IGH B-ALL not rigorously assessed. In this study, we investigated characteristics of deletions, by FISH, with rearrangements. FISH was performed using commercially available dual-color break-apart rearrangement probes (Abbott/Vysis, Downers Grove, IL, USA; Kreatech,...
Since broadcast encryption was first introduced in 1993 by Fiat and Naor, many schemes have been developed. Among these, based on tree structure linear are notable. The subset difference (SD) scheme layered (LSD) small user-key size transmission overhead when the number r of revoked users is very small. punctured interval (PI) (or circular) has better not too small.In this paper, we propose a new scheme, called tree-based circle (TC) combining circular structure. In proportional to like SD...
Purpose : Iron deficiency anemia (IDA) is one of the most common nutritional deficiencies in children on a weaning diet. We investigated practices infants and children, as well their mothers' knowledge about weaning. Methods 129 with IDA 166 without (aged 6-36 months) who had visited 10 university hospitals between March 2006 July 2007. hematologic values both groups. A questionnaire was answered by mothers these children. Results The group showed significant difference from those comparison...
Renal tumors account for approximately 7% of all childhood cancers. These include Wilms tumor (WT), clear cell sarcoma the kidney (CCSK), malignant rhabdoid (MRTK), renal carcinoma (RCC), congenital mesoblastic nephroma (CMN) and other rare tumors. We investigated epidemiology pediatric in Korea.From January 2001 to December 2015, data patients (0-18 years) newly-diagnosed with at 26 hospitals were retrospectively analyzed.Among 439 (male, 240), most common was WT (n=342, 77.9%), followed by...
Purpose : Despite the seriousness of bacterial meningitis in children, there is little information on incidence, causative organisms, mortality rate and age distribution. We studied frequency by group causal pathogens, clinical characteristics children with private sector Korea. Methods The medical records containing data patients under 18 years confirmed cerebrospinal fluid (CSF) findings were retrospectively analyzed from September, 1993 to August, 2006 at Ewha Womans University Mokdong...