Bo Wei

ORCID: 0000-0001-6771-724X
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About
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Research Areas
  • Gastric Cancer Management and Outcomes
  • Sinusitis and nasal conditions
  • Metastasis and carcinoma case studies
  • Cardiac Valve Diseases and Treatments
  • Seaweed-derived Bioactive Compounds
  • Liver Disease and Transplantation
  • Liver Disease Diagnosis and Treatment
  • Phytase and its Applications
  • Asthma and respiratory diseases
  • Electrospun Nanofibers in Biomedical Applications
  • Animal Virus Infections Studies
  • Infective Endocarditis Diagnosis and Management
  • Head and Neck Cancer Studies
  • Head and Neck Surgical Oncology
  • Cardiac and Coronary Surgery Techniques
  • Hepatitis Viruses Studies and Epidemiology
  • Viral gastroenteritis research and epidemiology
  • Folate and B Vitamins Research
  • Cassava research and cyanide
  • Plant-based Medicinal Research
  • Moringa oleifera research and applications
  • Microbial infections and disease research
  • Congenital Ear and Nasal Anomalies
  • Retinoids in leukemia and cellular processes
  • Oral Health Pathology and Treatment

Sichuan University
2018-2025

West China Hospital of Sichuan University
2023-2025

Huazhong University of Science and Technology
2024

Tongji Hospital
2024

Chinese PLA General Hospital
2022

Henan Psychiatric Hospital
2018

Xinxiang Medical University
2018

Huazhong Agricultural University
2012

Texas Southern University
2008

Chronic rhinosinusitis with nasal polyps (CRSwNP) remains a challenging clinical problem due to its propensity for recurrence. However, data on the frequency of CRSwNP recurrence after surgery in China are rare.78 patients undergoing functional endoscopic sinus were followed-up 8 years and classified into recurrent non-recurrent groups. A cluster analysis based inflammatory endotypes was performed, secondarily matched phenotypes.The rate Southwest 21.8% over post-surgery. The 4 clusters: 1...

10.4193/rhin17.240 article EN Rhinology Journal 2018-09-01

Valvular heart disease (VHD), clinically manifested as a malfunction of valves, greatly threatens public health worldwide. The morbidity and mortality VHD increase significantly with age, the high prevalence in aging society has prompted urgency for effective treatment. Prosthetic valve replacement is currently recognized gold standard Bioprosthetic valves (BHVs), generally manufactured from glutaraldehyde crosslinked xenogeneic tissue, exhibited better hemodynamics lower thrombogenicity...

10.2139/ssrn.5087211 preprint EN 2025-01-01

Transjugular intrahepatic portosystemic shunt (TIPS) is an established procedure for managing portal hypertension in cirrhotic patients, but the impact of post-TIPS overt hepatic encephalopathy (OHE) on survival remains controversial. While its effect short-term well-documented, long-term implications remain unclear. This study aims to investigate OHE mortality patients variceal bleeding, focusing timing and predictive value beyond first year post-TIPS. A multicenter, retrospective cohort...

10.1111/apt.18509 article EN Alimentary Pharmacology & Therapeutics 2025-02-17

The prevalence of heart valve disease (HVD) has escalated worldwide, because population aging. Currently, artificial replacement is considered the most effective treatment for HVD. complexity and risk have been markedly reduced with development minimally invasive interventional techniques, which resulted in more widespread implantation bioprosthetic valves (BHVs); however, they still present defects including thrombosis, poor cytocompatibility, immune responses, calcification, reduces their...

10.1021/acsami.5c01314 article EN ACS Applied Materials & Interfaces 2025-03-14

HER2 expression has a central role in breast cancer carcinogenesis and is associated with poor prognosis. Lately, identification of HER2-low been proposed to select patients for novel HER2-directed chemotherapy includes cancers immunohistochemistry (IHC) 1+or 2+with negative fluorescence situ hybridization (FISH), encompassing approximately 55-60% all carcinomas. Neoadjuvant chemotherapy(NAC) an important therapeutic modality (BC). Immune inflammatory biomarkers have reportedly linked the...

10.3389/fonc.2025.1437677 article EN cc-by Frontiers in Oncology 2025-03-14

High thrombogenicity and shortened lifespan have limited the application of mechanical valves bioprosthetic valves, respectively. Tissue engineering heart valve (TEHV) holds significant potential as a favorable prosthetic to overcome limitations current featuring capabilities self-pairing adaptive remodeling. However, TEHVs, mainly fabricated from decellularized xenogeneic (DHV), still challenges such thrombosis, inferior endothelialization, immune responses. Herein, drug-loaded...

10.1021/acsami.4c22022 article EN ACS Applied Materials & Interfaces 2025-03-22

A simple, specific, sensitive, and rapid high performance liquid chromatography (HPLC) method for the determination of griseofulvin in small volumes rat plasma was developed validated using warfarin as an internal standard. Biological sample preparation involved simple extraction with acetonitrile, followed by dilution aqueous mobile phase buffer (20 mM sodium dihydrogen phosphate, pH 3.5) to eliminate any chromatographic solvent effects. Griseofulvin were baseline separated quantitated on a...

10.4137/aci.s953 article EN cc-by-nc Analytical Chemistry Insights 2008-01-01

OBJECTIVE To clarify the important factors affecting prognosis of patient with gastric carcinoma. METHODS The data 2335 cases resected carcinoma from Jan. 1996 to Dec. 2005 were studied by using univariate analysis and multivariate regression analysis. RESULTS Male patients accounted for 81.0% female 19.0%. ratio male was 4.2: 1.0. Patients under 50 years old 77.2%. Two hundred seventy-five early cancer, accounting 11.8%, another 2060 advanced 88.2%. Tumor diameter 72.8% more than 4 cm 69.6%...

10.3760/cma.j.issn.1671-0274.2007.05.009 article EN 2007-09-01

We investigated the characteristics of microbial community nasal sinuses in patients with chronic rhinosinusitis polyps (CRSwNP) and identified correlations microbiome inflammatory microenvironment cavity.

10.1016/j.asjsur.2023.08.096 article EN cc-by-nc-nd Asian Journal of Surgery 2023-08-31

To investigate the correlation between impulse oscillometry system examination indicators and conventional pulmonary ventilation function.

10.3760/cma.j.cn112138-20240410-00231 article EN PubMed 2024-11-01

Abstract All age groups are affected by one of the most prevalent chronic medical disorders globally: rhinosinusitis (CRS). Its estimated incidence is 10.9% in Europe, 13% China, and 12.3% United States. For many years, 16S rRNA gene has been backbone sequence-based bacterial study. Still, it only recently that possibility high-throughput sequencing entire feasible. A unique regulation mechanism known as “RNA silencing” limits transcript level either starting specific RNA degradation or...

10.1101/2024.11.11.622768 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-11-12

1. Inositol hexanicotinate (IHN) is an ester of the anti-hyperlipidemic drug nicotinic acid (NA). This study assessed hydrolysis rate IHN in human and rat plasma, pharmacokinetics using a animal model.2. (10 or 50 µg/mL) was incubated plasma at 37 °C for 72 h. Kinetic parameters were determined based on disappearance appearance NA. The mean NA half-lives 1.07 3.93 h 0.152 2.68 plasma. Increasing initial concentration to µg/mL increased half-life 4.66 6.47 h, respectively.3. After single 100...

10.3109/00498254.2012.762591 article EN Xenobiotica 2013-01-24

目的: 探讨近端胃切除间置空肠残胃-空肠双通道吻合术在SiewertⅡ~Ⅲ型食管胃结合部腺癌手术中的临床疗效。 方法: 采用回顾性队列研究方法。收集江苏省丹阳市人民医院2017年12月至2019年3月期间收治的行近端胃切除术的45例SiewertⅡ和Ⅲ型食管胃结合部腺癌患者临床资料。根据消化道重建方式的不同,分为间置空肠残胃-空肠双通道吻合组(双通道组,15例)和食管残胃吻合术组(单通道组,30例)。间置空肠残胃-空肠双通道吻合简要步骤:行空肠-食管残端端侧吻合(第一吻合口),关闭空肠残端;行残胃大弯侧与空肠侧侧吻合(第二吻合口),关闭残胃断端;行近端空肠与远端空肠侧侧吻合(第三吻合口),关闭空肠残端。两组基线资料的比较,差异有统计学意义,具有可比性(均P>0.05)。比较两组术中、术后及随访情况。 结果:...

10.3760/cma.j.cn.441530-20190828-00327 article ZH-CN PubMed 2020-04-25
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