A5042397011- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Pluripotent Stem Cells Research
- Neuroscience and Neural Engineering
- Cardiac electrophysiology and arrhythmias
- CRISPR and Genetic Engineering
- Ion channel regulation and function
- Electrochemical Analysis and Applications
- DNA and Nucleic Acid Chemistry
- Electrochemical sensors and biosensors
- Chronic Kidney Disease and Diabetes
- Lung Cancer Treatments and Mutations
- Drug Transport and Resistance Mechanisms
- Hormonal Regulation and Hypertension
- Molecular Sensors and Ion Detection
- NF-κB Signaling Pathways
- Tuberculosis Research and Epidemiology
- Infectious Encephalopathies and Encephalitis
- Advanced Photocatalysis Techniques
- HIV Research and Treatment
- Renin-Angiotensin System Studies
- Esophageal Cancer Research and Treatment
- Advanced Nanomaterials in Catalysis
- Nanoparticle-Based Drug Delivery
- Electrolyte and hormonal disorders
Anhui Provincial Hospital
2021-2025
University of Science and Technology of China
2020-2025
Ollscoil na Gaillimhe – University of Galway
2019-2024
Shenyang Pharmaceutical University
2023-2024
Hunan University
2018-2024
Sichuan University
2024
Northwestern University
2023-2024
Shandong Provincial Hospital
2021
Shandong University
2021
Hunan International Economics University
2020
Abstract Norfloxacin (NOF) is an environmentally harmful and ubiquitous aquatic pollutant with extensive production application. In this study, a novel composition named carbon-based composite photocatalytic material of zinc oxide sulphide (ZnO/ZnS@BC) was successfully obtained by the impregnation-roasting method to remove NOF under UV-light. Scanning electron microscopy, X-ray photoelectron spectroscopy, transmission microscopy energy dispersive spectrometer characterised composition....
Genome-wide association studies and candidate gene have identified more than 180 genetic variants statistically associated with anthracycline-induced cardiotoxicity (AIC). However, the lack of functional validation has hindered clinical translation these findings. The aim this study was to functionally validate all genes AIC using human induced pluripotent stem cell–derived cardiomyocytes (hiPSC-CMs). Through a systemic literature search, 80 containing significantly were identified....
In the present work, a series of magnetically separable Fe3O4/g-C3N4/MoO3 nanocomposite catalysts were prepared. The as-prepared characterized by XRD, EDX, TEM, FT-IR, UV-Vis DRS, TGA, PL, BET and VSM. photocatalytic activity materials was evaluated catalytic degradation tetracycline solution under visible light irradiation. Furthermore, influences weight percent MoO3 scavengers reactive species on investigated. results showed that (30%) nanocomposites exhibited highest removal ability for...
BackgroundSomatic mutations of mitochondrial DNA (mtDNA) have been extensively identified mainly by traditional Sanger sequencing technology in various cancer types. However, low detection sensitivity methods greatly limits the comprehensive profiling mtDNA somatic cancers, especially hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Moreover, functional roles mutation HBV-related hepatocarcinogenesis not systematically revealed.Patients and methodsNext-generation (NGS)...
Human cystatin C is a single non-glycosylated polypeptide chain consisting of 120 amino acid residues. Its concentration in the circulation mainly determined by glomerular filtration rate. However, non-renal factors, i.e., drugs, may dramatically affect its levels circulation. The aim this study was to evaluate effect corticosteroid treatment on serum patients with symptomatic heart failure.Fifty-six failure were treated prednisone. Concentrations and creatinine recorded at baseline, after...
The efficacy of chemotherapeutic agents for colon cancer treatment is limited by multidrug resistance (MDR) and insufficient intracellular release the administered nanomedicine. To overcome these limitations, we constructed a pH/ROS cascade-responsive self-accelerating drug nanoparticle system (PLP-NPs) multidrug-resistant cancer. PLP-NPs comprised reactive oxygen species (ROS)-sensitive polymeric paclitaxel (PTX) prodrug (DEX-TK-PTX), pH-sensitive poly(l-histidine) (PHis), beta-lapachone...
Abstract Background Chemoresistance is one of the major obstacles for tumor treatment. Circular RNAs (circRNAs) have been confirmed to play vital roles in chemoresistance cancer, including esophageal squamous cell carcinoma (ESCC). We investigated and mechanisms circ_0007142 cisplatin (DDP) resistance ESCC. Methods Quantitative real‐time polymerase chain reaction (qRT‐PCR) was conducted determine levels circ_0007142, DOCK1 mRNA, microRNA‐494‐3p (miR‐494‐3p) LIM And SH3 Protein 1 (LASP1)...
We proposed, for the first time, a novel colorimetric assay sensitive detection of kanamycin based on aptamer-regulated peroxidase-like activity Co 3 O 4 NPs.
The role of electrostatic and hydrophobic interactions in the binding penetration β-lactoglobulin (βLG) to preformed lipid membranes was studied using various phospholipid micelles vesicles. Zwitterionic lysophospholipid are able induce β-sheet α-helix transition, as judged by circular dichroism (CD), but degree transition is dramatically below amount required above that for anionic phospholipids with equivalent hydrocarbon chains. Anionic short chains only low α-helical content βLG compared...
Background: Several studies have shown that non-renal factors such as corticosteroids may increase plasma cystatin C levels without affecting kidney function. However, the mechanisms underlying this are unclear. We hypothesized in by promoting its production tissues. In present study, we aimed to test our hypothesis rats investigating effect of on tissues and glomerular filtration rate (GFR), measured gold standard method (i.e., inulin clearance).Results: Dexamethasone treatment was...
Radiotherapy plays an important role in controlling the local recurrence of esophageal cancer after radical surgery. Segmentation clinical target volume is a key step radiotherapy treatment planning, but it time-consuming and operator-dependent. This paper introduces deep dilated convolutional U-network to achieve fast accurate auto-segmentation The U-network, which integrates advantages convolution end-to-end architecture that enables rapid training testing. A module for extracting...
Background Arginine vasopressin dependent antidiuresis plays a key role in water‐sodium retention heart failure. In recent years, the of glucocorticoids control body fluid homeostasis has been extensively investigated. Glucocorticoid deficiency can activate V2R (vasopressin receptor 2), increase aquaporins expression, and result hyponatremia, all which be reversed by glucocorticoid supplement. Methods Results Heart failure was induced coronary artery ligation for 8 weeks. A total 32 rats...
Despite sustained effort, the prognosis of lung cancer remains poor and therapeutic responses are limited. Cell movement ability is a prerequisite for metastasis, which involves focal adhesion kinase (FAK)‑mediated cell migration invasion via complex formation with Src. Hence, FAK‑Src signaling might be an effective target anti‑cancer treatment. β‑elemene, major component elemene extracted from Curcuma Rhizoma, exhibits broad‑spectrum anti‑tumor properties. However, role β‑elemene in...