A5114777993- Winter Sports Injuries and Performance
- HIV, Drug Use, Sexual Risk
- Epigenetics and DNA Methylation
- Sports Performance and Training
- Trace Elements in Health
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Sports injuries and prevention
- Heavy Metal Exposure and Toxicity
- Cardiovascular Disease and Adiposity
- Air Quality and Health Impacts
- Catalytic Processes in Materials Science
- Lower Extremity Biomechanics and Pathologies
- Adolescent Sexual and Reproductive Health
- Adipokines, Inflammation, and Metabolic Diseases
- Folate and B Vitamins Research
- Animal Nutrition and Physiology
- Vehicle emissions and performance
- Cardiovascular Health and Risk Factors
- Gut microbiota and health
- Respiratory viral infections research
- Air Quality Monitoring and Forecasting
- Influenza Virus Research Studies
- HIV, TB, and STIs Epidemiology
- Angiogenesis and VEGF in Cancer
Huazhong University of Science and Technology
2014-2024
South China Agricultural University
2024
Chinese Academy of Sciences
2024
Shandong Agricultural University
2024
Taiyuan University of Technology
2018-2024
People's Hospital of Cangzhou
2022
Tongde Hospital of Zhejiang Province
2017-2021
Ministry of Ecology and Environment
2021
Taishan Medical University
2018-2019
Obstetrics and Gynecology Hospital of Fudan University
2019
To investigate the associations of sleep duration, midday napping, quality, and change in duration with risk incident stroke subtypes.Among 31,750 participants aged 61.7 years on average at baseline from Dongfeng-Tongji cohort, we used Cox regression models to estimate hazard ratios (HRs) 95% confidence intervals (CIs) for stroke.Compared sleeping 7 <8 hours/night, those reporting longer (≥9 hours/night) had a greater total (hazard ratio [HR] 1.23; interval [CI] 1.07-1.41), while shorter (<6...
Acute coronary syndrome (ACS) is a leading cause of death worldwide. Immune functions play vital role in ACS development; however, whether epigenetic modulation contributes to the regulation blood immune cells this disease has not been investigated.We conducted an epigenome-wide analysis with circulating identify differentially methylated genes ACS.We examined genome-wide methylation whole 102 patients and 101 controls using HumanMethylation450 array, externally replicated significant...
Smoking is a risk factor for many human diseases. DNA methylation has been related to smoking, but genome-wide data smoking in Chinese populations limited.We aimed investigate epigenome-wide relation population.We measured the levels at > 485,000 CpG sites (CpGs) from leukocytes using array and conducted meta-analysis of total 596 participants. We further evaluated associations smoking-related CpGs with internal polycyclic aromatic hydrocarbon (PAH) biomarkers their correlations expression...
Background: Aging is related to an increased risk of morbidity and mortality affected by environmental factors. Exposure polycyclic aromatic hydrocarbons (PAHs) associated with adverse health outcomes; but the association such exposure DNA methylation aging, a novel aging marker, unclear. Objectives: Our aim was investigate PAH aging. Methods: We trained validated age predictor suitable for Chinese populations using whole blood data in 989 160 Caucasians. defined two indicators: Δage, as...
This is the third paper in series Catalogue of fungi China that aims to systematically and promptly publish Chinese fungal species. In this series, we focus on macrofungi from southern border area Xizang, a previously less concerned region. A total 15 new species six orders, 11 families, 12 genera Agaricomycetes, Basidiomycota are described. Both morphological phylogenetic analyses support identity these their taxonomic placements. addition, one combination Trechispora cryptomerioides...
C-reactive protein (CRP) is a well-recognized biomarker of inflammation, which can be used as predictor cardiovascular disease. Evidence have suggested exposure to multiple metals/metalloids may affect immune system and give rise However, it lack study comprehensively evaluate the association metals CRP, interactions between metals, gene-metal interaction in relation CRP levels. To explore associations plasma with serum test on levels CRP. We included 2882 participants from Dongfeng-Tongji...
Abstract Background Acute coronary syndrome (ACS) is a cardiac emergency with high mortality. Exposure to copper (Cu) concentration has been linked ACS. However, whether DNA methylation contributes the association between Cu and ACS unclear. Methods We measured level at > 485,000 cytosine-phosphoguanine sites (CpGs) of blood leukocytes using Human Methylation 450 Bead Chip conducted genome-wide meta-analysis plasma in total 1243 Chinese individuals. For Cu-related CpGs, we evaluated their...
A study of female sex workers in China, found alarmingly high prevalence methamphetamine use. Methamphetamine users were more likely to be single, younger, inconsistent condom users, and have syphilis.
Dimetridazole (DMZ) is a broad-spectrum anti-anaerobic and antiprotozoal drug extensively used for the control of blackhead disease in poultry (especially turkeys). The presence DMZ its metabolites animal food poses potential risks to human health. In this study, we developed high-performance liquid chromatography tandem mass spectrometry (HPLC/MS-MS) method precise detection metabolite 2-hydroxymethyl-1-methyl-5-nitroimidazole (HMMNI). Our results demonstrate strong linear relationship (r 2...
Abstract Background and purpose The components of ideal cardiovascular health (CVH) metrics have been shown to be associated with non‐alcoholic fatty liver disease (NAFLD). present study aimed determine the association between CVH NAFLD. Methods A total 10,511 participants (47.26% men) aged 18 92 years were selected from Jidong Kailuan communities. Ideal was based on 7 metrics: smoking, body mass index (BMI), physical activity, diet, cholesterol, blood pressure fasting glucose. NAFLD...
Previously identified common variants explain only a small fraction of the trait heritability and at most loci identities underlying causal genes their functional still remain unknown. To identify low-frequency rare coding that influence lipid levels, we conducted meta-analysis exome-wide association studies in 14,473 Chinese subjects, followed by joint analysis with 1000 genomes imputed data from 6,534 samples. We replicated 24 previously reported significance (P < 3.3 × 10 - 7), including...
Background Mounting evidence suggests that circulating microRNAs (miRNAs) are critical indicators of cardiovascular disease. However, prospective studies linking miRNAs to incident acute coronary syndrome (ACS) limited, and the underlying effect associated miRNA on ACS remains unknown. Methods Results Based a 2-stage nested case-control design within Dongfeng-Tongji cohort, we profiled plasma from 23 pairs cases controls by microarray validated candidate in 572 using quantitative real-time...