B. A. Malyarchuk
A5084548647- Forensic and Genetic Research
- Genetic diversity and population structure
- Yersinia bacterium, plague, ectoparasites research
- Forensic Anthropology and Bioarchaeology Studies
- Metabolism and Genetic Disorders
- Mitochondrial Function and Pathology
- Genomics and Phylogenetic Studies
- Metabolomics and Mass Spectrometry Studies
- Molecular Biology Techniques and Applications
- Nutrition, Genetics, and Disease
- Race, Genetics, and Society
- Animal Ecology and Behavior Studies
- Digestive system and related health
- RNA and protein synthesis mechanisms
- Identification and Quantification in Food
- DNA Repair Mechanisms
- Genetics and Physical Performance
- Muscle metabolism and nutrition
- Indigenous Studies and Ecology
- Genetic Associations and Epidemiology
- Wildlife Ecology and Conservation
- Environmental and Biological Research in Conflict Zones
- Amphibian and Reptile Biology
- Genetic and phenotypic traits in livestock
- Isotope Analysis in Ecology
Institute of Biological Problems of the North
2016-2025
Russian Academy of Sciences
2016-2025
Far Eastern Branch of the Russian Academy of Sciences
2011-2024
Interdisciplinary Scientific Research
2023
Hokkaido University
2015
Severtsov Institute of Ecology and Evolution
2015
Institute of Chemistry, Far Eastern Branch of the Russian Academy of Sciences
2015
Kansai University
2015
Fukuyama University
2015
Institute for Complex Analysis of Regional Problems
2015
How and when the Americas were populated remains contentious. Using ancient modern genome-wide data, we found that ancestors of all present-day Native Americans, including Athabascans Amerindians, entered as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) after more an 8000-year isolation period in Beringia. After their arrival to Americas, ancestral Americans diversified into two basal genetic branches around 13 ka, one is now dispersed across North South...
It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50–100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ancient DNA calibration, date the Y-chromosomal most recent common ancestor (MRCA) Africa at 254 (95% CI 192–307) kya and detect cluster major founder haplogroups narrow time interval 47–52 kya,...
It has been often stated that the overall pattern of human maternal lineages in Europe is largely uniform. Yet this uniformity may also result from an insufficient depth and width phylogenetic analysis, particular predominant western Eurasian haplogroup (Hg) H comprises nearly a half European mitochondrial DNA (mtDNA) pool. Making use coding sequence information 267 mtDNA Hg sequences, we have analyzed 830 genomes, 11 European, Near Middle Eastern, Central Asian, Altaian populations. In...
The Turkic peoples represent a diverse collection of ethnic groups defined by the languages. These have dispersed across vast area, including Siberia, Northwest China, Central Asia, East Europe, Caucasus, Anatolia, Middle East, and Afghanistan. origin early dispersal history is disputed, with candidates for their ancient homeland ranging from Transcaspian steppe to Manchuria in Northeast Asia. Previous genetic studies not identified clear-cut unifying signal peoples, which lends support...
Following the dispersal out of Africa, where hominins evolved in warm environments for millions years, our species has colonised different climate zones world, including high latitudes and cold environments. The extent to which human habitation (sub-)Arctic regions been enabled by cultural buffering, short-term acclimatization genetic adaptations is not clearly understood. Present day indigenous populations Siberia show a number phenotypic features, such as increased basal metabolic rate,...
More than a half of the northern Asian pool human mitochondrial DNA (mtDNA) is fragmented into number subclades haplogroups C and D, two most frequent throughout northern, eastern, central Asia America. While there has been considerable recent progress in studying variation eastern America at complete genome resolution, little comparable data available for regions such as southern Siberia – area where haplogroups, including likely diversified. This gap our knowledge causes serious barrier...
Abstract Humans have more copies of amylase genes than other primates. It is still poorly understood, however, when the copy number expansion occurred and whether its spread was enhanced by selection. Here we assess numbers in a global sample 480 high coverage genomes find that regions flanking locus show notable depression genetic diversity both African non-African populations. Analysis variation these supports model an early selective sweep human lineage after split humans from...
Phylogenetic relationships between the extinct woolly mammoth (Mammuthus primigenius), and Asian (Elephas maximus) African savanna (Loxodonta africana) elephants remain unresolved. Here, we report sequence of complete mitochondrial genome (16,842 base pairs) a extracted from permafrost-preserved remains Pleistocene epoch--the oldest determined to date. We demonstrate that well-preserved fragments, as long approximately 1,600-1700 pairs, can be retrieved pre-Holocene an species....
It is generally accepted that the most ancient European mitochondrial haplogroup, U5, has evolved essentially in Europe. To resolve phylogeny of this we completely sequenced 113 genomes (79 U5a and 34 U5b) central eastern Europeans (Czechs, Slovaks, Poles, Russians Belorussians), reconstructed a detailed phylogenetic tree, incorporates previously published data. Molecular dating suggests coalescence time estimate for U5 approximately 25-30 thousand years (ky), 16-20 20-24 ky its...
Due to its pivotal geographical location and proximity transcontinental migratory routes, Iran has played a key role in subsequent migrations, both prehistoric historic, between Africa, Asia Europe. To shed light on the genetic structure of Iranian population as well expansion patterns movements which affected this region, complete mitochondrial genomes 352 Iranians were obtained. All populations studied here exhibit similarly high diversity values comparable other groups from Caucasus,...
To shed more light on the processes leading to crystallization of a Slavic identity, we investigated variability complete mitochondrial genomes belonging haplogroups H5 and H6 (63 mtDNA genomes) from populations Eastern Western Slavs, including new samples Poles, Ukrainians Czechs presented here. Molecular dating implies formation approximately 11.5–16 thousand years ago (kya) in areas southern Europe. Within ancient haplogroup H6, dated at around 15–28 kya, there is subhaplogroup H6c, which...
To investigate the origin and evolution of aboriginal populations South Siberia, a comprehensive mitochondrial DNA (mtDNA) analysis (HVR1 sequencing combined with RFLP typing) 480 individuals, representing seven Altaic-speaking (Altaians, Khakassians, Buryats, Sojots, Tuvinians, Todjins Tofalars), was performed. Additionally, HVR2 sequence information obtained for 110 Altaians, providing, in particular, some novel details East Asian mtDNA phylogeny. The total sample revealed 81% (M*, M7, M8,...
Mitochondrial DNA (mtDNA) sequence variation was examined in Poles (from the Pomerania-Kujawy region; n = 436) and Russians three different regions of European part Russia; 201), for which two hypervariable segments (HVS I HVS II) haplogroup-specific coding region sites were analyzed. The use mtDNA RFLP analysis made it possible to distinguish parallel mutations that occurred at particular II during evolution. In total, identified 73 nucleotide (17.8%) 31 (7.73%). classification...
Mitochondrial DNA (mtDNA) sequence variation was examined in Poles (from the Pomerania‐Kujawy region; n = 436) and Russians three different regions of European part Russia; 201), for which two hypervariable segments (HVS I HVS II) haplogroup‐specific coding region sites were analyzed. The use mtDNA RFLP analysis made it possible to distinguish parallel mutations that occurred at particular II during evolution. In total, identified 73 nucleotide (17.8%) 31 (7.73%). classification...
To resolve the phylogeny of certain mitochondrial DNA (mtDNA) haplogroups in eastern Europe and estimate their evolutionary age, a total 73 samples representing U4, HV*, R1 were selected for complete genome sequencing from collection about 2,000 control region sequences sampled (Russians, Belorussians, Ukrainians) western (Poles, Czechs, Slovaks) Slavs. On basis whole-genome resolution, we fully characterized number (HV3, HV4, U4a1, U4a2, U4a3, U4b, U4c, U4d, R1a) that previously described...
With the aim of uncovering all most basal variation in northern Asian mitochondrial DNA (mtDNA) haplogroups, we have analyzed mtDNA control region and coding sequence 98 Altaian Kazakhs from southern Siberia 149 Barghuts Inner Mongolia, China. Both populations exhibit prevalence eastern Eurasian lineages accounting for 91.9% 60.2% Kazakhs. The strong affinity central Asia has been revealed, reflecting both influences inhabitants essential genetic interaction with Altai indigenous...
Summary Mitochondrial DNA variability in two Slavonic‐speaking populations of the northwestern Balkan peninsula, Bosnians (N = 144) and Slovenians 104), was studied by hypervariable segments I II (HVS II) sequencing restriction fragment‐length polymorphism (RFLP) analysis mtDNA coding region. The majority detected Southern Slavonic falls into common West Eurasian mitochondrial haplogroups (e.g., H, pre‐V, J, T, U, K, I, W, X). About 2% Bosnian mtDNAs encompass East African lineages M L1b,...