A5100782675- Dental materials and restorations
- Dental Implant Techniques and Outcomes
- Orthodontics and Dentofacial Orthopedics
- Dental Radiography and Imaging
- Telomeres, Telomerase, and Senescence
- Protein Hydrolysis and Bioactive Peptides
- Rheumatoid Arthritis Research and Therapies
- Bone Tissue Engineering Materials
- Bone Metabolism and Diseases
- Infant Nutrition and Health
- Digital Imaging in Medicine
- Reproductive Biology and Fertility
- Temporomandibular Joint Disorders
- Cancer Research and Treatments
- Genetically Modified Organisms Research
- Genetics, Aging, and Longevity in Model Organisms
- Obstructive Sleep Apnea Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Insect Resistance and Genetics
- Antioxidant Activity and Oxidative Stress
- Microbial bioremediation and biosurfactants
- Ear Surgery and Otitis Media
- Anatomy and Medical Technology
- Meta-analysis and systematic reviews
- Food composition and properties
Peking University
2013-2024
Stomatology Hospital
2023-2024
Sichuan University
2024
State Key Laboratory of Oral Diseases
2024
Air Force Medical University
2024
Xijing Hospital
2024
Zhejiang University of Technology
2024
Zhejiang University
2024
Inner Mongolia University
2024
University of Geneva
2021-2023
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial fibroblast hyperplasia and bone erosion. Fibroblast-like synoviocytes (FLS) play pivotal role in RA pathogenesis through aggressive migration matrix invasion, certain proinflammatory cytokines may affect synoviocyte invasion. Whether interleukin (IL)-21 influences this process remains controversial. Here, we evaluated the potential regulatory effect of IL-21 on migration, invasion metalloproteinase (MMP)...
Impaired wound healing is a major clinical problem in patients with diabetes and the leading cause of lower limb amputation. This study aimed to observe effects small molecule oligopeptides isolated from sea cucumber (SCCOPs) on process diabetic mice. Ninety db/db male mice were divided into five groups, including model control group, whey protein group (0.50 g/kg) three SCCOPs dose groups (0.25 g/kg, 0.50 g/kg 1.00 g/kg). Additionally, 18 db/m used as normal group. After full-thickness...
This study aimed to investigate the immunomodulatory effects of walnut (Juglans regia L.) oligopeptides (WOPs). Female BALB/c mice were randomly assigned control, whey protein control and three WOPs groups, given deionized water, 220 mg/kg BW protein, 110, 440 daily through drinking water for 30 days, respectively. The immonomodulatory activity determination involved innate adaptive immunity, spleen T lymphocyte subpopulations, serum cytokine immunoglobulin levels. Our results showed that...
To evaluate the clinical performance of adhesively bonded lithium disilicate glass-ceramic (LDG) partial-coverage crowns in restoring posterior endodontically treated teeth (ETT).
Filopodia, which are actin-rich finger-like membrane protrusions, have an important role in cell migration and tumor metastasis. Here we identify 13 novel calumenin (Calu) isoforms (Calu 3–15) produced by alternative splicing, find that Calu-15 promotes filopodia formation migration. shuttles between the nucleus cytoplasm through interacting with importin α, Ran GTPase, Crm1. The phosphorylation of threonine at position 73 (Thr-73) casein kinase 2 (CK2) is essential for nuclear import...
Anti-citrullinated protein/peptide antibodies (ACPA) play important roles in the pathogenesis of rheumatoid arthritis (RA). ACPA-positive (ACPA+ ) and ACPA-negative (ACPA- RA were suggested to be different disease subsets, with distinct differences genetic variation clinical outcomes. The aims present study compare gene expression profiles ACPA+ ACPA- RA, identify novel candidate signatures that might serve as therapeutic targets. Comprehensive transcriptome analysis peripheral blood...
Objectives: To compare the prevalence of asymptomatic oral candidal carriage in healthy volunteers with human immunodeficiency virus (HIV)‐positive patients China, as well to investigate relationship between CD4 + lymphocyte count and colonization or candidiasis. Methods: Oral candidiasis were investigated 101 HIV‐infection seen at Youan Hospital, Beijing, China. Two hundred seventeen involved a control. Culture from saliva was used test for presence Candida . measured by flow cytometry. All...
Abstract Aim This study aimed to investigate the influence of titanium base (ti‐base) abutment macro‐ and micro‐geometry on mechanical stability polymer‐infiltrated ceramic network (PICN) screw‐retained implant‐supported single crowns (iSCs). Materials Methods Twelve specimens per group were used, comprising six different implant/ti‐base combinations restored with PICN iSCs: Nb‐T (gingival height [GH]: 1.5 mm, prosthetic [PH]: 4.3 mm), CC (GH: 0.8 PH: CC‐P 7 Nb‐V 6 St 5.5 Th 0.5 9 mm). The...
Peptic ulcer has a serious impact on people’s health around the world, and traditional medicines can cause adverse reactions. This study investigated protective effects of tilapia collagen oligopeptides (TCOPs) gastroduodenal injury. Seventy-two specific pathogen-free (SPF) male Sprague Dawley (SD) rats were randomly divided into six groups according to body weight: normal control group, ethanol whey protein group (500 mg/kg BW), three TCOPs dose (250, 500, 1000 BW). After intragastric...
Several lines of evidence suggest an inhibitory role dietary nucleotides (NTs) against oxidative stress and inflammation, which promote senescence in age-associated cardiovascular diseases. We sought to test whether the NTs could retard hydrogen peroxide (H2O2)-induced human umbilical vein endothelial cells (HUVECs) elucidate efficiency different as well potential mechanism. Senescence was induced HUVECs by 4 h exposure 200 µM H2O2 confirmed using senescence-associated-β-galactosidase...
To determine if a home sleep apnea test (HSAT) using type III portable monitor (PM), Nox-T3 (Nox Medical, Inc., Reykjavik, Iceland), detects obstructive in pregnant women.
The skin, serving as the body’s primary defense against external elements, plays a crucial role in protecting body from infections and injuries, well maintaining overall homeostasis. Skin aging, common manifestation of aging process, involves gradual deterioration its normal structure repair mechanisms. Addressing issue skin is increasingly imperative. Multiple pieces evidence indicate potential anti-aging effects exogenous nucleotides (NTs) through their ability to inhibit oxidative stress...
Intracerebral hemorrhage (ICH) is a severe stroke subtype with high morbidity, disability, and mortality rates. Currently, no biomarkers for ICH are available use in clinical practice. We aimed to explore the roles of RNAs pathogenesis identify potential diagnostic biomarkers.
Survivability and tolerance of polycyclic aromatic hydrocarbon (PAH)-degrading bacteria in harsh environments, especially under varying temperatures, are a bottleneck for the effective application situ bioremediation. In this study, temperature adaptation system (TAS) was constructed by combining customized thermotolerant with cold-resistant to realize temperature-responsive regulation PAH-degrading mesophilic bacterium Novosphingobium pentaromativorans US6-1. The innovative dual-pronged TAS...
This study evaluated the effects of manipulator level (ML) on implant scan body (ISB) seating. It also investigated ISB vertical deviation with various levels tightening torque.In total, 10 standard acrylic resin models were prepared first molar site. ISBs placed by six operators three MLs, manually and a torque 15 Ncm using an electronic driver. Digital scans completed intraoral device. After superimposition in software, was compared between manual operation. One experienced operator then...
Despite increased attention to open science and transparency, questionable research practices (QRPs) remain common, studies published using QRPs will a part of the record for some time. A particularly common type QRP involves multiple testing, in forms this, researchers report only selection tests conducted. Methodological investigations testing have often focused on implications single study, as well how these can increase likelihood false positive results. However, it is illuminating...
The clinical demand for occlusal reconstruction increases rapidly with increasing number of patients who have lost their normal occlusion because tooth wear and dentition defects. Occlusal is a special type restoration defined as comprehensive the function stomatognathic system by reestablishing uniform stable relationship between upper lower dentitions. analysis an important part to achieve accurate design adjustment. Digital was conducted monitor movement mandible obtain related data...
Aims: To investigate the diagnostic value of oviduct glycoprotein 1 (OVGP1) levels for polycystic ovary syndrome (PCOS). Materials and Methods: Serum OVGP1 concentrations were measured by enzyme-linked immunosorbent assay (ELISA). Associations between endocrine parameters evaluated Spearman's correlation analysis. Diagnostic capacity was assessed utilizing machine learning algorithms receiver operating characteristic (ROC) curves. Results: significantly decreased in PCOS patients correlated...