A5103109831- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Neurological Disease Mechanisms and Treatments
- Tryptophan and brain disorders
- Antiplatelet Therapy and Cardiovascular Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Health and Mental Health
- Diet and metabolism studies
- Atrial Fibrillation Management and Outcomes
- Gut microbiota and health
- Platelet Disorders and Treatments
- Spectroscopy and Chemometric Analyses
- Spectroscopy Techniques in Biomedical and Chemical Research
- Lipoproteins and Cardiovascular Health
- Balance, Gait, and Falls Prevention
- Fault Detection and Control Systems
- Vaccine Coverage and Hesitancy
- Misinformation and Its Impacts
- Cardiovascular Health and Risk Factors
- Cardiac, Anesthesia and Surgical Outcomes
- Health disparities and outcomes
- Bladder and Urothelial Cancer Treatments
Wenzhou Medical University
2014-2025
Dongyang People's Hospital
2014-2025
Beijing Tsinghua Chang Gung Hospital
2024
Tsinghua University
2024
Inspire Institute
2024
Purdue University West Lafayette
2022
Mackay Base Hospital
2020
Soochow University
2012
First Affiliated Hospital of Soochow University
2012
Taihe Hospital
2009
Introduction: With the approval of COVID-19 vaccinations for children and adolescents in China, parental vaccine hesitancy will emerge as a new challenge with regard to administration these vaccines. However, little is known regarding this well regional differences that may exist between parents from Shandong vs. Zhejiang. Methods: To assess issues, an online survey was conducted via Wenjuanxing platform over period July 22 August 14, 2021. Parents Zhejiang were recruited Wechat groups...
Current evidence provides limited support for the superiority of endovascular thrombectomy (EVT) in patients with M2 segment middle cerebral artery occlusion. We aim to investigate whether imaging features occlusion impact effectiveness EVT.
ABSTRACT Motion artifact removal is a critical issue in functional near‐infrared spectroscopy (fNIRS) analysis tasks, with traditional methods relying heavily on expert‐based knowledge and optimal selection of model parameters within brain regions. In this paper, we propose deep learning denoising based long short‐term memory (LSTM)‐autoencoder (viz., LSTM‐AE) to reduce motion artifacts. By training neural network reconstruct hemodynamic response coupled neuronal activity, LSTM‐AE achieves...
Background Stroke-associated pneumonia (SAP) is a common and serious complication in patients with spontaneous intracerebral hemorrhage (SICH), contributing to prolonged hospital stays poor outcomes. Nutritional status has been linked the development of SAP ischemic stroke, but its role SICH remains understudied. This study aims evaluate predictive value Risk Screening-2002 (NRS-2002) score for compare it other nutritional assessment tools. Methods retrospective observational included 404...
Entacapone has been widely used in the treatment of moderate to advanced Parkinson's disease (PD), and its efficacy for motor symptoms well-known from several clinical trials long-term use. The Levodopa/Carbidopa/Entacapone (LCE) on neuropsychological functions PD not validated yet, little is known about effect LCE peripheral inflammatory cytokines. aim this study was investigate explore relationship with changes cytokine levels. All patients were randomly assigned experimental group...
Performances of the Acute Physiology and Chronic Health Evaluation II (APACHE II) score Sequential Organ Failure Assessment (SOFA) were assessed in predicting mortality outcome critically ill elderly patients.Mean APACHE SOFA scores compared 106 intensive care unit patients aged > 65 years classified as survivors or deaths. The discriminatory ability was evaluated using area under receiver operating characteristic (ROC) curve. Calibration Hosmer-Lemeshow test.Mean lower than those who died....
There is accumulating evidence that gut microbiota plays a key role in cardiovascular diseases. Gut bacteria can transform dietary choline, l-carnitine, and trimethylamine N-oxide (TMAO) into trimethylamine, which be oxidized TMAO again the liver. However, alterations of large artery atherosclerotic (LAA) stroke cardioembolic (CE) have been less studied.We performed case-control study patients with LAA CE types strokes. We profiled microbiome using Illumina sequencing 16S ribosomal RNA gene...
Background and purpose Initiation of early antiplatelet (EA) therapy after acute ischaemic stroke (AIS) is essential. We aimed to investigate the safety effectiveness EA in patients who had an AIS with haemorrhagic infarction (HI) intravenous thrombolysis (IVT). Methods Based on a multicentre registry database, post-thrombolysis HI at 24 hours were identified. users non-EA defined as received or did not receive between 48 IVT. Primary outcome was favourable modified Rankin Scale scores 0–2 3...
There is scant evidence regarding the safety of antiplatelet therapy in acute ischemic stroke (AIS) patients with thrombocytopenia. Our study aims to address this concern by examining AIS thrombocytopenia from a large database real-world settings.
Objective. The role of trimethylamine N-oxide (TMAO) in cardiovascular diseases has been highlighted. Nevertheless, the associations large-artery atherosclerotic (LAA) stroke with TMAO and blood lipid-related indices are little investigated. Methods. A cross-sectional comparative study was performed on 50 patients LAA healthy controls. Basic demographic data, common vascular risk factors, were collected. Plasma detected through liquid chromatography tandem mass spectrometry. Multivariable...
Objective. Psychological status plays a vital role in the recovery young ischemic stroke patients. However, few reports on psychological symptoms Chinese patients have been published. In present study, we aimed to outline of and its risk factors at three months after their stroke. Methods. 364 with 384 age‐matched healthy controls were consecutively recruited from our study hospitals mainland China between June 2018 November 2020. Social demographic clinical data collected all enrolled...
This study aimed to investigate the association between atrial fibrillation (AF), particularly newly diagnosed AF, and remote intracerebral hemorrhage (rICH) in patients with ischemic stroke who were treated intravenous thrombolysis (IVT). observational was conducted on received IVT recombinant tissue-type plasminogen activator. The data taken from a multicenter prospective registry of Chinese population. rICH defined as any extraischemic detected computerized tomography (CT) 24 h after...
Abstract Background — With the establishment of concept gut–brain axis, increasing evidence has shown that gut microbiome plays an important role in pathogenesis cardiovascular diseases. Gut bacteria can transform dietary choline, L-carnitine, and trimethylamine N -oxide (TMAO) into trimethylamine, which be oxidized TMAO again liver participate atherogenesis. However, only few studies have described alterations microbiota composition function cardioembolic (CE) large artery atherosclerotic...
To investigate the safety of early antiplatelet therapy for non-cardioembolic mild stroke patients with thrombocytopenia.
Background and aim Symptomatic intracranial hemorrhage (sICH) was the most serious complication associated with alteplase intravenous thrombolysis (IVT) in acute ischemic stroke (AIS) patients. However, relationship between serum sodium levels post-thrombolysis symptomatic has not been investigated. Therefore, of this study to investigate pre-thrombolysis sICH after IVT, as well explore optimal for lowering risk following IVT. Methods From July 1, 2017 April 30, 2023, out-of-hospital AIS...
心肌梗死后早期接受心脏康复治疗可改善心室重构，但对于心肌梗死多年的患者，通过心脏康复治疗改善左心室重构，提升左心室射血分数的报道极少。该文报道1例前壁心肌梗死冠状动脉介入治疗术后10年左心室扩大、射血分数降低的患者，通过居家心脏康复治疗左心室功能明显改善的过程，包括心脏康复评估、运动风险把控、制定及调整运动处方、更新药物处方、提供营养心理建议和戒烟指导等，以期为临床上此类患者的康复治疗提供参考。.
Objective To analyze the geographic variation in characteristics and treatment processes of patients with acute ischemic stroke (AIS) coastal, island, inland regions. Methods We conducted a retrospective, cross-sectional analysis data from AIS southeastern China. collected demographic clinical information, including time onset to for those receiving reperfusion therapy, using time-tracking table. Results Among 8069 AIS, 26.6% received higher proportion undergoing endovascular therapy...
This study aimed to develop a predictive model for early neurological deterioration (END) in branch atheromatous disease (BAD) affecting the lenticulostriate artery (LSA) territory using machine learning. Additionally, it explore underlying mechanisms of END occurrence this context.
To investigate the effect of treatment time on outcome patients with ischemic stroke undergoing reperfusion therapy.The clinical data 3229 who received intravenous thrombolysis or without arterial from 71 hospitals in Zhejiang province June 2017 to September 2018 were retrospectively reviewed. The good was defined as modified Rankin Scale (mRS) ≤ 2. Binary logistic regression analysis used association door needle (DNT), (DRT) outcomes treated by bridging thrombolysis, respectively.Binary...
This study aimed to create and validate a novel nomogram predict the risk of symptomatic intracranial hemorrhage (sICH) in patients with acute ischemic stroke (AIS) who underwent intravenous thrombolysis (IVT).In this retrospective study, 784 AIS received IVT were enrolled. The randomly divided into two groups: training set (n=550, 70%) testing (n=234, 30%). Utilizing multivariable logistic regression analysis, relevant factors for predictive selected. performance was evaluated using various...
To compare the time delay between in-hospital stroke and out-of-hospital patients, to explore influence factors for prognosis of patients treated by intravenous thrombolysis.Clinical data 3050 with ischemic who received thrombolysis in 71 hospitals Zhejiang province from June 2017 September 2018 were analyzed. Differences including door imaging (DIT), needle (INT) (DNT) (n=101) (n=2949) observed. The influencing outcome at 3 month after analyzed using binary logistic regression...