A5034236628- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Hepatitis B Virus Studies
- Transplantation: Methods and Outcomes
- Liver physiology and pathology
- Renal Transplantation Outcomes and Treatments
- Minimally Invasive Surgical Techniques
- Hepatitis C virus research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Viral-associated cancers and disorders
- Organ Donation and Transplantation
- Cancer, Lipids, and Metabolism
- Gastrointestinal Tumor Research and Treatment
- Gastric Cancer Management and Outcomes
- Endoplasmic Reticulum Stress and Disease
- Congenital Anomalies and Fetal Surgery
- Gastrointestinal disorders and treatments
- Multiple and Secondary Primary Cancers
- Intestinal Malrotation and Obstruction Disorders
- Acute Kidney Injury Research
- Blood groups and transfusion
Catholic University of Korea
2014-2024
Bucheon St. Mary's Hospital
2017-2024
Seoul St. Mary's Hospital
2011-2019
The purpose of this study was to evaluate the feasibility living donor liver transplantation for treatment patients with hepatocellular carcinoma and segmental portal vein tumor thrombus (PVTT) below second‐order branch. Between January 2005 December 2015, we retrospectively analyzed 242 in a control group (n = 184), microvascular invasion (MVI) 24), PVTT 34). To assess risks associated PVTT, evaluated recurrence, disease‐free survival (DFS) rate, overall (OS) various other factors based on...
To investigate that inflammatory markers can predict accurately the prognosis of hepatocelluar carcinoma (HCC) patients in living-donor liver transplantation (LDLT).From October 2000 to November 2011, 224 who underwent living donor for HCC at our institution were enrolled this study. We analyzed disease-free survival (DFS) and overall (OS) after LT with designed a new score model using pretransplant neutrophil-lymphocyte ratio (NLR) C-reactive protein (CRP).The DFS OS an NLR level ≥ 6.0 or...
Purpose: Pancreaticoduodenectomy (PD) is the treatment of choice for periampullary disease. Even with increasing number successful reports from around globe, laparoscopic pancreaticoduodenectomy (LPD) still not fully accepted. We report results our experience LPD assisted by mini-laparotomy. Method: This retrospective review study included 42 patients who received mini-laparotomy between March 2009 and April 2012. Clinical outcomes, such as patient age, pathologic diagnosis, pancreas nature,...
Purpose: Living donor liver transplantation (LDLT) using elderly donors is increasing in frequency response to organ shortage.However, graft has been reported negatively affect patency and patient survival.Methods: We retrospectively reviewed the medical records of 604 patients who underwent LDLT at Seoul St. Mary's Hospital, The Catholic University Korea between May 1999 September 2012.Elderly were defined as those ≥55 years age.Here, we evaluate survival differences causes death recipients...
AIM:To evaluated patterns and outcomes of hepatocellular carcinoma (HCC) recurrence after living donor liver transplantation (LDLT). METHODS:From 2001 to 2014, 293 patients underwent LDLT for HCC at our transplant center.We retrospectively reviewed 54 (18.4%) with LDLT.We LDLT, particular attention the Milan criteria transplantation, treatments HCC-recurrent patients, factors related survival recurrence.Furthermore, we efficacy combination treatment sorafenib an mTOR inhibitor. RESULTS:The...
Laparoscopic spleen-preserving distal pancreatectomy has been widely performed for benign and borderline malignancy in the body or tail of pancreas when there are not oncologic indications splenectomy. As need minimally invasive procedures to reduce postoperative morbidity improve quality life is increasing, many surgeons have attempted number trocars incision size minimize access trauma scarring. Single-port laparoscopic result these efforts; however it limitations such as technical...
Liver fibrosis is a critical health issue with limited treatment options. This study investigates the potential of PGC-Sec, secretome derived from peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α)-overexpressing adipose-derived stem cells (ASCs), as novel therapeutic strategy for liver fibrosis.
BACKGROUND The aim of this study was to define the best curative strategy in patients with hepatocellular carcinoma (HCC) a hepatitis B virus (HBV)-endemic region where living donation dominates type cadaveric for liver transplantation (LT). MATERIAL AND METHODS A retrospective cohort comprised those whose clinical course could potentially be traced at least 10 years. We found 262 HCC who had undergone surgical treatment from March 1997 August 2006. Among these patients, 156 were treated...
Abstract The epidemiology of invasive fungal infections (IFIs) after liver transplantation (LT) is continuing to evolve in the current era antifungal prophylactic therapy. This multicenter retrospective cohort study aimed evaluate epidemiology, risk factors, and outcomes IFIs among LT recipients era. We analyzed a total 482 aged 18 years older who were admitted 3 tertiary hospitals Korea between January 2009 February 2012. Twenty-four episodes occurred 23 patients (4.77%; 23/482). Of these...
The anticancer effect of statins is drawing attention. However, it unclear whether statin use reduces the risk hepatocellular carcinoma (HCC) recurrence in patients who undergo liver transplantation (LT) for HCC. Consecutive underwent LT HCC between 1995 and 2019 were enrolled. effects on mortality compared user nonuser groups. We performed analyses a variety ways, including inverse probability treatment weighting (IPTW) methods to balance any confounders landmark method avoid immortal time...
Without effective prophylaxis, liver transplantation (LT) for hepatitis B virus (HBV)-related disease is frequently complicated by severe and rapidly progressive HBV recurrence. The combination of low-dose immunoglobulin (HBIG) the new nucleos(t)ide analog, entecavir, as prophylaxis recurrence after living-donor LT (LDLT) were analyzed.A total 315 patients with positive surface antigen underwent LDLT at our transplant center between July 2003 December 2011. Our protocol post-transplantation...
The use of hepatitis B core antibody (HBcAb)-positive grafts is increasing, especially where endemic. However, this remains controversial because the risk development de novo HBV infection.We collected information obtained between January 2000 and December 2012 retrospectively analyzed data on 187 HBsAg-negative donors recipients were retrospectively. De infection was defined as HBsAg positivity with or without detection DNA.Forty patients (21.4%) received HBcAb-positive grafts. Survival...
Single-port laparoscopic splenectomy has been performed sporadically. The aim of this study is to assess our experience with single-port compared conventional multiport surgery for the usual treatment modality various kinds splenic disease.Between October 2008 February 2014, 29 patients underwent and 32 received splenectomy. We retrospectively analyzed clinical outcomes group group.The body mass index disease profiles both groups were similar. operative times 113.6 ± 39.9 95.9 38.9 minutes,...
The liver is a central organ for the metabolism of iron and manganese places where those metals are commonly deposited overlap in brain.To elucidate relationship between pallidal T1 hyperintensity deposition deep gray matter cirrhosis patients using quantitative susceptibility mapping (QSM).Retrospective case-control study SUBJECTS: In all, 38 consecutive who received brain magnetic resonance imaging (MRI) as pretransplant evaluation.QSM was reconstructed from 3D multi- or single-echo phase...
Purpose: The aim of the current study was to directly investigate whether active gas suction reduces intraperitoneal residual carbon dioxide and analyze effect on postoperative pain after laparoscopic cholecystectomy. Subjects Methods: This prospective, randomized clinical included patients between 19 65 years age with gallbladder disease who were eligible for elective Patients allocated into either natural evacuation group (NE group) or (AS group). In AS group, applied by inserting...
The interaction between killer immunoglobulin-like receptors (KIRs) and HLA class I regulates natural (NK) cell cytotoxicity function. impact of NK alloreactivity through KIR in liver transplantation remains unelucidated. Since the frequency HLA-C genotypes show ethnic differences, we assessed HLA-C, genotype, or KIR-ligand mismatch on allograft outcome Korean allografts.One hundred eighty-two living donor transplant patients were studied. Thirty-five (19.2%) had biopsy-confirmed acute...
BACKGROUND We evaluated the effects of preoperative positive cross-match and HLA mismatching on early acute cellular rejection graft survival in living donor liver transplantation (LDLT). MATERIAL AND METHODS retrospectively reviewed data 286 patients who underwent LDLT from 2008 to 2013. Cross-matching tests were performed by complement-dependent lymphocytotoxicity (CDC) flow cytometry (FCX) methods. The CDC cross-matching test was using National Institutes Health (NIH) standard...
Although methyl-tertiary butyl ether (MTBE) is the only clinical topical agent for gallstone dissolution, its use limited by side effects mostly arising from a relatively low boiling point (55 °C). In this study, we developed gallstone-dissolving compound containing an aromatic moiety, named 2-methoxy-6-methylpyridine (MMP) with higher (156 °C), and compared effectiveness toxicities MTBE.The dissolubility of MTBE MMP in vitro was determined placing human gallstones glass containers either...
To evaluate the surgical outcomes of pancreaticogastrostomy (PG) using two transpancreatic sutures with a buttress method through an anterior gastrostomy (PGt), and compare these results our previous experience pancreaticojejunostomy (PJ) including dunking duct to mucosa methods after pancreaticoduodenectomy (PD).In this study, 171 patients who had undergone PD between January 2005 April 2013 were classified into three groups according pancreaticoenteric anastomosis: PJ (PJu group; n = 67,...
Purpose: To determine the optimum culture conditions by investigating isolated rat hepatocytes cultured in medium containing different glucose concentrations.Methods: Hepatocytes were from rats using a two-step perfusion technique and divided into following two groups concentrations: (1) low-glucose group (2) high-glucose group.Total cell count viability of liver function parameters (i.e., concentrations albumin, ammonia, urea medium) measured.The morphology was examined staining with...