Zheng Li

ORCID: 0000-0002-3188-8300
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About
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Research Areas
  • Plant Molecular Biology Research
  • Plant Reproductive Biology
  • Advances in Cucurbitaceae Research
  • Plant Virus Research Studies
  • Photosynthetic Processes and Mechanisms
  • Cocoa and Sweet Potato Agronomy
  • Plant Gene Expression Analysis
  • Chromosomal and Genetic Variations
  • Plant nutrient uptake and metabolism
  • Genomics and Phylogenetic Studies
  • Connexins and lens biology
  • Plant Stress Responses and Tolerance
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Fungal and yeast genetics research
  • Plant tissue culture and regeneration
  • Genomics and Chromatin Dynamics
  • Genomic variations and chromosomal abnormalities
  • Molecular Biology Techniques and Applications
  • Heat shock proteins research
  • Polysaccharides and Plant Cell Walls
  • Light effects on plants
  • Cancer-related gene regulation
  • Legume Nitrogen Fixing Symbiosis
  • Developmental Biology and Gene Regulation
  • Mycorrhizal Fungi and Plant Interactions

Shenyang Agricultural University
2025

Guangxi Medical University
2025

Northwest A&F University
2013-2024

Beijing Forestry University
2022-2024

Yunnan University
2023-2024

Ministry of Agriculture and Rural Affairs
2024

University of Nebraska Medical Center
2016-2023

Shanghai Jiao Tong University
2009-2023

Henan University
2017-2023

University of California, Los Angeles
2022-2023

Cisplatin (CDDP) treatment is one of the most predominant chemotherapeutic strategies for patients with gastric cancer (GC). A better understanding mechanisms CDDP resistance can greatly improve therapeutic efficacy in GC. Circular RNAs (circRNAs) are a class noncoding whose functions related to pathogenesis cancer, but, GC remains unknown. circAKT3 (hsa_circ_0000199, circRNA originating from exons 8, 9, 10, and 11 AKT3 gene) was identified by RNA sequencing verified quantitative reverse...

10.1186/s12943-019-0969-3 article EN cc-by Molecular Cancer 2019-03-30

Significance Polyploidy or whole genome duplication (WGD) is considered a major force in plant evolution, but less important animals. The most diverse group of animals, the insects, are thought to have evolved without ever experiencing WGD. Our analyses genomic data found evidence for 18 ancient WGDs and at least six other bursts gene during evolution insects. Further, we that functional patterns retention loss these insect genomes consistent with signatures WGDs. expanding collection...

10.1073/pnas.1710791115 article EN public-domain Proceedings of the National Academy of Sciences 2018-04-19

Sex determination in plants involves a variety of mechanisms. Here, we report the map-based cloning and characterization unisexual-flower-controlling gene M. M was identified as previously characterized putative 1-aminocyclopropane-1-carboxylic acid synthase gene, while m allele that mutated at conserved site (Gly33Cys) lost activity original enzymatically active allele.

10.1534/genetics.109.104737 article EN Genetics 2009-05-28

Hybridization and polyploidy followed by genome-wide diploidization had a significant impact on the diversification of land plants. The ancient At-α whole-genome duplication (WGD) preceded crucifers (Brassicaceae). Some genera tribes also experienced younger, mesopolyploid WGDs concealed subsequent genome diploidization. Here we tested if multiple base chromosome numbers originated due to after independent how affected post-polyploid gene retention. Sixteen species representing 10...

10.1111/tpj.13553 article EN The Plant Journal 2017-04-03

It is well established that the plant hormone ethylene plays a key role in cucumber sex determination. Since unisexual control gene M was cloned and shown to encode an synthase, instead of receptor, 'one-hormone hypothesis', which used explain phenotype, has been challenged. Here, physiological function CsACS2 (the encoded by locus) studied using transgenic tobacco system. The results indicated overexpression increased production plant, native promoter had no activity (PM). However, when PM...

10.1093/jxb/ers123 article EN cc-by-nc Journal of Experimental Botany 2012-05-10

Host RNA-dependent RNA polymerases (RDRs) 1 and 6 contribute to antiviral silencing in plants. RDR6 is constitutively expressed was previously shown limit invasion of Nicotiana benthamiana meristem tissue by potato virus X thereby inhibit disease development. RDR1 inducible salicylic acid (SA) several other phytohormones. But although it contributes basal resistance tobacco mosaic (TMV) dispensable for SA-induced inoculated leaves. The laboratory accession N. a natural rdr1 mutant highly...

10.1186/s12870-016-0705-8 article EN cc-by BMC Plant Biology 2016-01-13

The microrchidia (MORC) proteins are a family of evolutionarily conserved GHKL-type ATPases involved in chromatin compaction and gene silencing. Arabidopsis MORC act the RNA-directed DNA methylation (RdDM) pathway, where they as molecular tethers to ensure efficient establishment RdDM de novo However, also have RdDM-independent functions although their underlying mechanisms unknown.

10.1186/s13059-023-02939-4 article EN cc-by Genome biology 2023-04-26

In plants, unisexual flowers derived from developmental sex determination form separate stamens and pistils that facilitate cross pollination. cucumber melon, ethylene plays a key role in determination. Six determination-related genes have been identified biosynthesis these Cucumis species. The interactions among are thought to involve signaling; however, the underlying mechanism of regulation remains unknown. this study, hormone treatment qPCR assays were used confirm expression melon is...

10.1093/jxb/ery128 article EN Journal of Experimental Botany 2018-04-03

Plant cell walls are essential for plant growth and development. The traditionally divided into primary walls, which surround growing cells, secondary provide structural support to certain types promote their functions. While much information is available about the enzymes components that contribute production of these two less known transition from wall synthesis. To address this question, we made use a transcription factor system in Arabidopsis (Arabidopsis thaliana) an overexpressed...

10.1104/pp.16.01100 article EN PLANT PHYSIOLOGY 2016-08-26

Summary Anther and ovule genesis preconditions crop fertilization fruit production; however, coordinative regulation of anther development underlying molecular pathways remain largely elusive. Here, we found that SPOROCYTELESS ( SPL )/ NOZZLE NZZ ) expression was nearly abolished in a Cucumis sativus (cucumber) mutant with severely defective development. Cs expressed specifically the developing anthers ovules. Knock‐down reduced male female fertility malformed pollen suppressed Importantly,...

10.1111/tpj.13877 article EN The Plant Journal 2018-02-23

The WUSCHEL-related homeobox (WOX) is a family of plant-specific transcription factors, with important functions, such as regulating the dynamic balance division and differentiation plant stem cells organ development. We identified 14 distinct TaWOX genes in wheat (Triticum aestivum L.) genome, based on genome-wide scan approach. All under evaluation had positional homoeologs subgenomes A, B D except TaWUS TaWOX14. Both TaWOX14a TaWOX14d paralogous copy same genome due to tandem duplication...

10.3390/ijms21051581 article EN International Journal of Molecular Sciences 2020-02-26

Abstract Unisexual flowers provide a useful system for studying plant sex determination. In cucumber (Cucumis sativus L.), three major Mendelian loci control unisexual flower development, Female (F), androecious [a; 1-aminocyclopropane-1-carboxylate {ACC} synthase 11, acs11], and Monoecious (M; ACS2), referred to here as the Female, Androecious, (FAM) model, in combination with two genes, gynoecious (g, WIP family C2H2 zinc finger transcription factor gene WIP1) ethylene biosynthetic ACC...

10.1093/plcell/koaa018 article EN cc-by-nc-nd The Plant Cell 2020-12-02

The two homologous genes, NIA1 and NIA2, encode nitrate reductases in Arabidopsis, which govern the reduction of to nitrite. This step is rate-limiting assimilation utilization. Therefore, regulation NIA2 important for plant development growth. Although they are similar sequence structure, their regulations different. Genetic analysis uncovers that NIA1, rather than plays a predominant role adopting ABA stress. both long-term stress conditions can cause an improvement levels, decrease levels...

10.3390/ijms23031202 article EN International Journal of Molecular Sciences 2022-01-21

Abstract Light signals promote photomorphogenesis and photosynthesis, allowing plants to establish photoautotrophic growth. Chloroplasts are organelles responsible for photosynthesis in which light energy is converted into chemical stored as organic matter. However, how regulates chloroplast remains unclear. Here, we isolated a cucumber (Cucumis sativus L.) mutant albino seedling (as) from an ethyl methane sulfonate mutagenesis library with phenotype. Map-based cloning revealed that the...

10.1093/plphys/kiad296 article EN PLANT PHYSIOLOGY 2023-05-22

Summary Rhizomes are modified stems that grow underground and produce new individuals genetically identical to the mother plant. Recently, a breakthrough has been made in efforts convert annual grains into perennial ones by utilizing wild rhizomatous species as donors, yet developmental biology of this organ is rarely studied. Oryza longistaminata , rice featuring strong rhizomes, provides valuable model for exploration rhizome development. Here, we first assembled double‐haplotype genome O....

10.1111/pbi.14294 article EN cc-by-nc-nd Plant Biotechnology Journal 2024-02-12

Abstract Cucumber (Cucumis sativus, Cs) tendrils are slender vegetative organs that typically require manual removal to ensure orderly growth during greenhouse cultivation. Here, we identified cucumber tendril-less (tl), a Tnt1 retrotransposon-induced insertion mutant lacking tendrils. Map-based cloning the mutated gene, CsaV3_3G003590, which designated as CsTL, is homologous Arabidopsis thaliana LATERAL SUPPRESSOR (AtLAS). Knocking out CsTL repressed tendril formation but did not affect...

10.1093/plcell/koae123 article EN The Plant Cell 2024-04-17

We present a method for detecting evidence of natural selection in ancient DNA time-series data that leverages an opportunity not utilized previous scans: testing consistent trend allele frequency change over time. By applying this to 8433 West Eurasians who lived the past 14000 years and 6510 contemporary people, we find order magnitude more genome-wide significant signals than studies: 347 independent loci with >99% probability selection. Previous work showed classic hard sweeps driving...

10.1101/2024.09.14.613021 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-09-15

Abstract Osteoblasts play a critical role in maintaining bone homeostasis. Senescence causes by free radical-mediated oxidative stress may affect the viability and osteogenic differentiation potential of osteoblast during formation. To eliminate impacts senescent cells radical scavenging is an optimal option for regeneration age-related disease, such as osteoporosis (OP) periodontitis. In this study, we fabricated antioxidant film (CG-ARB) crosslinking chitosan (C) gelatin (G) using...

10.1088/1748-605x/adae6d article EN Biomedical Materials 2025-01-24

In the field of conservation tillage, no-till seeding technology has emerged as an efficient and environmentally friendly form agricultural production. It is increasingly recognized a crucial avenue toward sustainable development. This study focuses on research technology, specifically analyzing technical characteristics seeders, their principles operation, application. No-till planters are designed to either minimize or eliminate soil tillage. When paired with precision they can...

10.3390/su17051808 article EN Sustainability 2025-02-20
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