A5101781278- Renal cell carcinoma treatment
- Renal and related cancers
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Ferroptosis and cancer prognosis
- Urinary and Genital Oncology Studies
- Cancer-related molecular mechanisms research
- Musculoskeletal pain and rehabilitation
- Refrigeration and Air Conditioning Technologies
- Cancer, Lipids, and Metabolism
- RNA modifications and cancer
- MRI in cancer diagnosis
- Multiple and Secondary Primary Cancers
- Cancer Genomics and Diagnostics
- Prostate Cancer Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Tuberous Sclerosis Complex Research
- Urologic and reproductive health conditions
- MicroRNA in disease regulation
- Radiopharmaceutical Chemistry and Applications
- Cancer Treatment and Pharmacology
- Thermodynamic and Exergetic Analyses of Power and Cooling Systems
- Hemophilia Treatment and Research
- Cancer Immunotherapy and Biomarkers
- Urological Disorders and Treatments
Sun Yat-sen University
2002-2025
Sun Yat-sen University Cancer Center
2002-2025
Southern University of Science and Technology
2021-2025
Tianjin Chest Hospital
2019-2025
University of Electronic Science and Technology of China
2024-2025
Tianjin University
2025
Southeast University
2023-2024
First Affiliated Hospital of Xinxiang Medical University
2018-2024
Peking University
2019-2023
Peking University Third Hospital
2019-2023
Abstract Thermal energy storage technologies based on phase‐change materials (PCMs) have received tremendous attention in recent years. These are capable of reversibly storing large amounts thermal during the isothermal phase transition and offer enormous potential development state‐of‐the‐art renewable infrastructure. conductivity plays a vital role regulating charging discharging rate PCMs improving heat‐utilization efficiency. The strategies for tuning their applications, such as...
The potentiation of antibiotics is a promising strategy for combatting antibiotic-resistant/tolerant bacteria. Herein, we report that 5-min sublethal heat shock enhances the bactericidal actions aminoglycoside by six orders magnitude against both exponential- and stationary-phase Escherichia coli . This combined treatment also effectively kills various E. persisters, clinical isolates, numerous gram-negative but not gram-positive bacteria enables aminoglycosides at 5% minimum inhibitory...
To explore the clinical features and genetic characteristics of three patients with Infantile liver failure syndrome type 2 (ILFS2). Three children who were diagnosed ILFS2 at Children's Hospital Affiliated to Zhengzhou University from February 2023 2024 selected as study subjects. Clinical data collected. Peripheral blood samples their parents collected subjected whole exome sequencing (WES). Candidate variants NBAS gene verified by Sanger sequencing. This was approved Ethics Committee...
Background Nicotinamide (NAM) metabolism fulfills crucial functions in tumor progression. The present study aims to establish a NAM metabolism-correlated gene (NMRG) signature assess the immunotherapy response and prognosis of lung adenocarcinoma (LUAD). Methods training set validation (the GSE31210 dataset) were collected Cancer Genome Atlas (TCGA) Gene Expression Omnibus (GEO), respectively. Molecular subtypes LUAD classified by consensus clustering. Mutation landscape top 20 somatic genes...
Introduction Tumor-infiltrating B lymphocytes (TILBs) play a pivotal role in shaping the immune microenvironment of tumors (TIME) and progression lung adenocarcinoma (LUAD). However, there remains scarcity research that has thoroughly systematically delineated characteristics TILBs LUAD. Method The employed single-cell RNA sequencing from GSE117570 dataset to identify markers linked TILBs. A comprehensive machine learning approach, utilizing ten distinct algorithms, facilitated creation...
BACKGROUND:Metastasis contributes to the high mortality rate of non-small cell lung cancer (NSCLC), and gaining a better understanding its metastatic mechanisms would aid in initiating effective clinical treatment. MATERIAL AND METHODS:In this study, bioinformatics analyses GEO database TCGA-LUAD were first used identify key node gene regulating NSCLC malignant progression. Further vitro experiments, including wound healing assay, invasion Western blot luciferase report clarify functions...
In this work, the potential use of nanoparticles as contrast agents by using spectral domain optical coherence tomography (SD-OCT) in liver tissue was demonstrated. Gold (average size 25 and 70 nm), were studied human normal cancerous tissues vitro, respectively. Each sample monitored with SD-OCT functional imaging for 240 min. Continuous OCT monitoring showed that, after application gold nanoparticles, signal intensities both increase time, larger tend to produce a greater enhancement same...
Abstract Piwi proteins and their partner small RNAs play an essential role in fertility, germ-line stem cell development, the basic control evolution of animal genomes. However, little knowledge exists regarding piRNA biogenesis. Utilizing microfluidic chip analysis, we present a quantitative profile zebrafish piRNAs expressed differentially between testis ovary. The sex-specific are derived from separate loci repeat elements genome. Ovarian can be categorized into groups that reach up to 92...
Objective To analyze the epidemiology information of prostate cancer from three centers Bejing,Shanghai,Guangzhou,and to reflect current situation in China,and 272 patients with advanced who received hormonal therapy find prognostic factors hormone therapy.Methods Collect 525 centers.Two hundred and seventy-two cases full were selected therapy.Results Three fifty-seven cases(68.0%)had disease at diagnosis 80.2% as main therapy.Prognostic analysis indicared that Gleason score, bone metastasis...
// Zhi Yong Li 1, 2, 3, * , Xin Xiang Fan 4, Yan Jun Wang Kai Yao 3 Zhuo Wei Liu Wen Tao Pan Yun Lin Ye Ping Yang Yi Chuan Huang 4 Ming Wu Fang Jian Zhou 1 State Key Laboratory of Oncology in Southern China, Guangzhou, China 2 Department Urology, Sun Yat-Sen University Cancer Center, Collaborative Innovation Center for Medicine, Memorial Hospital, These authors contributed equally to this work Correspondence to: Wu, email: wuzhim@sysucc.org.cn Zhou, zhoufj@sysucc.org.cn Keywords: RCC,...
Through the investigation of difference approximate entropy (ApEn) and Hilbert-Huang Transform Marginal spectrum (HHTMSEn) Electroencephalogram (EEG) signals specific low back pain (SLBP) patients before after massage, we wanted to reveal impact massage in brain, provided basis for treatment SLBP patients. We recruited twenty-six collected their spontaneous EEG massage. Firstly, analyzed ApEn HHTMSEn fourteen channels results showed that values were less than significantly. And then,...
This study aimed to identify physiological and pharmacogenomic covariates develop a population pharmacokinetic model of high-dose methotrexate (HD-MTX) in Chinese paediatric patients with acute lymphoblastic leukaemia (ALL) malignant lymphoma.A total 731 MTX courses 1658 plasm concentrations from 205 ALL lymphoma were analysing using non-linear mixed-effects technique. 47 SNPs 16 MTX-related genes genotyped screened as covariates. A PPK was established determine the influence covariates,...
Background. The majority of lung cancers are adenocarcinomas, with the proportion being 40%. patients mostly diagnosed in middle and late stages metastasis easy recurrence, which poses great challenge to treatment prognosis. Platinum-based chemotherapy is a primary for adenocarcinoma, frequently causes drug resistance. As result, it important uncover mechanisms chemoresponse adenocarcinoma platinum-based chemotherapy. Methods. genes from dataset GSE7880 were gathered into gene modules...
Abstract Background Intra-articular bleeds in patients with inherited bleeding disorders lead to active synovitis which may progress a chronic state over time. We explored the diagnostic value of color Doppler ultrasound detecting boys disorders. Results Sixty hemophilia and 3 type von Willebrand disease aged 5 18 years (median 12.3 years) were imaged by gray-scale (US) three centers (Beijing, China [ n = 22], Guangzhou, 12] Toronto, Canada 29])) this observational study. Images...
Graphene oxide nanosheet (NGO) was covalently functionalized with positively charged, branched polyethylenimine (bPEI) via an amide bond, coated serum proteins by electrostatic interaction. Operating as a newly fashioned, multifunctional nanocarrier, the processed NGO showed promise for use in combined gene therapy, chemotherapy, photothermal bioimaging and biosensor of cancer cells. Our current research is focused on systematic studies mechanisms cellular uptake, subcellular location,...