A5028120189- Dementia and Cognitive Impairment Research
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- COVID-19 and Mental Health
- COVID-19 and healthcare impacts
- Frailty in Older Adults
- Nutritional Studies and Diet
- Hemoglobinopathies and Related Disorders
- Acute Myeloid Leukemia Research
- COVID-19 epidemiological studies
- Schizophrenia research and treatment
- Pharmaceutical Practices and Patient Outcomes
- Iron Metabolism and Disorders
- Stroke Rehabilitation and Recovery
- Treatment of Major Depression
- Traumatic Brain Injury Research
- Intensive Care Unit Cognitive Disorders
- Multiple Myeloma Research and Treatments
- Amyotrophic Lateral Sclerosis Research
- Cardiovascular Issues in Pregnancy
- Genetics, Aging, and Longevity in Model Organisms
- Potassium and Related Disorders
- Bipolar Disorder and Treatment
- COVID-19 Digital Contact Tracing
Mario Negri Institute for Pharmacological Research
2018-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2024
Regione Lombardia
2023
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2021-2023
Lombardia Informatica (Italy)
2023
ORCID
2023
Institute for Transfusion Medicine
2021
University Orthopedics Center
2021
University of Milano-Bicocca
2006-2018
Abstract Aim To longitudinally describe stroke caregivers’ quality of life, anxiety, depression and burden to identify predictors burden. Background Caregivers have a key role in survivor care the first year caregiving is most challenging. give tailored interventions, it important capture changes caregiver during year. Design A 12‐month longitudinal study. Data were collected between June 2013–May 2016. Methods Changes anxiety their identified using linear mixed‐effects models. Results The...
Our knowledge on the long-term consequences of COVID-19 is still scarce despite clinical relevance persisting syndrome. The aim this study was to analyze patient-reported outcomes, including assessment by specific questionnaires health impairment and symptoms.This a prospective, observational multicenter cohort coordinated Fondazione IRCSS Ca' Granda Ospedale Maggiore Policlinico di Milano Istituto Ricerche Farmacologiche Mario Negri IRCCS eight hospitals located in North Central Italy. A...
Abstract Background Lombardy was affected in the early months of 2020 by SARS‐CoV‐2 pandemic with very high morbidity and mortality. The post‐COVID‐19 condition related public health burden are scarcely known. Setting design Using regional population administrative database including all 48,932 individuals who survived COVID‐19 became polymerase‐chain‐reaction negative for 31 May 2020, incident mortality, rehospitalizations, attendances to hospital emergency room, outpatient medical visits...
Abstract Background Functional decline (decrement in physical/cognitive functioning that causes inability to engage daily activities) is common following acute hospitalization elderly patients and associated with hospital readmission, institutionalization, mortality. We sought determine rate of institutionalization after COVID-19 characterize functional institutionalized COVID-19. Characteristics pre-COVID-19 hospitalized Methods conducted a retrospective cohort study using health...
Abstract Introduction Relationship between age and dementia at extreme old ages is still an open question, yet population‐based studies in this high‐risk segment are rare. Methods The Monzino 80‐plus a study among residents 80 years older the Varese province, Italy. Of 1371 eligible individuals, 1294 (94.4%), of whom 64 centenarians, were included incidence study. Results Since 2002, 584 new cases all‐cause identified over 15 years. overall rate was 7.9 per 100 person‐years. Dementia risk...
Chronic obstructive pulmonary disease (COPD) and heart failure (HF) mutually increase the risk of being present in same patient, especially if older. Whether or not this coexistence may be associated with a worse prognosis is debated. Therefore, employing data derived from REPOSI register, we evaluated clinical features outcomes population elderly patients admitted to internal medicine wards having COPD, HF COPD + HF.We measured socio-demographic anthropometric characteristics, severity...
Differences in survival between patients treated with antipsychotic monotherapy vs. polytherapy are debated. This study aimed to examine the association of 2-year all-cause mortality a population-based cohort.
Monoclonal gammopathy of undetermined significance (MGUS) and clonal hematopoiesis (CH) are 2 preclinical expansions hematopoietic cells whose prevalence rises with age, reaching almost 10% in people aged 70 years older. The increased risk myeloid malignancies patients myeloma is well defined, the study association between CH MGUS could help explain this phenomenon. Here, we analyzed a fully clinically annotated dataset 777 older subjects (median 91 years) previously screened for CH. was...
Abstract Background Neuropsychological testing plays a cardinal role in the diagnosis and monitoring of Alzheimer’s disease. A major concern is represented by heterogeneity neuropsychological batteries currently adopted memory clinics healthcare centers. The current study aimed to solve this issue. Methods Following initiative University Washington’s National Coordinating Center (NACC), we presented Italian adaptation Test Battery Uniform Data Set (I-UDSNB). We collected data from 433...
Background Mild anemia is a frequent although often overlooked finding in old age. Nevertheless, recent years has been linked to several adverse outcomes the elderly population. Objective of study was investigate association mild (hemoglobin concentrations: 10.0–11.9/12.9 g/dL women/men) with all-cause mortality over 11–15 and effect change status on young-old (65–84 years) old-old (80+ years). Methods The Health Anemia Monzino 80-plus are two door-to-door, prospective population-based...
The unwillingness to share contacts is one of the least explored aspects COVID-19 pandemic. Here we report factors associated with resistance collaborate on contact tracing, based results a nation-wide survey conducted in Italy January-March 2021.The repeated cross-sectional on-line was among 7,513 respondents (mean age 45.7, 50.4% women) selected represent Italian adult population 18-70 years old. Two groups were defined direct question response expressing (1) or (2) willingness names...
Abstract Background Overt hyperthyroidism and hypothyroidism are regarded as possible causes of reversible dementia. Evidence on the risk dementia associated with subclinical thyroid dysfunctions is limited barely existent in very old, while findings conflicting. Objective: To cross‐sectionally longitudinally investigate association subclinical‐hyperthyroidism subclinical‐hypothyroidism a prospective population‐based study 80‐years or older residents Varese province, Italy (Monzino 80‐plus...