A5100678608- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Combustion and flame dynamics
- Advanced machining processes and optimization
- Cancer, Lipids, and Metabolism
- Lung Cancer Research Studies
- Cancer Immunotherapy and Biomarkers
- MicroRNA in disease regulation
- Lung Cancer Treatments and Mutations
- Circular RNAs in diseases
- Advanced Combustion Engine Technologies
- Advanced Surface Polishing Techniques
- Intraperitoneal and Appendiceal Malignancies
- Appendicitis Diagnosis and Management
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Hypoxia, and Metabolism
- Mycobacterium research and diagnosis
- T-cell and B-cell Immunology
- Glycosylation and Glycoproteins Research
- Bacteriophages and microbial interactions
- 3D Printing in Biomedical Research
- Nanoplatforms for cancer theranostics
- Bone Tissue Engineering Materials
- RNA Research and Splicing
- Inflammatory Biomarkers in Disease Prognosis
Chongqing Maternal and Child Health Hospital
2025
Beike Biotechnology (China)
2025
Beijing University of Chinese Medicine
2024
Affiliated Hospital of Hebei University
2016-2024
Zhongnan Hospital of Wuhan University
2018-2024
Wuhan University
2018-2024
China University of Mining and Technology
2023-2024
Capital Medical University
2012-2024
Harbin Engineering University
2017-2024
Zhengzhou University
2024
Rationale: Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies in world. Apart from traditional surgical resection, radiotherapy, and chemotherapy, more recent techniques such as nano-photothermal therapy biotherapy are gradually being adopted for treatment HCC. This project intends to combine advantages nanoscale drug delivery systems with targeting ability CAR-T cells. Method: Based on cell membrane-coated nanoparticles membrane-targeting modifications, a novel...
Propolis contains a variety of bioactive components and possesses many biological properties. This study was designed to evaluate potential effects Brazilian green propolis on glucose metabolism antioxidant function in patients with type 2 diabetes mellitus (T2DM). In the 18-week randomized controlled study, enrolled T2DM were randomly assigned group (900 mg/day) (n = 32) control 33). At end no significant difference found serum glucose, glycosylated hemoglobin, insulin, aldose reductase or...
Hepatocellular carcinoma is the fourth leading cause of cancer-related deaths globally.
Lung cancer (LC) is the second-highest incidence and first-highest mortality worldwide. Early screening precise treatment of LC have been research hotspots in this field. Artificial intelligence (AI) technology has advantages many aspects widely used such as early diagnosis, differential classification, prognosis prediction. This study aims to analyze visualize history, current status, hotspots, development trends artificial field lung using bibliometric methods, predict future directions...
Abstract Serum deprivation-response protein (SDPR), a phosphatidylserine-binding protein, which is known to have promising role in caveolar biogenesis and morphology. However, its function hepatocellular carcinoma (HCC) was still largely unknown. In this study, we discussed the characterization identification of SDPR, present it as novel apoptosis candidate incidence HCC. We identified 81 HCC cases with lower SDPR expression tumor tissues help qRT-PCR assay, potentially associated poor...
Taste preference drives food selection, acceptance, or rejection and influences nutritional status body mass index. Nevertheless, there are few reports concerning pregnant women. Mala flavor, characterized by its "numbing" "spicy" sensations, is a distinctive taste of Sichuan cuisine, created the combination Chinese prickly ash chili peppers. We conducted cohort study in Chongqing, China to analyze impact on excessive gestational weight gain (GWG). The included 495 women aged 20-45 years,...
Cognitive diagnosis can infer the students' mastery of specific knowledge concepts based on historical response logs. However, existing cognitive diagnostic models (CDMs) represent proficiency via a unidimensional perspective, which can't assess each concept comprehensively. Moreover, Q-matrix binarizes relationship between exercises and concepts, it latent concepts. Especially, when granularity attributes refines increasingly, becomes incomplete correspondingly sparse binary representation...
Homologous recombination deficiency (HRD) has emerged as a critical prognostic and predictive biomarker in oncology. However, current testing methods, especially those reliant on targeted panels, are plagued by inconsistent results from the same samples. This highlights urgent need for standardized benchmarks to evaluate HRD assay performance. In phases IIa IIb of Chinese Harmonization Project, we developed ten pairs well-characterized DNA reference materials derived lung, breast, melanoma...
Diabetic retinopathy (DR), a common complication of diabetes mellitus, is leading cause vision loss, yet its molecular mechanisms remain poorly understood. This review explores key genes implicated in DR—ubiquitin-like modifier activating enzyme 1 (UBA1), programmed cell death 11 (PDCD11), mitochondrial ribosomal protein S12 (MRPS12), S5 (MRPS5), RNA polymerase I subunit C (POLR1C), proto-oncogene tyrosine-protein kinase Src (SRC), glycogen synthase 3 beta (GSK3B), superoxide dismutase 2...
Purpose: Anti-programmed cell death receptor-1 (PD-1) antibodies have demonstrated antitumor activity in many cancer entities. Hepatic adverse events (AEs) are one of its major side effects, but the overall risks not been systematically evaluated. Thus, we conducted this meta-analysis to investigate incidence and risk developing hepatic AEs patients treated with PD-1 inhibitors. Methods: PubMed, Embase, oncology conference proceedings were searched for relevant studies. Eligible studies...
Abstract Our previous studies have indicated that long noncoding RNA (lncRNA) SPRY4 intronic transcript 1 (SPRY4‐IT1) was highly expressed in hepatocellular carcinoma (HCC). However, it still remained unclear how SPRY4‐IT1 worked tumorgenesis HCC. In this study, we tested the overexpression of HCC tissues and cells through a quantitative real‐time polymerase chain reaction. Statistical analyses showed upregulation had an association with tumor node metastasis stage, thrombin time, alkaline...
MicroRNA-205 (miR-205) was revealed as a novel diagnostic and prognostic biomarker for lung cancer, but the results in published papers were inconsistent. This meta-analysis aimed to investigate roles of miR-205 patients with cancer. Totally, 16 eligible articles included, among which 10 investigated value miR-205, 5 examined its values, 1 article studied both values. For meta-analysis, pooled sensitivity, specificity, positive likelihood ratio, negative odds overall area under curve cancer...